Clinical trials: Spinal Disorder
Spinal Tumor, Spinal Disorder
Duke Spine Outcome Study (DSOS)
The primary goal of this registry is to increase the knowledge about spine tumors and other spine disorders to guide appropriate management strategies for the future.
- Trial name
- DSOS (NCT04217525)
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Duke University
SCI - Spinal Cord Injury
Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular Health
The study is designed to investigate the effects of passive heat therapy on blood vessel health in 40 people (48 enrolled with attrition rate of 20%).
- Trial name
- IIS_SCIDoD (NCT07317843)
- Testing
- HEAT - Passive Heat Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Spinal Cord Injuries, Urinary Bladder, Neurogenic
Heart Rate Variability and Anxiety During Urinary Bladder Catheterization
This is a prospective, randomised study investigating the physical and psychological experience of intermittent catheterization in adult individuals following spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries, Urinary Bladder, Neurogenic, Anxiety State, Catheter Complications
- Trial name
- NCT05380661
- Testing
- Self-catheterization, Catheterization performed by urology nurse, participant blinded to time of procedure, Catheterization performed by urology nurse, participant aware of time of procedure
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Spinal Anesthesia, Anxiety
The Effect of Preoperative Anxiety Level on Vasovagal Events During Spinal Anesthesia and the Incidence of Vasovagal Events
To determine the anxiety levels of patients undergoing spinal anesthesia before surgery and to observe the effect of this anxiety level on vasovagal events that may be observed during spinal anesthesia.
- Trial name
- NCT07450014
- Where
- Turkey (Türkiye)
- Volunteers
- 1,500 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Spinal Pathologies, Pain
Patient Reported Outcome Measurements Registration in Spinal Pathologies and Neuromodulation
Longitudinal prospective observational data collection with questionnaires and categorical diagnostic and therapeutic registration and follow-up in spinal pathologies and neuromodulation
- Conditions
- Spinal Pathologies, Pain, Cervical Pain, Lumbar Pain Syndrome
- Trial name
- PROMSPINE (NCT07552519)
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- Jessa Hospital
Spinal Cord Injuries and Disorders
Mobile Manual Standing Wheelchair for SCI
People with spinal cord injuries (SCI) are particularly prone to complications from excessive sitting, because many are not able to stand without support.
- Trial name
- MMSW-SCI (NCT04668326)
- Testing
- Manual Standing Wheelchair, Mobile Manual Standing Wheelchair
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Static Spinal Disorder
Interest of Walking Sticks to Increase Walking Activity of People With Sagittal Imbalance of Spine
The purpose of this pilot study is to assess the impact of using walking sticks on walking perimeter in people with anterior spinal imbalance.
- Trial name
- WALKSPINE (NCT07127250)
- Testing
- Walking sticks
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Parkinson's Disease (PD), Gait Disorders
Effects of the Stimulation Site of tsMS With TMS on Functional Mobility in Individuals With Parkinson's Disease
This randomized clinical trial aims to compare the effects of two different trans-spinal magnetic stimulation (tsMS) application sites, cervical versus thoracic, when combined with repetitive transcranial magnetic stimulation…
- Conditions
- Parkinson's Disease (PD), Gait Disorders, Transcranial Magnetic Stimulation, Spinal Cord Stimulation
- Trial name
- NCT07488026
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cervical Trans-spinal Magnetic Stimulation, Thoracic Trans-spinal Magnetic Stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Spinal Cord Injuries, Respiration Disorders
Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury
Respiratory complications are among the leading causes of death in patients with chronic spinal cord injury (SCI). Our previous work showed that pulmonary function can be improved by using our original respiratory training…
- Trial name
- NCT06019949
- Testing
- Transcutaneous spinal cord stimulator, Respiratory Training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Spinal Cord Injuries, Gait Disorders, Neurologic
Safety and Feasibility of TWIICE Rise - Phase 2
The aim of this study is to assess the safety and the feasibility of two versions of TWIICE Rise for exoskeleton-assisted ambulation in patients with a spinal cord injury.
- Trial name
- NCT07461259
- Testing
- TWIICE Rise
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- TWIICE
Spinal Cord Injuries, Bowel Dysfunction
Noninvasive Spinal Cord Stimulation for Early SCI
The investigators are looking to determine the safety and efficacy of non-invasive transcutaneous spinal cord stimulation (TSCS) in promoting recovery of lower urinary tract (LUT), bowel, sexual, and cardiovascular function, as…
- Conditions
- Spinal Cord Injuries, Bowel Dysfunction, Sexual Dysfunction, Autonomic Dysfunction
- Trial name
- NCT06587841
- Testing
- Spinal COrd NEuromodulation™ (SCONE™) for transcutaneous spinal cord stimulation (TSCS)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
User of an Upper Limb Assistance Device, User Experience
Impact Study on Users of Upper Limb Assistive Devices
This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and…
- Conditions
- User of an Upper Limb Assistance Device, User Experience, Post-stroke, Spinal Cord Injury
- Trial name
- AMUSE (NCT07429188)
- Testing
- interviews and questionnaires
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Association APPROCHE
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Spinal Cord Injury/Disorder
Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators
The purpose of this study is to evaluate a new control (i.e., the vision-guided shared (VGS) control) for a wheelchair-mounted assistive robotic manipulator among powered wheelchair users.
- Trial name
- ARM Control (NCT04323449)
- Testing
- Compare two control methods for a wheelchair-mounted robotic manipulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Stroke, Visual Defects
Differentiation of Human Body Balance Disorders
Our research aims to analyze the possibilities of functional assessment of imbalances in the human body. Using the available, commonly known and used tests and devices for objective examination of static and dynamic body balance…
- Conditions
- Stroke, Visual Defects, Labyrinth Diseases, Cervical Spine Degenerative Disease
- Trial name
- NCT07395180
- Testing
- Patients after stroke, Patients with posterior columns of the spinal cord, Patients with labyrinth diseases
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Posttraumatic Stress Disorder, Spinal Cord Injuries
Outcomes After Spinal Cord Injury (OASIS)
The study evaluates the effectiveness of Prolonged Exposure Therapy on a population of individuals with spinal cord injuries. Participants will be randomly assigned to either a treatment as usual or Prolonged Exposure therapy…
- Trial name
- NCT03624218
- Testing
- Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor Research Institute
Spinal Cord Injuries, Depression
Dosing rTMS for Depression Post-SCI
Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population.
- Conditions
- Spinal Cord Injuries, Depression, Depressive Disorder, Major
- Trial name
- NCT05553353
- Testing
- repetitive transcranial magnetic stimulation--Active
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries, Gait Disorders, Neurologic
Effectiveness of a Powered Exoskeleton Combined With FES for Patients With Chronic SCI: a RCT
While there are a number of prospective studies evaluating powered exoskeletons in SCI patients, to date, not a single well-designed, randomized clinical trial has been published.
- Trial name
- Ekso-FES (NCT05187650)
- Testing
- Ekso (EksoNR, Ekso Bionics), FES (RehaMove2, Hasomed)
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- Mario Widmer