Clinical trials: Sperm
Inguinal Hernia
Isolation of the Spermatic Cord in Mesh Inguinal Hernia Repair
There are in excess of 1 million operations performed annually to repair inguinal hernias, mostly in the male population. Unfortunately, some patients continue to suffer both groin or testicular pain for varying lengths of time…
- Trial name
- NCT01391455
- Testing
- Isolation of the spermatic cord from mesh
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Chatham Kent Health Alliance
Sperm, Fertility
Ejaculation Frequency and Semen Parameters
The goal of this observational study is to determine whether the frequency of ejaculation in men had an effect on semen parameters..
- Trial name
- EFASP (NCT06172504)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- The First Hospital of Jilin University
Polycystic Ovarian Syndrome, Subfertility
Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)
Our study is observational, we are observing data from routine measurements during IVF/ICSI. Our study does not assess IVF/ICSI as an intervention, we are evaluating the role of FSI and preovulatory count which are calculated by…
- Conditions
- Polycystic Ovarian Syndrome, Subfertility, ICSI
- Trial name
- NCT02190006
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
HIV-1, Fertility
Intrauterine Insemination In HIV-Discordant Couples
This study aims to assess the feasibility of a novel standard of care technique for intrauterine insemination (IUI) in HIV-discordant couples in the United States.
- Conditions
- HIV-1, Fertility, Infertility
- Trial name
- ARTEMIS (NCT01173276)
- Testing
- Sperm Washing with Intrauterine Insemination (IUI)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Asthenozoospermia
Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers
Although several studies have considered the relationship between infertility and semen super oxide radical scavengers levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on superoxide…
- Trial name
- NCT02217189
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Babylon University
Male Infertility, Heart Valve Disease
Warfarin Effects on Male Fertility After Cardiac Surgery
Young male patients undergoing cardiac surgery may require oral anticoagulation with warfarin either lifelong, such as after mechanical valve replacement, or for a limited postoperative period, for example following valve repair…
- Trial name
- NCT07330869
- Testing
- Semen analysis, sperm DNA fragmentation and hormonal evaluation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Città di Lecce Hospital, GVM Care & Research
Azoospermia, Nonobstructive
TESE and Non Obstructive Azoospermia
Azoospermia is complete absence of sperm in the ejaculate. It accounts for 10-15% of male infertility cases. It is classified as obstructive and non-obstructive azoospermia (NOA). NOA constitutes 60% of all cases of azoospermia.
- Trial name
- NCT03146260
- Testing
- Conventional TESE, Microdissection TESE
- Volunteers
- 148 people
- Sponsor
- Assiut University
Fertility Disorders
Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI
Intrauterine Granulocyte colony stimulating factor (GCSF) was compared with intrauterine Human Chorionic Gonadotropin (HCG) in increasing clinical pregnancy rate as a primary outcome and ultrasound imaging of gestational sac as a…
- Trial name
- NCT04606082
- Testing
- Granulocyte Colony Stimulated Factor, Human Chorionic Gonadotropins
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Fertility, In Vitro Fertilization
A Study Comparing a Shorter Exposure of Oocyte to Spermatozoa Versus a Standard Incubation on the Live Birth Rate of In-vitro Fertilization Treatment
In vitro fertilization (IVF) treatment is now commonly used to treat infertile couples. During IVF treatment, oocytes and sperm are routinely incubated overnight and this may lead to suboptimal culture conditions because of…
- Trial name
- NCT02534857
- Testing
- a shorter exposure of oocyte to spermatozoa
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Fertility, SPERM
Male Fertility and Sperm Cryopreservation
PURPOSE: Primary objective: To assess the feasibility and outcomes of male fertility preservation by sperm freezing prior to starting treatment requiring alkylating agents and/or total body irradiation.
- Conditions
- Fertility, SPERM, Cancer
- Trial name
- NCT02431000
- Testing
- Sperm and blood collected for analysis
- Where
- United States
- Sponsor
- University of Tennessee
Abnormal Spermatogenesis, Azoospermia
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility
The aim of this study was to assess meiotic recombination in primary spermatocytes, synaptonemal complex length and the correlation with chromosomal abnormalities in testicular spermatozoa from infertile men with idiopathic…
- Trial name
- NCT02339272
- Testing
- non interventional
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Igenomix
Male Infertility
Effect of Sorting of Apoptotic Spermatozoa on the Outcome of Assisted Reproduction
In assisted reproductive technology (ART) semen needs to be processed. Commonly used methods rely on physical properties of the spermatozoa, such as the swim-up methods and density gradient centrifugation.
- Trial name
- Spermsorting (NCT02166567)
- Testing
- Staining of spermatozoa with the YoPro dye and sorting of the stained spermatozoa with FACS, Swim-up
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Endometrioma
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients
Investigators compare ICSI results for endometrioma patients with or without cyst aspiration if more than 5cm \&with or without GnRh agonists for all endometrioma patients
- Trial name
- GnRh (NCT02737800)
- Testing
- endometrioma aspiration, GnRh agonist ( Decapeptyl ), standard long stimulation protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kasr El Aini Hospital
Infertility
Reduction of Sperm DNA Fragmentation by Oral Ginger
This study is a randomized, double blind, controlled clinical trials assess the efficacy of the ginger oral treatment on sperm DNA fragmentation, sperm parameters and male hormones.
- Trial name
- NCT02032251
- Testing
- oral administration of ginger
- Where
- Iran
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertile Patients
the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval.
- Trial name
- NCT06937645
- Testing
- Hyaluronic Acid (HA), platlet rich plasma (PRP)
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Nahrain University
Covid19, Infertility, Male
Impact of the Coronavirus Disease 2019 (COVID-19) on Sperm Parameters
This study aims to better understand the effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, virus that causes the coronavirus disease 2019 (COVID-19), on male fertility.
- Trial name
- NCT04937608
- Testing
- Sperm analysis
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Fertilys
Male Infertility
Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy
In the current study, the adult infertile patients with clinical varicoceles will be included. the patients will undergo subinguinal varicocelectomy.
- Trial name
- NCT06257459
- Testing
- subinguinal varicocelectomy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Fertility, Male Fertility
Sperm, Exposure and Endocrine Disruptors
The proposed research aims to 1) measure male participants' urinary levels of EDCs and sperm quality before and after report-back and EDC reduction intervention and assess changes, 2) assess the extent to which MM's program…
- Conditions
- Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
- Trial name
- SEED (NCT07703046)
- Testing
- EDC Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Million Marker Wellness, Inc.
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co
Intracytoplasmic Sperm Injection, Sperm
Sperm Selection by Rheotaxis and Thermotaxis in In-Situ Handmade Microfluidics of Fluidic Walls in the Same ICSI Plate
Microfluidics technologies are proving their capability to select suitable sperm for ICSI, especially those that take advantage of the rheotaxic properties of sperm migration.
- Conditions
- Intracytoplasmic Sperm Injection, Sperm, Microfluidics
- Trial name
- IS-MFluidics (NCT06243926)
- Testing
- Sperm selection for ICSI
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CREA Medicina de la Reproducción SL