Clinical trials: Speech Disorders in Children
Cognition Disorder
Cognitive and Speech Disorders in Children With Congenital Heart Defects
The study is aimed to found out expressive speech disorders as a sign of neurocognitive development delay in children with congenital heart defects before and after surgery
- Trial name
- NCT06565299
- Testing
- Cardiovascular surgery with cardiopulmonary bypass
- Where
- Russia
- Volunteers
- 217 people
- Sponsor
- Kemerovo State Medical University
Autism, Communication Disorders
iPad Application to Treat Prosodic Deficits in Students With Communication Disorders
The purpose of this study is to evaluate the utility of a specialized iPad application designed to treat difficulties with intonation (e.g., melody in voice) in children with autism spectrum disorders (ASD) and other…
- Trial name
- NCT01917864
- Testing
- iPad Application
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Autism, Autism Spectrum Disorder
Word Learning From Parentese in Autistic Children
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are…
- Conditions
- Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT06649916
- Testing
- Parentese Speech, Adult Registered Speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Teletherapy in Children Who Are Deaf and Hard of Hearing
This study seeks to determine the effectiveness of speech/language teletherapy to address disparities in speech and language outcomes in children who are deaf or hard-of-hearing (D/HH).
- Trial name
- NCT04928209
- Testing
- Speech-Language Teletherapy
- Where
- 5 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of California, San Francisco
Stuttering, Childhood
Correlation of Family History, Age at Onset & Severity of Stuttering
The aim of this study is to Detect the influence of the family history of stuttering (distance of relative) on the onset and severity of stuttering in children in these families.
- Trial name
- NCT04412213
- Testing
- Stuttering severity instrument for school-age children (SSI-3 Arabic version)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Developmental Language Disorder
Training Inner Speech in Children With Developmental Language Disorder
The complex and unclear relationship between language and executive function (EF) creates barriers to developing effective interventions for children with developmental language disorder (DLD) whose language difficulties often…
- Trial name
- NCT06880731
- Testing
- Modeling with Verbal Mediation, Modeling Only
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Speech Sound Disorder
Treatment for /s/ Production Errors in Children With Speech Sound Errors
We want to learn about a new way to help people make the /s/ sound, like in the word "snake." We will be studying a way to teach the /s/ sound that uses very short speech sessions.
- Trial name
- SPLITS-S (NCT07214480)
- Testing
- Motor-based speech treatment
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Syracuse University
Hearing Disorders in Children, Hearing Loss
Automated Measures of Speech Intelligibility Using Brain Wave Recordings
Hearing loss is one of the most prevalent impairments in the world. The World Health Organization estimates that as of 2020, around 466 million people worldwide are affected by disabling hearing loss, of which 34 million are…
- Trial name
- CORGEE (NCT06402994)
- Testing
- Electrophysiological experiment, Speech audiometry
- Where
- 4 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hearing Loss, Sensorineural
Paraverbal Components of Language and Cochlear Implant
The investigators evaluated patients older than 6 years old, with severe hearing loss, cochlear implant wearers, able to perform a series of tests (TUISE, the pitch discrimination test, the melody discrimination test, VAS) to…
- Trial name
- NCT05950412
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Speech Perception
Improving Perception of Speech in Noise in Children With Communication Disorders
Smarty Ears has developed a prototype of an innovative therapeutic training system to improve speech perception in noise by training children on interrupted noise (which has silent intervals that allow for fragments of the target…
- Trial name
- L2F (NCT04473729)
- Testing
- Audiovisual speech training in noise for children
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Smarty Ears
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Language Delay, Language; Developmental Disorder, Expressive
Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders
The investigators have designed an innovative proof-of-concept trial designed to provide data as to whether the speech difficulties in children with developmental dysphasia (DD) are improved with intranasal inhalations of…
- Conditions
- Language Delay, Language; Developmental Disorder, Expressive, Language; Developmental Disorder, Receptive, Autism Spectrum Disorder
- Trial name
- NCT04689282
- Testing
- Bioactive Factors, Produced by M2 Type Macrophages (M2-BFs).
- Where
- Russia
- Volunteers
- 14 people
- Sponsor
- Russian Academy of Medical Sciences
Cerebral Palsy Children, Children With Traumatic Brain Injury
Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor handicap among children. The economic burden of CP in USA includes $1.18 billion in direct medical costs, $1.05 billion in direct non-medical costs, and an additional $9.24…
- Conditions
- Cerebral Palsy Children, Children With Traumatic Brain Injury, Mental Handicap, Delayed Speech Development
- Trial name
- NCT02116348
- Testing
- Cerebrolysin (Nerve growth factor)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Language Development Disorders
Virtual Reality-supported Language Intervention for Preschool Children With DLD
This study aims to test the effectiveness of virtual reality-supported speech therapy in improving basic language skills in children aged 3 to 6 years diagnosed with Developmental Language Disorder (DLD).
- Trial name
- NCT07438639
- Testing
- Virtual Reality Rehabilitation System (VRRS), Taditional Speech Therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cleft Palate Children, Speech Disorders in Children
Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate
Speech therapy in children with a palate deals with two scientific challenges that will be addressed in this project. The first challenge is selecting the best speech approach for a child with a specific cleft speech…
- Conditions
- Cleft Palate Children, Speech Disorders in Children, Cleft Lip and Palate, Speech Therapy
- Trial name
- NCT06105099
- Testing
- Motor-phonetic intervention, Phonological intervention, Combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 135 people
- Sponsor
- University Ghent
Autism Spectrum Disorder, Autism
Parent-implemented Social Communication Treatment in Preschool Children With Autism Spectrum Disorder
An accumulation of research evidence has pointed to parent-implemented communication treatment as effective in reducing the severity of social communication deficits in preschool children with ASD.
- Conditions
- Autism Spectrum Disorder, Autism, Social Communication, Speech Therapy
- Trial name
- NCT05455411
- Testing
- Group-based Parent-implemented Training, Individual-based Parent-implemented Training
- Where
- 2 sites in Hong Kong
- Volunteers
- 112 people
- Sponsor
- Chinese University of Hong Kong
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate
Expiratory Muscle Strength Training for Hypernasal Speech in Children
When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency.
- Conditions
- Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence
- Trial name
- NCT05492266
- Testing
- Expiratory Muscle Strength Training, Maintenance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Noel Jabbour
Childhood Apraxia of Speech
Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children
This study will investigate the feasibility of applying the Rapid Syllable Transition Treatment (ReST) protocol in children with Childhood Apraxia of Speech, considering the scarcity of evidence in the context of Brazilian…
- Trial name
- ReST-SSD (NCT07636031)
- Testing
- Rapid Syllable Transition Treatment (ReST)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira