Clinical trials: Spatial Navigation
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments Study 2
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- HEAR3D_CE2 (NCT03774030)
- Testing
- several virtual 3-D complex audio environments
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Spatial Learning
The Impact of Physical Exercise on Navigation Performance in Soldier
20 healthy man, 10 in trial group and 10 in control group (randomly divided) will participate in the experiment on order to evaluate if improvement in physical fitness influences spatial learning in humans.
- Trial name
- NCT02831036
- Testing
- training program, VO2max test, spatial orientation test
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Low Vision, Orientation
SmartHMD for Improved Mobility
The National Eye Institute estimated about 3 million people over age 40 in the US had low vision in 2010 and projects an increase to nearly 5 million in 2030 and 9 million in 2050.
- Conditions
- Low Vision, Orientation, Mobility Limitation, Navigation, Spatial
- Trial name
- NCT03781583
- Testing
- SmartHMD version 1, SmartHMD version 2, SmartHMD version 3
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- James Weiland
Isolation, Social, Virtual Reality
Brain Changes in Response to Long-Duration Isolation and Confinement
This study investigates the time course and magnitude of eight months of isolation and confinement in a spaceflight analog facility on brain changes and cognitive performance.
- Conditions
- Isolation, Social, Virtual Reality, Spatial Navigation
- Trial name
- BRAIVE (NCT04532866)
- Testing
- Isolation and Confinement
- Where
- Russia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments Study 3 (HEAR3D_CE3)
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- NCT04180254
- Testing
- Effect of several processing on the auditory distance perception
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- NCT03514758
- Testing
- several virtual 3-D complex audio environments
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Alzheimer Disease, Aging
Spatial and Ocular Trajectories for the Early Diagnosis of Alzheimer's Disease.
Spatial navigation is a high-level cognitive function that enables humans to orientate themselves and move around in space by constructing a mental representation of the environment.
- Trial name
- ACTSOMA (NCT06213766)
- Testing
- Cognitive assessment, Questionnaires, Spatial navigation task with eye-tracking.
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mild Cognitive Impairment, Alzheimer's Disease
Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation
Remembering how to travel from one location to another is critical in everyday life, yet this vital ability declines with normal aging and can be further affected by conditions that disproportionately affect the elderly, such as…
- Trial name
- NCT01958437
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Epilepsy Lobe Temporal, Healthy
Spatial Memory and Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE) can cause memory disorders, including long-term forgetfulness due to a failure to consolidate verbal but also spatial information.
- Conditions
- Epilepsy Lobe Temporal, Healthy, Epilepsy
- Trial name
- EPINAVIG (NCT06847152)
- Testing
- spatial memory test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Liver Cancer, Surgery
Navigated Laparoscopic Microwave Ablation of Tumor Mimics in Pig Liver - an Ex-vivo Trial
In primary and secondary liver tumors microwave ablation could be an alternative to surgical resection.It could be performed laparoscopically.
- Conditions
- Liver Cancer, Surgery, Navigation, Spatial
- Trial name
- NCT04106453
- Testing
- navigated microwave ablation, ultrasound guided navigation
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- Universitätsklinikum Köln
Inner Ear Disease, Equilibrium; Disorder, Labyrinth
Unilateral Peripheral Vestibular Dysfunction: Reeducation and Spatial Orientation.
Motor control includes postural control and voluntary movement. For an optimal motor control it is necessary that brain integrates vestibular, visual and somatosensorial inputs properly, in a nonlinear way.
- Conditions
- Inner Ear Disease, Equilibrium; Disorder, Labyrinth, Spatial Navigation
- Trial name
- NCT03171181
- Testing
- Vestibular reeducation
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Aging, Anxiety
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress…
- Conditions
- Aging, Anxiety, Memory Impairment
- Trial name
- NCT03896529
- Testing
- Anticipatory psychological stress
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Spine Fusion, Spine Injury
Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
The primary study objective is to build a video dataset, consisting of both colour and depth information, of spine surgery that includes both 'open' and 'minimally invasive' (MIS) surgeries.
- Conditions
- Spine Fusion, Spine Injury, Spine Degeneration, Navigation, Spatial
- Trial name
- SPIVOS (NCT06580379)
- Testing
- Spine surgery
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Traumatic Brain Injury
Combinated Cues and Virtual Spatial Navigation
Many patients suffer from a topographical disorientation after a traumatic brain injury. Virtual Reality settings allow us to develop navigational cues, in order to rehabilitate patients or to help them in daily life.
- Trial name
- CombiVirtual (NCT03534128)
- Testing
- Evaluation of the effect of cues on virtual spatial navigation using a virtual district
- Where
- 4 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Ressources Francilien du Traumatisme Crânien
Brain Injuries, Traumatic, Brain Injury Traumatic Severe
Online Memory Intervention for Individuals with Traumatic Brain Injury
This study will examine the behavioural and neurophysiological efficacy and feasibility of an online spatial navigation intervention for improving memory and brain health in individuals who have sustained moderate-severe…
- Conditions
- Brain Injuries, Traumatic, Brain Injury Traumatic Severe, Brain Injury Traumatic Moderate, Brain Injury, Chronic
- Trial name
- NCT04331392
- Testing
- Spatial Navigation Intervention, Educational Videos
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Toronto Rehabilitation Institute
Brain Neoplasms, Cerebral Aneurysm
Clinical Trial for the Validation of AR Based Neuronavigation System
The goal of this clinical trial is to test augmented reality (AR) based neuronavigation system in surgeries for patients of brain neoplasm or cerebral vascular disease.
- Conditions
- Brain Neoplasms, Cerebral Aneurysm, Cerebral Arteriovenous Malformation, Navigation, Spatial
- Trial name
- NCT05776706
- Testing
- AR-based navigation
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Visual Impairment
Digital Twin Smart Educational Platform for Visually Impaired Navigation Training
This study evaluates a novel digital twin smart educational platform designed to train visually impaired individuals on safe navigation in Saudi urban environments.
- Trial name
- NCT07641127
- Testing
- Adaptive Multi-modal Digital Twin Navigation Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- King Salman Center for Disability Research
Cerebral Palsy (CP)
Cortical Correlates of Spatial Navigation Skills in an Immersive Virtual Reality Environment
The goal of this study is to investigate the neural mechanisms that undergoes spatial navigation skills in children/adolescents aged between 8 and 17 years.
- Trial name
- NCT06710301
- Testing
- Preliminary assessment, Navigation task with EEG recording
- Where
- 2 sites in Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Traumatic Brain Injury
Non-invasive Deep Brain Stimulation to Improve Spatial Navigation Abilities in Individuals Following Traumatic Brain Injury
Impairments in spatial memory and spatial navigation are commonly reported amongst patients presenting post-traumatic brain injury (TBI).
- Trial name
- NCT07271524
- Testing
- Transcranial electric stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 25 people
- Sponsor
- Friedhelm Hummel
Mild Cognitive Impairment, Spatial Navigation
Active Navigation Training
Pilot testing and development of an immersive virtual reality system for spatial navigation training in mild cognitive impairment syndrome.
- Trial name
- ANTaging (NCT05768620)
- Testing
- CAVE, TAU
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Auxologico Italiano