Clinical trials: Spatial Learning
Amblyopia
Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia
The research deals with amblyopia or lazy eye, a condition that affects about 3% of the population, and results in a variety of visual deficits.
- Trial name
- NCT03109314
- Testing
- Donepezil, Single-letter training, Uncrowd training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dennis Levi
Schizophrenia
A Study to Evaluate the Effects of Once Daily Doses of AQW051 on Cognition, in Stable Schizophrenia Patients
This is a study in chronic stable Schizophrenia with the purpose to answer the question of whether agonism of the nicotinic alpha7 receptor is capable of enhancing cognition in a well defined chronic stable patient population…
- Trial name
- NCT01730768
- Testing
- AQW051
- Where
- 13 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novartis Pharmaceuticals
Hearing Loss, Health Literacy
Mechanisms of Health Literacy and Information Accessibility in the Deaf
The purpose of this proposal is to examine the attitudes, knowledge, and skills related to health information that influence health literacy among Deaf individuals.The study team will also examine frequently overlooked potential…
- Trial name
- HIL (NCT03093779)
- Testing
- Health Information Assessment
- Where
- 3 sites in United States
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Amblyopia
An Active Approach to Treat Amblyopia: Video Game Play
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast.
- Trial name
- NCT01223716
- Testing
- Perceptual learning, Video Game, Crossover (Occlusion therapy + Video Game)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Glioma
Spatial and Temporal Characterization of Gliomas Using Radiomic Analysis
Glioma are type of primary brain tumors arising within the substance of brain. Different type of gliomas are seen which are classified depending upon pathological examination and advanced molecular techniques, which help to…
- Trial name
- GLIO-RAD (NCT06036381)
- Testing
- Radiomic analysis of imaging - MRI, PET, CT
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Tata Memorial Centre
Virtual Reality and Medical Education
Testing Efficacy of VR in Medical Education
Recent emergence and commercialization of immersive virtual reality (VR) shows great promise in its application to medical education.
- Trial name
- NCT04480489
- Testing
- VR, Traditional
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Visual Learning, Healthy Volunteers
Generalization and Specificity of Visual Learning During Sleep
A growing body of evidence suggests that sleep facilitates and is beneficial to perceptual learning. However, the underlying mechanism of this facilitatory action is largely unknown.
- Trial name
- Visuallearning (NCT07015840)
- Testing
- Visual perceptual learning
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Brown University
Hearing Loss, Tinnitus
Hearing Impairment, Cognitive Therapy and Coping
A randomized controlled study with hearing impaired workers, who have voluntarily signed up for an 8 session cognitive therapy (CBT) course The CBT intervention will be compared to a waiting list control group.
- Conditions
- Hearing Loss, Tinnitus, Stress, Psychological, Mental Fatigue
- Trial name
- NCT01206829
- Testing
- 8-session CBTcourse, 8 session cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Alzheimer Disease, Aging
Spatial and Ocular Trajectories for the Early Diagnosis of Alzheimer's Disease.
Spatial navigation is a high-level cognitive function that enables humans to orientate themselves and move around in space by constructing a mental representation of the environment.
- Trial name
- ACTSOMA (NCT06213766)
- Testing
- Cognitive assessment, Questionnaires, Spatial navigation task with eye-tracking.
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Sleep
Memory Consolidation in Pharmacologically Enhanced Naps
This study will examine whether various drugs affecting sleep cycles can improve different kinds of memory.
- Trial name
- NCT00777829
- Testing
- zolpidem
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders
Moving Yourself in Space and Time: MYSTIC
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare…
- Conditions
- Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders, Older Adults (60 - 85 Years Old)
- Trial name
- MYSTIC (NCT07697664)
- Testing
- Complex Rhythmic Movement Sequences (CRMS) Sessions
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Emory University
Stress, Learning, Spatial
Influence of Stress on Encoding and Prediction
The purpose of this study is to investigate the neural mechanisms by which acute stress influences statistical learning and episodic encoding.
- Trial name
- NCT05920161
- Testing
- Socially Evaluated Cold Pressor Test, Control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Psychotic Disorders
Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone
To assess the effect of risperidone 2 mg daily (QD) on the differential sensitivity of 2 spatial working memory tests (the GMLT and MDR) in non-agitated, drug-naive patients suffering from first-episode…
- Trial name
- NCT00174200
- Testing
- Risperidone 2 mg
- Where
- 3 sites in Canada, Russia
- Volunteers
- 20 people
- Sponsor
- Pfizer
Visual Impairment
Digital Twin Smart Educational Platform for Visually Impaired Navigation Training
This study evaluates a novel digital twin smart educational platform designed to train visually impaired individuals on safe navigation in Saudi urban environments.
- Trial name
- NCT07641127
- Testing
- Adaptive Multi-modal Digital Twin Navigation Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- King Salman Center for Disability Research
Healthy
Explore the Nature Factors Relevant to Learning-Pioneering Natural Factors That Influences Science Learning II
Genetic research has provided the most exciting breakthroughs in neuroscience and cognitive science. Partially genetically determined cognitive impairments have been described in people with COMT, 5HT6, BDNF (Swillen et al.…
- Trial name
- NCT00713570
- Where
- Taiwan
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy Older Adults
Modulation of Visual-Spatial Learning in Healthy Older Adults by tDCS
The aim of this study is to investigate whether a combination of intensive training of visual-spatial abilities (LOCATO task) with anodal transcranial direct current stimulation (tDCS) leads to an improvement of learning and…
- Trial name
- NCT02110056
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Healthy Young Adults
Modulation of Visual-Spatial Learning in Healthy Young Adults by tDCS
The aim of this study is to investigate whether a combination of intensive training of visual-spatial abilities (LOCATO task) with anodal transcranial direct current stimulation (tDCS) leads to an improvement of learning and…
- Trial name
- NCT02110407
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Anxiety Disorders
Spatial Context and Fear Learning
Background: Fear is a normal response to a threat. Learning fear can be helpful sometimes. For people with anxiety disorders, fear can be long-lasting and too intense.
- Trial name
- NCT02423044
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)