Clinical trials: Sore Throat
Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute
Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections
The goal of this clinical trial is to learn if trimethoprim-sulfamethoxazole (TMP-SMX) works to treat invasive infections due to methicillin-resistant Staphylococcus aureus (MRSA) in children.
- Conditions
- Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute, Septic Arthritis, Orbital Cellulitis
- Trial name
- NCT06982105
- Testing
- Trimethoprim Sulfamethoxazole
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Postoperative Sore Throat
Effect of Saline Lubrication on Post-intubation Complications
The purpose of this study is to evaluate the influence of none-lubricated dry tube on the incidence of Postoperative Sore Throat (POST) after general anesthesia with endotracheal intubation.
- Trial name
- Lubrication (NCT02492646)
- Testing
- Saline group, Dry group
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Laryngeal Injury, Hoarseness
Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
The goal of this randomized clinical trial is to compare two different orotracheal tubes in patients which require orotracheal intubation for general anesthesia.
- Conditions
- Laryngeal Injury, Hoarseness, Cough, Sore-throat
- Trial name
- Triglotix® (NCT06108271)
- Testing
- Triglotix®, Conventional endotracheal tube
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Tonsillitis
Celecoxib as a Post-tonsillectomy Pain Medication
The hypothesis is that celecoxib effectively reduces pain after a tonsillectomy and reduces post-operative narcotic use. To test this hypothesis, the study is placebo controlled (sugar pill).
- Trial name
- NCT00583453
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Iowa
Tonsillitis
Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children
The primary objective of this study is to demonstrate the non-inferiority, at the assessment visit (V3 (D10/D14)), in terms of bacteriological efficacy of pristinamycin (PRI) administered for 4 days versus amoxicillin (AMX)…
- Trial name
- PRI-angine (NCT00393744)
- Testing
- pristinamycin, amoxicillin
- Where
- France
- Volunteers
- 395 people
- Sponsor
- Sanofi
General Anesthesia
A Comparison of LMA-Supreme and I-gel for the Incidence of Postoperative Sore Throat
The purpose of this study is to investigate and compare the incidence of the postoperative sore throat between LMA supreme and I-gel.
- Trial name
- NCT02745964
- Testing
- LMA supreme, I-gel
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Yonsei University
Sore Throat
Dexmedetpmidine Versus Ketamine for Postoperative Sore Throat in Sinus Surgery
The aim of this randomized clinical trial is to evaluate the impact of dexmedetomidine versus ketamine soaked pharyngeal packing on postoperative sore throat in functional endoscopic sinus surgery (FESS).
- Trial name
- NCT04955158
- Testing
- Dexmedetomidine, Ketamine, saline 0.9%
- Where
- Egypt
- Volunteers
- 143 people
- Sponsor
- Assiut University
Throat Pain After EUS Insertion
A Comparison of Endoscopic Ultrasound Insertion Methods
Endoscopic ultrasonography (EUS) is an essential technique required in diagnosis of pancreatobiliary diseases. In previous studies, 6% of patients who undergone EUS had significant throat pain.
- Trial name
- NCT02924948
- Testing
- Balloon inflation
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Tonsillitis
Detection of Group A Streptococcus (GAS) in Oral Cavity
The investigators intend to screen children who are suspected of having GAS tonsillitis. From each child we will take a throat culture and saliva sample to screen for molecular evidence of GAS.
- Trial name
- NCT02972437
- Testing
- sample taking
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Postoperative Sore Throat, Cough, Hoarseness
Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy
Postoperative sore throat is the most common complication following general anesthsia with endotracheal intubation with incidence ranging from 21 to 65% Although usually self-limiting, it significantly affects patient's comfort…
- Trial name
- NCT07760272
- Testing
- Dexamethasone (0.1 mg/kg), Normal Saline (0.9% NaCl)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Gum Chewing, Sore Throat
Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation
This study aims to evaluate the effect preoperative chewing gums for 2 or 4 minutes on postoperative sore throat after general anesthesia using an endotracheal tube.
- Conditions
- Gum Chewing, Sore Throat, Endotracheal Intubation, Randomized Controlled Trial
- Trial name
- NCT05069844
- Testing
- Gum chewing for 2 minutes, Gum chewing for 4 minutes
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ahmed Salah Ahmed Abd Elgalil
Tonsillitis
Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy
Tonsillectomies are among the most common surgical procedures performed in pediatric populations, with more than 14,000 procedures performed annually in Ontario, with more than 80% being performed to treat sleep-disordered…
- Trial name
- NCT07176533
- Testing
- Suprazygomatic maxillary nerve block (SZMN) with bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obstructive Sleep Apnea, Tonsillitis
Pediatric Pain Optimization After Tonsillectomy
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.
- Conditions
- Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
- Trial name
- NCT05244226
- Testing
- Fentanyl/Hydromorphone, Methadone
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Thyroidectomy, Sore Throat
Effects of Flurbiprofen Spray and Ice Cream for Pain and Voice Outcomes After Thyroidectomy
Researchers will compare oral flurbiprofen (%0.25) spray and ice cream to a placebo (a look-alike substance that contains no drug) to see if oral flurbiprofen (%0.25) spray and ice cream works to effect post-thyroidectomy throat…
- Conditions
- Thyroidectomy, Sore Throat, Voice Quality
- Trial name
- NCT07531147
- Testing
- Flurbiprofen, Food Effect cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Katip Celebi University
Sore Throat, Post-Operative Sore Throat
Zinc Lozenges and Their Effect on Postoperative Sore Throat Syndrome
The objective of this study is to assess the effect of preoperative administration of oral zinc lozenges on the incidence of postoperative sore throat syndrome.
- Trial name
- NCT02405832
- Testing
- Zinc
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Vermont
Group A Streptococcal (GAS) Pharyngitis
Short Versus Standard Amoxicillin for Pediatric Strep Throat
The purpose of this study is to compare 5-day vs 10-day amoxicillin for strep throat in children.
- Trial name
- NCT07845812
- Testing
- 5 day short course antibiotic treatment, 10 day standard of care antibiotic treatment
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tonsillopharyngitis, Rhinopharyngitis
Trial To Assess Efficacy and Safety of PediaFlu® in Children With Acute Tonsillopharyngitis / Rhinopharyngitis
Sore throat or acute tonsillopharyngitis, often referred to as angina catarrhalis in Central and Eastern Europe, affects mainly children, adolescents and young adults and represents one of the most common reasons to consult a…
- Trial name
- NCT04899401
- Testing
- Standard of care + PediaFlù®, Standard of care
- Where
- 3 sites in Romania
- Volunteers
- 130 people
- Sponsor
- Pediatrica S.r.l
Pharyngitis Bacterial
A Multi-Site Clinical Evaluation of the ARIES Group A Strep Assay in Symptomatic Patients
A multi-center evaluation to assess the diagnostic sensitivity and specificity of the ARIES Group A Strep Assay will be established through a method comparison using prospectively collected, de-identified, clinical samples…
- Trial name
- NCT03037957
- Testing
- ARIES Group A Strep Assay
- Where
- 5 sites in United States
- Volunteers
- 704 people
- Sponsor
- Luminex Corporation
Acute Pharyngitis, Viral Sore Throat
Evaluation of Treatments for Sore Throat Associated With Acute Pharyngitis and/or Viral Tonsillitis
The objective of this study is to conduct post-marketing clinical follow-up of four products: HMG, PHN, PHR, and TUR. This follow-up will consist of collecting clinical data in real-life conditions to confirm the tolerance…
- Trial name
- PharyTol (NCT07569939)
- Testing
- HMG, PHN, PHR
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Clermont-Ferrand