Clinical trials: Sore Throat
Sore Throat
Efficacy and Safety of the Lysobact Complete Spray®, Tantum Verde® and Pharyngal® Oromucosal Spray in the Treatment of Acute Sore Throat
The primary objective of this multicenter, single-blind, randomized, placebo-controlled, prospective, comparative study with parallel design and 4-arms is to evaluate superiority of Lysobact Complete Spray® against placebo and…
- Trial name
- NCT03282045
- Testing
- Lysobact Complete Sprey, Tantum Verde® Spray, Pharyngal® Oromucosal Spray
- Where
- Bosnia and Herzegovina
- Volunteers
- 346 people
- Sponsor
- Bosnalijek D.D
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Streptococcal Pharyngitis, Group A Streptococcal Infection
A Multicenter Evaluation of SalivIQ™ Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute Pharyngitis
The goal of this observational study is to learn how well the SalivIQ™ Strep A test detects Group A Streptococcus, the bacteria that cause strep throat.
- Trial name
- NCT07891728
- Testing
- qPCR
- Where
- 3 sites in United States
- Volunteers
- 668 people
- Sponsor
- SalivIQ Diagnostics, Inc.
Group A Streptococcus: B Hemolytic Pharyngitis
Detection of GABHS in Throat Gargle
The objective of this study is to investigate the use of patient throat gargle as an alternative to throat swabbing for the diagnosis of pharyngitis caused by Group A β-Hemolytic Streptococcus (GABHS) infection, also known as…
- Trial name
- NCT03231098
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Gargle Tech
Pharyngitis
Evaluate the Time of Pain Relief of Fast Acting Aspirin Versus Acetaminophen in Subjects Diagnosed With Sore Throat Pain
This study is to evaluate the onset of relief provided by a single, oral dose of fast release aspirin 1000 mg compared to acetaminophen 1000 mg and placebo in subjects with sore throat pain.
- Trial name
- Tarot (NCT01453400)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Bayer
Pharyngitis, Pain
Ambroxol Spray Sore Throat Study
The development of a new Ambroxol spray formulation for the treatment of sore throat pain associated with acute pharyngitis requires an initial phase II study to be conducted in order to select the most appropriate dose for pain…
- Trial name
- NCT01361802
- Testing
- Ambroxol Spray
- Where
- 15 sites in South Africa
- Volunteers
- 494 people
- Sponsor
- Boehringer Ingelheim
Pain, Inflammation
Efficacy of Tinoridine in Treating Pain and Inflammation in Adults
The purpose of this study is to confirm the efficacy of tinoridine hydrochloride (HCL), three times daily (TID), in the treatment of pain and inflammation in patients with acute tonsillitis and/or acute pharyngitis of…
- Trial name
- NCT01224756
- Testing
- Tinoridine HCl
- Where
- 4 sites in Indonesia
- Volunteers
- 342 people
- Sponsor
- Takeda
Recurrent Upper-Respiratory Tract Infections
CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study
The purpose of this study is to assess the efficacy and safety of J022X ST for prevention of Recurrent Upper-Respiratory Tract Infections (RURTI) compared to placebo in children of younger age who develop infectious diseases more…
- Trial name
- NCT01948856
- Testing
- J022X ST
- Where
- 24 sites in Italy, Lithuania and 3 more
- Volunteers
- 1,003 people
- Sponsor
- Pierre Fabre Medicament
Pharyngitis, Infective
Validation of the GenePOC Strep A, C/G Assay for Detecting Group A, C and G β-hemolytic Streptococcus From Throat Swabs.
The primary purpose of this clinical investigation is to establish the performance of the GenePOC Strep A, C/G assay on the revogene.
- Trial name
- NCT03422341
- Testing
- Comparison between GenePOC CR and Reference Method
- Where
- 8 sites in United States, Canada
- Volunteers
- 497 people
- Sponsor
- Meridian Bioscience, Inc.
Acute Pharyngitis, Acute Laryngitis
Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis
In this observational study insights regarding the tolerability and influence on the quality of life of the topical treatment Ectoin Mund- and Rachenspray compared to Emser Pastillen in patients with acute Pharyngitis/ Laryngitis…
- Trial name
- NCT02160912
- Where
- 8 sites in Germany
- Volunteers
- 95 people
- Sponsor
- Bitop AG
Tonsillitis, Pharyngitis
TELI TON - Telithromycin in Tonsillitis
This is a multinational, randomized (1:1), double blind, double dummy, comparator-controlled, 2 parallel treatment group study in subjects from 6 months to < 13 years of age, with Streptococcus pyogenes tonsillitis/pharyngitis…
- Trial name
- NCT00315042
- Testing
- Telithromycin (HMR3647), Penicillin
- Where
- 5 sites in United States, Argentina and 3 more
- Volunteers
- 314 people
- Sponsor
- Sanofi
Pharyngitis
Efficacy and Tolerability of Ambroxol Lozenge 20 mf in Relieving Pain of Sore Throat in Pat. With Acute/Viralpharyngitis
The purpose of this trial is to investigate efficacy and tolerability of lozenges containing 20 mg a mbroxol hydrochloride (Mucoangin?) relative to lozenges containing placebo and lozenges containing 3 mg benzocaine in relieving…
- Trial name
- NCT00148499
- Testing
- Ambroxol hydrochloride (Mucoangin?), benzocaine
- Where
- 14 sites in Romania, Ukraine
- Volunteers
- 751 people
- Sponsor
- Boehringer Ingelheim
Pharyngitis Acute, Pharyngitis
Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges
This study aims to evaluete of tthe efficacy and safety of using different doses of the drug Grammidin with anesthetic, a metered dose topical spray, in the treatment of acute infectious and inflammatory pharyngeal diseases.
- Conditions
- Pharyngitis Acute, Pharyngitis, Nasopharyngitis, Exacerbation of Chronic Pharyngitis
- Trial name
- NCT06843018
- Testing
- Grammidin with anesthetic, Septolete Total
- Where
- 12 sites in Russia
- Volunteers
- 300 people
- Sponsor
- Valenta Pharm JSC
Group A Streptococcal Infection
Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Patients With Acute Pharyngitis.
Participants who meet the eligibility criteria and who consent to participation or whose parents/legal guardian consent to their participation, will be enrolled in the study for a period of up to 14 days.
- Trial name
- NCT03171350
- Testing
- ellume.lab Group A Streptococcus Test
- Where
- 8 sites in Australia
- Volunteers
- 132 people
- Sponsor
- Ellume Pty Ltd
Pharyngitis
A Study of Flurbiprofen 8.75 mg Lozenge in Patient With Pharyngitis
The purposes of this study is to demonstrate the analgesic efficacy of flurbiprofen 8.75 mg lozenge compared to its vehicle lozenge and to demonstrate the safety of the flurbiprofen lozenge throughout the course of treating sore…
- Trial name
- NCT01049334
- Testing
- Flurbiprofen
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Reckitt Benckiser LLC
Sore Throat
Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief
Prospective, randomized, double-blind, placebo-controlled, multicentre clinical trial to assess the efficacy and tolerability of natural seawater based throat spray among adult patients with acute sore throat.
- Trial name
- FLASH (NCT03369132)
- Testing
- Angiflash
- Where
- 16 sites in Czechia
- Volunteers
- 360 people
- Sponsor
- Laboratoire de la Mer
Tonsillopharyngitis, Respiratory Tract Infection Viral
Safety and Efficacy of the Sore Throat Lozenges to Treat Acute Sore Throats
Aim of this study is to investigate safety and efficacy of A. Vogel Sore throat lozenges for the treatment of of acute sore throats
- Trial name
- NCT04139681
- Testing
- A. Vogels Sore Throat lozenges
- Where
- Bulgaria
- Volunteers
- 74 people
- Sponsor
- A. Vogel AG
Acute Viral Pharyngitis
Ectoin® Lozenges in the Treatment of Acute Viral Pharyngitis
This a comparative, open label, parallel group, non interventional study which compares the tolerability and influence of Ectoin containing Lozenges to saline solution and lozenges containing hyaluronic acid for the treatment of…
- Trial name
- NCT02669446
- Testing
- Medical devices, traditional household remedy
- Where
- 4 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Bitop AG
Acute Viral Pharyngitis
Application of Ectoin Containing Lozenges (EHT02) in Patients With Acute, Viral Pharyngitis.
The goal of this non-interventional study is to investigate the safety, efficacy and tolerability of Ectoin Lozenges Honey Lemon (EHT02) compared to lozenges containing hyaluronic acid and islandic moss in the treatment of acute…
- Trial name
- NCT03943186
- Testing
- Ectoin Lozenges Honey Lemon, Hyaluronic Acid/Icelandic moss Lozenges
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Bitop AG
Acute Sore Throat
Benzydamine in Sore Throat Pain Relief (BePaiR Study)
The aim of this study is to generate new clinical data about the speed of relief provided by a single application of Benzydamine hydrochloride 0,3% oromucosal spray vs Benzydamine hydrochloride 3 mg lozenges mint flavour.
- Trial name
- BePaiR (NCT04941976)
- Testing
- 0.3% benzydamine hydrochloride spray oromucosal solution, Single 3 mg lozenge of benzydamine hydrochloride (mint flavour)
- Where
- 17 sites in Hungary, Poland and 1 more
- Volunteers
- 356 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A