Clinical trials: Soft Tissue Defects
Reconstruction of Upper Body Soft Tissue Defects
Reconstruction by Thoracodorsal Artery Perforator Flap in Patients With Upper Body Soft Tissue Defects
evaluation of versatility and reliability of thoracodorsal artery perforator flap by assessment of recipient site reach
- Trial name
- NCT07734337
- Testing
- Reconstruction
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Algeness"
A single-center clinical study of the efficacy and safety of the medical device "Algeness subdermal implant based on agarose (Ghimas SpA/Ghimas SpA, Italy) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Soft Tissue Volume Loss, Lipoatrophy
- Trial name
- NCT07618468
- Testing
- Algeness Subdermal Implant (Agarose)
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Coverage of Soft Tissue Defects
Perforator Mapping and Optimizing Design of the Lateral Arm Flap
The goal of this clinical trial is to optimize the design of lateral arm flap. Colored duplex will be done for all Participants and compared to intra operative findings.
- Trial name
- NCT05718635
- Testing
- coloured duplex, supra facial dissection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aswan University
Finger Injuries
Reconstructive of Multiple-digit Soft-tissue Defects Using Regional Dorsal Digital Flaps
Reconstruction of soft-tissue defects in multiple digits poses a significant challenge. This article reports simultaneous reconstruction of multiple small-to-moderate soft-tissue defects using regional dorsal digital island flaps…
- Trial name
- NCT03717220
- Testing
- flap transferring
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Defect in Alveolar Ridge
Novel Technique Versus Conventional Subepithelial Connective Tissue Graft in Treatment of Ridge Contour Defects
The aim of the study is to clinically and radiographically evaluate and compare two techniques to augment soft tissues: the conventional subepithelial connective tissue graft technique and a novel denuded interpositional pedicled…
- Trial name
- NCT06435780
- Testing
- DIPRF
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Misr International University
Tethered Spinal Cord, Including Thickened Filum, Lipomas, Myelomeningocele and Meningocele
Inflammatory Response in Children Suffering From Tethered Cord
Embryologic phenomenons that lead to dysraphisms are known, but pathophysiology remains questioned. It is supposed not to be a simple mechanistic dysfunction, and other biological phenomenons are implied in spinal cord damaging.
- Trial name
- TETHERIC (NCT07611058)
- Testing
- CSF sampling during surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille
Mucogingival Defects, Pontic Site Development
Pontic Site Development With or Without Fixed Partial Denture
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects.
- Conditions
- Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
- Trial name
- Pontic Site (NCT07535060)
- Testing
- Connective Tissue Graft (CTG)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hand Injuries
Reconstruction of Hand Soft Tissue Defects
Evaluation of distally based posterior interosseous artery flap in reconstructing hand soft tissue defects that may result from trauma, extensive burns, tumor resection or congenital deformities.
- Trial name
- NCT05218252
- Testing
- Posterior interosseous artery flap
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
Pituitary Tumor, Meningioma
Long-Term Longitudinal QoL in Patients Undergoing EEA
This is a prospective longitudinal study to access postoperative 2-year quality of life in patients who undergo endonasal endoscopic approach surgeries of the skull base.
- Conditions
- Pituitary Tumor, Meningioma, Rathke Cleft Cysts, Chordoma
- Trial name
- NCT04087902
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Open Wound of Lower Limb
Comparison of Distally Based Sural Artery and Supramalleolar Flap for Coverage of Dorsum of Foot and Ankle Defects
Our main aim for this study was to evaluate the long-term outcome comparisons between sural artery and Supramalleolar flap in the reconstruction of extensive defects of non-weight bearing regions of foot and ankle.
- Trial name
- NCT05027542
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Abeer Musaddiq
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Reconstruction of Head Soft Tissue Defects, Reconstruction of Neck Soft Tissue Defects
Reliability and Versatility of Supraclavicular Artery Flap in Reconstruction of Head and Neck Soft Tissue Defects
This is a case series study conducted at plastic surgery department Sohag University including 20 patients The aim of this thesis is to evaluate reliability and versatility of Supraclavicular artery flap in the reconstruction of…
- Trial name
- NCT05727150
- Testing
- Reconstruction of Soft tissue defects of head and neck by Supraclavicular artery flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Burn Injury, Soft Tissue Injury
Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin Defects
The purpose of this study is the evaluation of the safety of autologous tissue-engineered dermal substitutes "denovoDerm" (first arm) and dermo-epidermal skin substitutes "denovoSkin" (second arm) transplanted onto the wound bed…
- Conditions
- Burn Injury, Soft Tissue Injury, Skin Necrosis, Scars
- Trial name
- NCT02145130
- Testing
- denovoDerm, denovoSkin
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Dental Implantation, Peri-Implant Soft Tissue Deficiency
Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects
Peri-implant soft-tissue defects will be treated with either a volume-stable collagen matrix (VCMX; test group) or an autogenous connective tissue graft (CTG; control group) following implant placement in patients with a single…
- Conditions
- Dental Implantation, Peri-Implant Soft Tissue Deficiency, Soft Tissue Augmentation
- Trial name
- NCT07782125
- Testing
- Connective tissue graft, Volume-stable collagen matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
Third Degree Burn, Burns
StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects
This pilot Phase I/II clinical study will be conducted at up to three clinical sites. This is an open-label, randomized, comparative study with a maximum of fifteen (15) patients, each with skin defects.
- Conditions
- Third Degree Burn, Burns, Wound Infection, Degloving Injury
- Trial name
- NCT00618839
- Testing
- StrataGraft Skin Tissue, Cadaver allograft
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Soft Tissue Injuries, Trauma
Acellular Adipose Tissue (AAT) for Soft Tissue Reconstruction
Although other methods (e.g., autologous fat transfer, dermal-/collagen-based fillers) for soft tissue reconstruction exist, each has distinct disadvantages leaving room for improvement in this treatment area.
- Trial name
- NCT03544632
- Testing
- Acellular Adipose Tissue (AAT)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Birth Defects, Pregnancy
Uterine Fibroid Pregnancy Registry
The Uterine Fibroid Pregnancy Registry is a USA and European-based registry designed to monitor pregnancies in women with uterine fibroids in order to 1.
- Conditions
- Birth Defects, Pregnancy, Uterine Fibroids
- Trial name
- NCT00232713
- Volunteers
- 2,360 people
- Sponsor
- Syneos Health
Soft Tissue Defects, Perforator Flap
Perforator Pedicled V-Y Advanced Flaps for Coverage in the Lower Limbs
Repair of soft tissue defects with hardware exposing in the lower limbs was considered as a severe challenge for plastic surgeons in reconstructive surgery.
- Trial name
- NCT06885450
- Testing
- Perforator Pedicled Flaps
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Leg Coverage Defects
Medial Tab Flap for Soft Tissue Defects of the Leg
Selecting the right technique for lower limb soft tissue reconstruction is a therapeutic challenge. Despite having several reconstruction options, it's important to choose a technique that is effective and with the least possible…
- Trial name
- NCT05864963
- Testing
- Medial tab-type fasciocutaneous flap
- Where
- Colombia
- Volunteers
- 64 people
- Sponsor
- Fundación Campbell
Soft Tissue Defects, Soft Tissue Wounds
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Demonstrate faster tissue coverage of exposed structures using OFM in combination with negative pressure wound therapy (NPWT), versus NPWT alone
- Conditions
- Soft Tissue Defects, Soft Tissue Wounds, Traumatic Soft Tissue Defect
- Trial name
- COVER (NCT07385313)
- Testing
- Myriad™ applied in conjunction with NPWT, NPWT Alone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Aroa Biosurgery Limited