Clinical trials: Socket Preservation, active
Alveolar Ridge Augmentation
PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction
This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the…
- Trial name
- NCT06783660
- Testing
- Peptide-loaded collagen sponge and collagen gel complex, Collagen sponge
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- NIBEC Co., Ltd.
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Wisdom Tooth, Socket Preservation
Application of Alloplastic Bone Graft With Polycaprolactone (PCL) Membrane and ECM-Collagen Membrane on Secondary Socket Healing in Third Molar Surgery.
This study compared two membrane materials: 1. polycaprolactone (PCL) and 2. Extracellular matrix collagen membrane (ECM) as alternative. This is to see how well they prevent bone and gum damage after lower wisdom tooth removal.
- Trial name
- PCL ECM (NCT07834645)
- Testing
- polycarprolactone membrane (PCL membrane), Extracellular matrix collagen (ECM) membrane
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Socket Shield Technique, Concentrated Growth Factors
Immediate Implant Placement Using Socket Shield With CGF
This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic…
- Conditions
- Socket Shield Technique, Concentrated Growth Factors, Immediate Dental Implant Placement, Alveolar Bone Preservation
- Trial name
- CGF (NCT07520526)
- Testing
- Immediate implant placement with Socket Shield Technique and CGF
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Mesh, Healthy Volunteer
Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid
Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell…
- Conditions
- Mesh, Healthy Volunteer, Low Level Laser Therapy, Hyaluronic Acid Gel for Preservation the Extraction Socket
- Trial name
- LLLT vs HA (NCT07205640)
- Testing
- Low-Level Laser Therapy, Hyaluronic Acid (HA)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Radiographic Evaluation, Bone Density
Effect of Thymoquinone 0.2% Gel on Bone Density, Bone Width, and Socket Preservation After Tooth Extraction
This study aims to evaluate the clinical and radiographic effects of 0.2% Thymoquinone gel on bone density, bone width, and socket preservation after tooth extraction.
- Conditions
- Radiographic Evaluation, Bone Density, Bone Width, Socket Preservation
- Trial name
- NCT07765745
- Testing
- Gel foam, Thymoquinone gel + gel foam, Nano-formulated 0.2% thymoquinone gel + gel foam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
L-PRF, Dental Implants
Evaluation of the Effect of Leucocyte Platelet-Rich Fibrin (L-PRF) Technique Applied in Post-extraction Sockets Before Placement of Dental Implants
Aim of study: The application of L-PRF membrane in post-extraction sockets outmatches the use of a) allograft covered with a collagen fleece b) allograft combined with L-PRF membrane c) natural healing, with reference to bone…
- Conditions
- L-PRF, Dental Implants, Osseointegration, Alveolar Bone Grafting
- Trial name
- NCT07387913
- Testing
- Allograft and collagen membrane, Allograft and L-PRF membrane, L-PRF
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Socket Preservation, Implant-supported Single Crowns
Hyaluronic Acid and Polynucleotides in Ridge Preservation
The aim of this study is to test the use of a bovine-derived bone graft combined with a polynucleotides-rich hyaluronic acid (PNHA) gel for the preservation of the bone after a tooth extraction (alveolar ridge preservation) and…
- Conditions
- Socket Preservation, Implant-supported Single Crowns, Hyaluronic Acid, CAD-CAM
- Trial name
- P-005 (NCT07099846)
- Testing
- regeneration of post extraction socket with biomaterials
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Tooth Loss
Influence of Healing Time on the Outcomes of Alveolar Ridge Preservation in Periodontally Compromised Extraction Sockets
The goal of this clinical trial is to histologically, clinically, and radiographically evaluate the healing sequelae of periodontally compromised extraction sockets grafted with Bio-Oss Collagen® at 3 and 6 months following tooth…
- Trial name
- NCT06654141
- Testing
- Alveolar ridge preservation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Extraction Socket Healing, Extraction, Tooth
The Effect of Collagen In Tooth Extraction Procedures
This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the…
- Trial name
- NCT07270510
- Testing
- Collagen Matrix soft tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Socket Preservation
Evaluation of Dentin Graft and I-PRF With and Without Vitamin C for Post-extraction Socket Preservation
The aim of the study is to evaluate radiographic ridge width change following autogenous demineralized dentin graft (ADDG) and i-PRF addition with and without vitamin C (AA) for post extraction socket preservation.
- Trial name
- NCT06569264
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft and i-PRF, Alveolar ridge preservation using vitamin C with dentin graft and i-PRF
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation
The Local Effect of Vitamin K2 on Bone Remodeling in Socket Preservation
This study is a randomized controlled trial comparing the effects of socket grafting with crushed vitamin K2 (menaquinone)capsules versus no grafting on bone density and socket dimensions following tooth extraction.
- Trial name
- NCT06707909
- Testing
- Menaquinone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alveolar Bone Loss, Periodontal Diseases
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation
Tooth extraction triggers a cascade of biological events mediated by the local inflammatory response following surgical intervention and by the loss of masticatory stimulation to the periodontium.
- Conditions
- Alveolar Bone Loss, Periodontal Diseases, Periodontal Bone Loss, Periodontal Atrophy
- Trial name
- NCT07573761
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Alveolar Socket Preservation
Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used.
- Trial name
- Alb-PRF (NCT06757218)
- Testing
- empty socket, Autogenous Dentin Graft with Platelet Rich Fibrin, Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Alveolar Bone Loss, Sinus Floor Augmentation
Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiographical Study
This research aims to investigate the influence of alveolar ridge preservation, after extraction of maxillary posterior teeth, on the potential need of sinus floor augmentation procedures (that include lateral or crestal sinus…
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- NCT07526129
- Testing
- Alveolar ridge preservation using bony biomaterials
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Socket Preservation
Sticky Bone vs Xenograft With Cross-linked Hyaluronic Acid in Socket Preservation
The present study aimed to evaluate clinical and radiographic outcomes of sticky bone in comparison to crosslinked hyaluronic acid mixed with xenograft in alveolar ridge preservation.
- Trial name
- NCT06983015
- Testing
- sticky bone, xenograft mixed with cross-linked hyaluronic acid
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Alveolar Bone Loss, Dental Implant
Socket Preservation - A Randomized Clinical Implementation in a Student Setting
Preserving the ridge dimension after tooth extraction aims to avoid the need for bone augmentation procedures before implant placement.
- Conditions
- Alveolar Bone Loss, Dental Implant, Bone Augmentation
- Trial name
- NCT06539299
- Testing
- Socket Preservation
- Volunteers
- 51 people
- Sponsor
- Sigmund Freud PrivatUniversitat