Clinical trials: Smoking Cessation, open to volunteers
Chronic Obstructive Pulmonary Disease (COPD), Smoking
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Idiopathic Pulmonary Fibrosis (IPF)
- Trial name
- NCT01776398
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Smoking Cessation, Nicotine Replacements Therapy
A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers
The objective of the study is to evaluate the relief of momentary urge to smoke at pre-specified early post-dose time points after administration of Nic ODT compared to Placebo ODT.
- Trial name
- Zippy PD (NCT07893158)
- Testing
- Nicotine Mint Oro Dispersible Tablet (Nic ODT)
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Lung Cancer (Diagnosis), Smoking Cessation
Impact of Lung Cancer Screening With Chest Scans Combined With Coaching on Smoking Cessation in Heavy Smokers
Lung cancer is common and serious, but when detected early, the chances of recovery are significantly better. Tobacco use is the leading cause.
- Conditions
- Lung Cancer (Diagnosis), Smoking Cessation, Lung Neoplasm
- Trial name
- NCT07860359
- Testing
- Image-Based Counseling, Smoking Cessation Coaching, Low-Dose Chest Computed Tomography (LDCT)
- Where
- Switzerland
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
E Cigarette Use
A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes
This study aims to evaluate the effects of a six-week behavioral circuit breathing training intervention on smoking cessation and respiratory function compared with diaphragmatic breathing training and usual daily activities
- Trial name
- NCT07882407
- Testing
- Circuit Breathing Intervention, Diaphragmatic Breathing
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Smoking Cessation
ChatGPT-Supported Text Messaging Program for Smoking Cessation
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree.
- Trial name
- NCT07079306
- Testing
- BeFree+Bot, BeFree
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- George Washington University
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Smoking Cessation
Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers
Pilot randomized controlled trial evaluating feasibility, acceptability, and trial-readiness of the new app compared with the existing print booklets and the NCI SmokefreeTXT en Español program.
- Trial name
- NCT07754448
- Testing
- Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking Cessation, Tobacco Smoking
Trauma-Informed Care for Smoking Cessation for Pregnancy
Trauma-informed approaches have been shown to support recovery from other substance use disorders and involve four key elements: (1) Realizing the prevalence of trauma and pathways to recovery, (2) Recognizing symptoms of trauma…
- Conditions
- Smoking Cessation, Tobacco Smoking, Tobacco Use Cessation, Smoking Reduction
- Trial name
- NCT07129590
- Testing
- Expired carbon monoxide (CO), Interviews, Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Former Smoker, Non-Smoker
Vaped Phenanthrene
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former…
- Trial name
- NCT07134426
- Testing
- D10-phenanthrene
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Mobile Phone-Based Smoking-Cessation Intervention for Smoking Parents
This study aims to explore the feasibility and preliminary effectiveness of a mobile phone-based intervention tailored specifically for smoking parents.
- Trial name
- NCT06570122
- Testing
- 5A's/5R's advice, Health warning leaflet, AI-powered chatbot support
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Smoking, Smoking Cessation
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit
- Trial name
- NCT06693700
- Testing
- Indoor Air Quality Monitor AirGradient ONE
- Where
- 8 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking Cessation
Health Communications for Adults Smoking Nondaily
The goal of this study is to develop smoking health risk messaging targeted to adults who smoke some days, but not smoke every day (nondaily).
- Trial name
- NCT07296848
- Testing
- Targeted Smoking Messages
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Bethany Shorey Fennell, PhD
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation
Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation
No published studies to date have evaluated the combined impact of varenicline and oral nicotine replacement therapy (NRT) on smoking cessation in a randomized trial.
- Trial name
- COMBOII (NCT07099638)
- Testing
- Varenicline (VAR), Nicotine lozenge (NRT), Smartphone intervention with adherence components (COMBO-A)
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Smoking Cessation Counseling Ability and Practice
Evaluating the Impact of CONNECT in a Multilingual Population
This study aims to broaden the reach of the lung cancer screening (LCS) CONNECT program (NCT04149249, NCT06213532), by developing a version of the program to be available to multilingual communities.
- Conditions
- Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
- Trial name
- CONNECT-ML (NCT07111936)
- Testing
- CONNECT Intervention for multilingual populations, Saliva Sample, Interview
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
Rural Smoking Cessation
Understanding ways to help people who live in rural areas quit smoking is a public health priority. quitting smoking among rural people who smoke is a critical public health concern.
- Trial name
- NCT06584929
- Testing
- Nicoderm CQ nicotine patch, Nicorette Nicotine Lozenges
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Smoking Cessation
My Path to Quit Tobacco
The overarching goal of this program of research is to reduce smoking-related health disparities by increasing smoking cessation among Black adults.
- Trial name
- NCT07419425
- Testing
- Nicotine patch, Quitline Counseling Phone Calls, Counseling Sessions
- Where
- 5 sites in United States
- Volunteers
- 1,550 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use Cessation
VergeRx for Smokers Not Ready to Quit
This study uses a factorial optimization experiment to identify which treatment components help adults who smoke and are not ready to quit in the next 30 days (smokers not ready to quit, or SNRTQ) achieve smoking cessation.
- Trial name
- NCT07693660
- Testing
- VergeRx, SmokefreeTXT, NRT Lozenge (Combination)
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking Cessation
American Indian Smokefree Native RCT
The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.
- Trial name
- NCT06544811
- Testing
- Smoking Cessation Program, Cultural Smoking Cessation Program
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota