Clinical trials: Smoking
Smoking Cessation
Capitalizing on a Teachable Moment to Promote Smoking Cessation
The purpose of this study is to develop and test a self-help smoking cessation treatment for patients receiving a lung cancer screening computed tomography (CT) scan.
- Trial name
- NCT02276664
- Testing
- Self-Help (SHI), Usual Care (UC)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
PASSIVE SMOKING ,, RESPIRATORY SYSTEM MECHANICS,
Effects Of Passive Smoking On The Respiratory System Mechanics Of Healthy Non-Smokers In Different Body Positions
The study will examine changes in the respiratory system mechanics and in respiratory physiology after exposure of subjects to passive smoking.
- Trial name
- NCT02171871
- Testing
- exposed to a smoking environment
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Smokers
Improving Medication Compliance and Smoking Cessation Treatment Outcomes for African American Smokers
Little is known about the support needed to improve compliance with Chantix for smoking cessation. This is a two arm pilot study of African American smokers to provide varying levels of side effect management and compliance…
- Trial name
- NCT00781599
- Testing
- Chantix, Adherence Counseling, Standard Counseling
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Nikki Nollen, PhD, MA
Hypertension, Hyperlipidemia
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment…
- Conditions
- Hypertension, Hyperlipidemia, Diabetes, Smoking
- Trial name
- NCT01420016
- Testing
- Prioritized Clinical Decision Support
- Volunteers
- 7,914 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Lung Cancer
The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy
This protocol pertains specifically to the prospective lung squamous cell carcinoma pre-malignant lesion (PML) cohort that will form a primary study group for the Lung Pre-Cancer Atlas.
- Trial name
- NCT03881098
- Testing
- Bronchoscopies, Sputum Sample, Venipuncture
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of Colorado, Denver
Lung Cancer
S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
RATIONALE: A program that includes bupropion may be more effective in helping early-stage lung cancer patients to quit smoking. It is not yet known if a program to quit smoking is more effective with or without bupropion.
- Trial name
- NCT00032084
- Testing
- smoking cessation intervention, bupropion hydrochloride, nicotine
- Where
- 176 sites in United States, Puerto Rico
- Volunteers
- 10 people
- Sponsor
- SWOG Cancer Research Network
Smoking, Smoking Cessation
Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
The purpose of this randomized controlled trial is to assess the efficacy of Actívatexto (Aim 1) and the mediators of the presumed treatment effect (Aim 2) among Latino adults who smoke.
- Conditions
- Smoking, Smoking Cessation, Physical Inactivity
- Trial name
- NCT06926608
- Testing
- Actívatexto, Decídetexto
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Rochester
Smoking Cessation
Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers
Pilot randomized controlled trial evaluating feasibility, acceptability, and trial-readiness of the new app compared with the existing print booklets and the NCI SmokefreeTXT en Español program.
- Trial name
- NCT07754448
- Testing
- Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea, Smoking
Effects of Obstructive Sleep Apnea and/or Cigarette Smoking on Endothelial Function
The hypothesis of this study is that either obstructive sleep apnea (OSA) or cigarette smoking (CS) exposure would produce oxidative stress and inflammation leading to endothelial injury, and the combined exposure would be…
- Trial name
- NCT00957463
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Nicotine Dependence, Cigarettes
The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products
This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.
- Trial name
- ENDS-Switch (NCT03492463)
- Testing
- Nicotine patch, E-cigarettes, Non-nicotine e-cigarettes
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Smoking Cessation
Safety and Pharmacodynamics of SEL-068 Vaccine in Smokers and Non-Smokers
The purpose of this study is to evaluate the safety and pharmacodynamics of SEL-068. Increasing subcutaneous doses of SEL-068 will be administered to healthy non-smoker and smoker volunteers.
- Trial name
- NCT01478893
- Testing
- SEL-068, Saline
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Selecta Biosciences, Inc.
Smoking
Tobacco Constituents and Biomarkers
This proposal addresses several research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products as mandated by the Family Smoking Prevention and Tobacco Control Act.
- Trial name
- NCT04090606
- Testing
- FTC Method Smoking Regimen, Massachusetts Method Smoking Regimen, Health Canada Intense Smoking Regimen
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma
Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer
This randomized phase II trial studies the side effects and how well modestly reduced-dose intensity-modulated radiation therapy (IMRT) with or without cisplatin works in treating patients with oropharyngeal cancer that has…
- Conditions
- Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma, Stage IVC Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT02254278
- Testing
- Cisplatin, IMRT 6 weeks, IMRT 5 weeks
- Where
- 222 sites in United States, Canada and 2 more
- Volunteers
- 316 people
- Sponsor
- NRG Oncology
Tobacco Use Cessation
Evaluating the Feasibility and Efficacy of a Real-time Smoking Intervention Using Wearable Technology
This study will use wearable technology to test the feasibility and efficacy of delivering a novel real-time smoking intervention to improve standard tobacco treatment.
- Trial name
- NCT04172623
- Testing
- Real-Time Smoking Intervention, Standard Treatment
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Yale University
Smoking Cessation
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
This randomized controlled trial will compare the effectiveness of two models of post-discharge tobacco cessation treatment for adult smokers admitted to 3 U.S. hospitals.
- Trial name
- HH4 (NCT03603496)
- Testing
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Where
- 3 sites in United States
- Volunteers
- 1,416 people
- Sponsor
- Massachusetts General Hospital
Sexual Behavior, Alcohol Drinking
Adolescent Safer Sex Social Network Intervention
Social networks are thought to hold the potential for shaping behavior on the grounds that social and situational factors more strongly influence behavior than do personality variables.
- Conditions
- Sexual Behavior, Alcohol Drinking, Marijuana Smoking
- Trial name
- NCT00107562
- Testing
- Adolescent Safer Sex Social Network Intervention
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Exposure to Secondhand Smoke in Neonatal Infants
Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' Homes
A randomized, controlled, parallel group design will be used to test whether a Secondhand Smoke Exposure program initiated in the hospital and completed in the home using motivational interviewing plus motivational incentives…
- Trial name
- NCT01726062
- Testing
- Motivational Interviewing plus Incentives, Conventional Care (CC)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Use
E-Cigarette and Cigarette Nicotine Delivery and Abuse Liability in Cigarette Smokers and Dual Users
The FDA has shown clear interest in strategies that will reduce the public health burden of tobacco use. One proposed strategy includes banning the sale of fully nicotinized cigarettes and only allowing VLNCs (Very Low Nicotine…
- Trial name
- NCT03943706
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking, Smoking Cessation
Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic Randomised Controlled Trial
Objective: Our study aims to evaluate the effectiveness of the "STOP" (Sevrage Tabagique à l'aide d'Outils dédiés selon la Préférence: Smoking Cessation using preference-based tools) intervention, a preference-based smoking…
- Trial name
- STOP (NCT04654585)
- Testing
- The STOP intervention, Standard Care
- Where
- 15 sites in France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Société de Formation Thérapeutique du Généraliste - Recherche