Clinical trials: Smokeless Tobacco
Tobacco Use Cessation
Tobacco Cessation Via Doctors of Chiropractic
The purpose of the study is to develop an office-based tobacco intervention for chiropractic patients.
- Trial name
- NCT00386945
- Testing
- Brief counseling (Ask, Advise, Arrange)
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Oregon Research Institute
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontitis and Mortality: 30-year Cohort Study From Sweden
Smoking and dual using associated with poor periodontal health.
- Trial name
- NCT03918902
- Testing
- Qestinnaires
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Smoke Exposure, Smokeless Tobacco
Effect of Passive Smoking on Functional Capacity, Cognition and Academic Performance in Primary School Children
This is an observational study that aims to understand the effects of passive smoking (secondhand smoke exposure) on children's health and development.
- Trial name
- NCT06723470
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Egyptian Chinese University
Tobacco Use Cessation
Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention
The purpose of the study is to compare two methods for providing brief dental office-based interventions designed to help patients quit either cigarette smoking or smokeless tobacco use, and to compare these two dental…
- Trial name
- NCT00384254
- Testing
- 5 A, 3 A
- Where
- United States
- Volunteers
- 2,177 people
- Sponsor
- Oregon Research Institute
Tobacco Dependence
Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
To test if smokeless tobacco is more effective than nicotine buccal tablets in smoking cessation compared with a control group with low dose nicotine patches.
- Trial name
- NCT00313105
- Testing
- Smokeless tobacco (Oliver Twist pellets), smoking cessation counseling
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Smoking Behaviors
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand
To explore consumer responses to the announcement and implementation of new modified risk claims for Copenhagen and General Snus (brands of smokeless tobacco (ST) products) using a series of complementary and innovative research…
- Trial name
- NCT07102082
- Testing
- Modified Risk - None, Modified Risk Claim
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Tobacco Use Disorder, Nicotine Dependence
Novel Determinants and Measures of Smokeless Tobacco Use: Study 2
The research project will determine the level of nicotine in ST products that will lead to the greatest reduction in toxicant exposure
- Trial name
- NCT01067599
- Testing
- Low nicotine, Medium nicotine, High nicotine
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Urine Detectable Acute and Chronic Diseases
A Comparative, Controlled Study to Evaluate the Lay User Accuracy and Performance of the Dip Home-Based Dipstick Analyzer
The Dip Home-Based Dipstick Analyzer (henceforth HBDA) is composed of a kit and a smartphone application. The device will be provided to the subject in a simulated home-use environment.
- Trial name
- NCT04466774
- Testing
- Dip Home-Based Dipstick Analyzer, Urine analysis predicate device for professional user
- Where
- 3 sites in United States
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Healthy.io Ltd.
Tobacco Use Cessation
A Multi-Media Approach to Partner Support in Smokeless Tobacco Cessation (UCare-ChewFree)
In an earlier study, the investigators developed a guidebook that taught women supportive behaviors to help their husbands/partners quit smokeless tobacco.
- Trial name
- NCT01885221
- Testing
- Multimedia Support Intervention
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Tobacco Use, Tobacco Smoking
Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]
To pilot test the appeal of non-tobacco oral nicotine products in cigarette smokers, smokeless tobacco users, and oral nicotine users.
- Conditions
- Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
- Trial name
- NCT05030194
- Testing
- Electronic Cigarette, Oral Nicotine Pouch
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation, Harm Reduction
In-vivo Extraction of Lead, Cadmium and Tobacco Specific Nitrosamines From Swedish 'Snus' in Regular Snus Users
In an open label, randomized, two-way cross-over study, 32 male healthy regular snus users will be given repeated doses of four different types of portion snus: "General", "Catch", "Catch Mini" and "Catch Dry Mini".
- Trial name
- SMWS03 (NCT01838473)
- Testing
- Buccal Administration of nicotine
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Contract Research Organization el AB
Smoking
Smoking Cessation in Groups and With Tobacco Pastils
The purpose of this trial is to examine if smokeless tobacco combined with group support might increase smoking cessation rate compared with groups support in smokers.
- Trial name
- NCT00265460
- Testing
- Oliwer Twist smokeless tobacco (tobacco)
- Where
- Denmark
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Urinary Tract Infection, Kidney Failure
Healthy.io Method Comparison & User Performance Study
The objectives of the Healthy.io Method Comparison and User Performance Study are: 1. To evaluate the performance of Dip.io Device in comparison to the ACON U500 Mission® U500 Urine Analyzer. 2.
- Conditions
- Urinary Tract Infection, Kidney Failure, Diabetes
- Trial name
- NCT02785445
- Testing
- Dip.io Home Based Dipstick Analyzer, ACON U500 Mission® U500 Urine Analyzer
- Where
- 2 sites in United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Healthy.io Ltd.
Tobacco Use Disorder
Nicotine Lozenge to Reduce Smokeless Tobacco Use
Smokeless tobacco (ST), which includes both chewing tobacco and snuff, has as many health risks associated with its use as cigarettes.
- Trial name
- NCT00218283
- Testing
- Nicotine Lozenge, Behavioral Counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking, Smoking Cessation
A Test of Short and Long Term Naturalistic Outcomes of Smokers Who Sample Smokeless Tobacco
This nationwide telephone and mail- based research study will recruit 1,400 cigarette smokers who are not motivated to quit to test the effects of a marketed oral, non-combustible smokeless tobacco product on cigarette smoking…
- Trial name
- NCT01509586
- Testing
- Potentially Reduced Exposure Product (PREP): a smokeless, spit-free tobacco product
- Where
- United States
- Volunteers
- 1,236 people
- Sponsor
- Medical University of South Carolina
Tobacco Toxicant Exposure
Metabolism of Deuterated NNN in Smokeless Tobacco Users
The purpose of this study is to better understand how people break down a tobacco specific cancer-causing toxin called N'-nitrosonornicotine (NNN) that is present in smokeless tobacco and cigarettes.
- Trial name
- NCT02414477
- Testing
- Deuterated NNN
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Participants will be randomly assigned (like the flip of a coin) to one of the two groups after completing the baseline survey. Participants have a 50% of being in either the #EnufSnuff.TXT intervention group or the Enough Snuff…
- Trial name
- NCT04315506
- Testing
- #EnufSnuff.TXT Intervention, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Duke University
Psoriasis, Type 2 Diabetes Mellitus
Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial.
The primary purpose of this study is to determine if sitagliptin (Januvia®) improves psoriasis severity after 16 weeks of treatment in 20 participants with both psoriasis and type 2 diabetes mellitus.
- Trial name
- DIP (NCT01991197)
- Testing
- Sitagliptin, Gliclazide
- Where
- 2 sites in Ireland
- Volunteers
- 20 people
- Sponsor
- University College Dublin
Smoking Cessation, Smokeless Tobacco
In-vivo Extraction of Pb, Cd andTSNA From Swedish Snus
In an open label, randomized, two-way cross-over study, 32 male healthy regular snus users will be given repeated doses of four different types of portion snus: "General", "Catch", "Catch Mini" and "Catch Dry Mini".
- Conditions
- Smoking Cessation, Smokeless Tobacco, Harm Reduction
- Trial name
- SMWS03 (NCT01249339)
- Testing
- Buccal Administration of nicotine
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Contract Research Organization el AB
Cigarette Smoking
Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus
To evaluate selected biomarkers of tobacco exposure and biomarkers of harm and assess quality of life measures in smokers randomly switched from their usual brand of cigarette to one of three test products: (1) a tobacco-heating…
- Trial name
- QoL (NCT02061917)
- Testing
- Tobacco-Heating Cigarette, Snus (Smokeless Tobacco), Tobacco-Burning Cigarette
- Where
- 5 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company