Clinical trials: Sleep Disruption
Aging, Sleep Restriction
Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism
The overall objectives of the proposed study are to examine the consequences of chronic circadian disruption and chronic sleep restriction on metabolic function in healthy adults.
- Conditions
- Aging, Sleep Restriction, Circadian Disruption
- Trial name
- NCT02171273
- Testing
- Circadian Disruption, Sleep Restriction, Control
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Sleep Fragmentation
Sleep Disruption in Post-operative Patients in the Neurocritical Care Unit
The role of sleep in patients admitted to the intensive care unit is an emerging field of research. There have been studies that show patients in the ICU have poor sleep including sleep fragmentation, multiple arousals, decreased…
- Trial name
- SDPPNCU (NCT02997839)
- Testing
- sleep disruption
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleep Deprivation, Circadian Dysregulation
The Microbiome and Resilience to Sleep and Circadian Disruption
This study is about how sleep loss and being awake at night impacts the ability to think, changes molecules in the blood, and alters the bacteria that live in the gut that typically help keep people healthy.
- Conditions
- Sleep Deprivation, Circadian Dysregulation, Stress
- Trial name
- NCT03747367
- Testing
- Insufficient Sleep, Prebiotic
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Sleep Disorder, Shift Work, Fatigue
Effect of Night Float Call on Sleep and Activity Patterns Among Anesthesia Residents
With increasing awareness about physician fatigue and its effect on patient safety, residency programs are increasingly transitioning to a night float call system.
- Conditions
- Sleep Disorder, Shift Work, Fatigue, Sleep Disturbance
- Trial name
- NCT05043038
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer, Fatigue
The Role of Circadian Rhythms in Cancer-Related Symptoms
Emerging evidence indicates that circadian rhythms may be disrupted following cancer and its treatment, and that circadian rhythm disruption may be an underlying pathophysiological mechanism of cancer- and cancer…
- Conditions
- Breast Cancer, Fatigue, Cognitive Impairment, Sleep
- Trial name
- CHRONO (NCT04401189)
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders
Light Exposure to Treat Sleep Disruption in Older People
The purpose of this study is to test whether shifts in the timing of the biological clock to a later hour (phase delay shifts of the human circadian system) can be produced in response to four successive evenings of light…
- Conditions
- Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
- Trial name
- NCT00427323
- Testing
- light exposure
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Bilateral Salpingo-oophorectomy
Sleep in Women With Bilateral Salpingo-Oophorectomy
The purpose of this research study is the compare objective and subjective sleep characteristics in women who have undergone removal of both ovaries (bilateral salpingo-oophorectomy) before natural menopause compared to women who…
- Trial name
- NCT04565158
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Noise Exposure
Broadband Sound and Sleep
Sound insulation of bedrooms is expensive and typically only granted to residents living close to the airport. We plan to investigate the effects of various aviation noises on sleep under controlled laboratory conditions and to…
- Trial name
- NCT05774977
- Testing
- Aviation Noise Only (AN), Pink noise only, 50 dBA (BN50), Aviation Noise With Earplugs (AN+EP)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Deprivation, Circadian Dysregulation
Cardiometabolic Risk of Shiftwork
The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than day workers, and that the…
- Conditions
- Sleep Deprivation, Circadian Dysregulation, Shift-Work Sleep Disorder
- Trial name
- SW (NCT01264913)
- Testing
- sleep extension & circadian alignment
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago