Clinical trials: Sleep Architecture
Major Depressive Disorder
Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder
In this study, patients with major depressive disorder (MDD) who have insomnia symptom are treated with Seroquel XR in an open-label manner for a 4-week period with repeated measurements of insomnia symptoms and sleep parameters…
- Trial name
- NCT01189318
- Testing
- Quetiapine Fumarate Extended Release
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ewha Womans University
Breathing Disorder During Sleeping, Sleep Habits
Impact of Palatal Expansion and Up-Locker Activator on Sleep and Pharyngeal Dimensions in Children
Objective: The study will aim to compare the effect of palatal expansion with Hyrax and Hyrax combined with Up-Locker on sleep behavior, sleep architecture, quality of life and nasal and pharyngeal airway dimensions, as well as…
- Trial name
- NCT06986343
- Testing
- Hyrax, Hyrax and Uplocker Vacuum Device
- Where
- Colombia
- Volunteers
- 34 people
- Sponsor
- CES University
Short Sleepers, Normal Sleepers
Homeostatic Regulation of Sleep in Short Sleepers
This single-center study targets adults with distinct sleep profiles, divided into three categories: natural short sleepers, characterized by a reduced nocturnal sleep duration; subjects with idiopathic hypersomnia (IH) followed…
- Conditions
- Short Sleepers, Normal Sleepers, Idiopathic Hypersomnia Patients
- Trial name
- HOMEOSHORT (NCT07584538)
- Testing
- Actigraphy, Polysomnographie (PSG 128), TILE test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Post Traumatic Stress Disorder PTSD
The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSD
Participants in this study will have already been enrolled in another research study: Combining Stellate Ganglion Block with Prolonged Exposure for PTSD, NCT05889741.
- Trial name
- NCT07667309
- Testing
- Sleep Profiler Headband
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Autism, Cognition Disorder
The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism
This study will test whether donepezil (Aricept(Registered Trademark)), a drug that is approved by the Food and Drug Administration to treat Alzheimer's disease, can increase rapid eye movement (REM) sleep in children with autism…
- Trial name
- NCT00695136
- Testing
- Donepezil hydrochloride, Increase REM sleep percentage
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Sleep
Effects of Bladder Voiding on Sleep Architecture in Infants
Sleep changes rapidly during the first year of life. Brain maturation is accompanied by sleep consolidation in several episode during day and night (daytime naps and night sleep) and progressive organization during the 24h period…
- Trial name
- MIDESOM (NCT04317677)
- Testing
- Study of the effect of bladder voiding on sleep fragmentation during day and night sleep
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Bipolar Disorder
Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder
Clinical practice indicates that Quetiapine has sedating properties, and its sedative effects may play an important role in restoring quality of sleep in patients with various psychiatric conditions who frequently experience…
- Trial name
- NCT00616889
- Testing
- Seroquel
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Intensive Care Unit Patients
Improving Sleep Quality in ICU Patients
Sleep architecture is deeply altered in intensive care unit (ICU patients). Among factors involved in poor sleep quality are environmental factors, such as light and noise, which are an unavoidable consequence of cares.
- Trial name
- EARS (NCT02292134)
- Testing
- earplug and sleep mask
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Architecture
Microgreens on Sleep
This study aims to investigate the effects of Microgreen use on sleep architecture in athletes. Sleep architecture refers to the structural organization of sleep, including the distribution of non-rapid eye movement (NREM) and…
- Trial name
- GREENSLEEP (NCT07537140)
- Testing
- cabbage for control, microgreen coctail was given orally
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Cold-water Immersion, High Heat Sauna
Thermodynamic Exposure and Sleep in Military Cadets
This pilot study investigates the effects of cold-water immersion, traditional sauna use, and their combination on sleep architecture and psychological health in military cadets.
- Conditions
- Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
- Trial name
- NCT07201935
- Testing
- Cold Water Immersion, High Heat Sauna
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Bipolar Disorder, Depression
An Investigation of the Sleep Architecture and Consequent Cognitive Changes in Olanzapine-Treated Depressed Patients
OBJECTIVES: Primary Objective: To assess the objective (polysomnographic) changes in sleep quality before and after introduction of olanzapine in treatment of patients with depression.
- Conditions
- Bipolar Disorder, Depression, Depressive Disorder
- Trial name
- NCT00520507
- Testing
- Olanzapine
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Queen's University
Parkinson's Disease, Tremor
Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders
The purpose of this prospective, participant-blinded trial is to determine the changes in sleep architecture in a cohort of subjects who have undergone deep brain stimulation (DBS) surgery for treatment of movement disorders such…
- Conditions
- Parkinson's Disease, Tremor, Dystonia
- Trial name
- NCT01169324
- Testing
- Alteration of DBS stimulator settings
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease
Exercise and Sleep in Parkinson's Disease
This study will investigate the impact of two common exercise modalities, cardiovascular and resistance training, on sleep quality and architecture in persons with Parkinson's disease (PD), and whether these potential positive…
- Trial name
- NCT04558879
- Testing
- CT, RT
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Parkinson Disease, Sleep Disorder
Neuromodulation of Sleep Architecture by STN-DBS in Parkinsonian Patients
Sleep disorder is one of the most burdensome non-motor symptoms in Parkinsonian patients. Typical manifestations include RBD, decreased sleep efficiency, decreased slow wave sleep, daytime sleepiness, increased sleep latency and…
- Trial name
- NCT04976569
- Testing
- STN-DBS stimulation pattern change
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Tsinghua University
Sleep Architecture, Sleep Disorders
Sleep, Cognition and Memory Disorder
The increasing incidence of Alzheimer's disease (AD) and related sleep-disorders with the aging of the population is a major issue of public health. The prevalence of sleep disturbances is about 50% in dementia patients.
- Conditions
- Sleep Architecture, Sleep Disorders, Cognitive Impairment
- Trial name
- SCOAL (NCT01650454)
- Testing
- 2 night polysomnography, battery of neuropsychological tests, virtual reality test
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Major Depressive Disorder
Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder
The purpose of this study is to assess the effect of escitalopram on sleep architecture utilizing a prospective design. Hypothesis: Escitalopram will improve REM latency in patients with MDD that have responded clinically to…
- Trial name
- NCT00442481
- Testing
- Escitalopram, A baseline overnight polysomnography (oPSG)
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Sheba Medical Center
Obstructive Sleep Apnea of Child
Factors Correlated With Obstructive Sleep Apnea in Children and Adolescents
Obstructive Sleep Apnea (OSA) is a severe condition of sleep respiratory disorders. It is characterized by partial (hypopnea) or total (apnea) obstruction of the upper airways, negatively affecting the general and oral health of…
- Trial name
- NCT04328402
- Testing
- Polysomnography
- Where
- Brazil
- Volunteers
- 187 people
- Sponsor
- Federal University of Pelotas
Hypoxia, Sleep
Autonomic Activity During Nap Under Hypoxia
Sleeping under hypoxic conditions can impair cognition and autonomic nervous activity. A short daytime nap can modify these changes.
- Conditions
- Hypoxia, Sleep, Healthy
- Trial name
- NAPOXIA (NCT04146857)
- Testing
- Normoxia, Hypoxia 1, Hypoxia 2
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sleep Architecture Under Opioid Medication
Impairment of Sleep and Pattern of Breathing Before and After Opioid Withdrawal in Comparison to Patients Without Opioid Withdrawal
Main of the study is to assess the influence of high-dose opioids on the sleep architecture and patterns of breathing using non-invasive polysomnographic measurements before and after opioid withdrawal in patient who undergo…
- Trial name
- NCT01540890
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ruhr University of Bochum
Chronic Hypercapnic Respiratory Failure
Patients-ventilator Interaction During Sleep: Effect of Humidification System
At present, little data is available in the medical literature regarding the affects of humidification on NIMV efficacy, sleep quality and upper airway symptoms in patients undergoing nocturnal NIMV.
- Trial name
- NCT01038791
- Testing
- heated humidification, heat and moisture exchanger, usual mechanical ventilation without humidification
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna