Clinical trials: Sleep Architecture
Sleep-Disordered Breathing, Sleep Architecture
Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor
Hypothesis: BR's Gen3 DL algorithms, combined with its subxiphoid body sensor, can accurately diagnose OSA, categorize its severity, identify REM OSA and supine OSA, and detect central sleep apnea (CSA).
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Arrhythmia
- Trial name
- NCT06255613
- Testing
- Belun Ring, Belun Cor
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- Belun Technology Company Limited
Autism Spectrum Disorders
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Background: Some children with autism spectrum disorders (ASD) do not have normal sleep cycles. Some of these children spend very little time in the rapid eye movement (REM) stage of sleep.
- Trial name
- NCT01887132
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Apnea, Sleep
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
Multiple clinical studies have indicated that obstructive sleep apnea (OSA), the most common chronic sleep disorder, may affect neurocognitive function, and that treatment for continuous positive airway pressure (CPAP) has some…
- Trial name
- NCT02886156
- Testing
- CPAP, BSC
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Sleep Architecture, Mild Traumatic Brain Injury
Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)
This study will employ cognitive behavioral therapy for insomnia (CBT-I) among individuals with mild traumatic brain injury (mTBI) who experience sleep disturbances.
- Conditions
- Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
- Trial name
- NCT07385105
- Testing
- Cognitive behavioral Therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Focal Epilepsy
Sleep Architecture & Cognition in Focal Epilepsy
Focal Epilepsy (FE) patients and healthy controls will wear an actigraph at home for one week and a home sleep study device at home for one night.
- Trial name
- NCT05794295
- Testing
- Acoustic Stimulation (AS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Sleep-Disordered Breathing, Sleep Architecture
Screening of OSA in Hospitalized Stroke Patients Using BSP
Obstructive sleep apnea (OSA) is prevalent in patients with stroke and has a negative effect on outcomes by predisposing them to recurrent stroke, increasing mortality, and so forth.
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Stroke, Acute
- Trial name
- NCT05466864
- Testing
- Belun Sleep platform
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Sleep, Circadian Rhythm
Dexmedetomidine Trial for Effects on Rhythms, Sleep Architecture, and Biomarker Dynamics in Older Adults
The DEXTER study is a cross-over, double-blind, placebo-controlled pilot research study led by Dr. Peng Li. The goal of this project is to evaluate the safety, feasibility, and biological effects of a single dose of sublingual…
- Trial name
- DEXTER (NCT07800910)
- Testing
- Dexmedetomidine sublingual film
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sleep
Evening Screen Content and Sleep Architecture in Older Adults: Crossover RCT
Title The Effect of Evening Technology Use with Calming vs. Exciting Content on Sleep Architecture in Older Adults: A Crossover Randomized Controlled Trial Background The study explores how evening use of digital devices with…
- Trial name
- NCT07001514
- Testing
- Calming digital content, Exciting Digital Content, Non-digital book reading
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Insomnia
Alternative Dosing Regimens in the Pharmacotherapy of Insomnia
The purpose of this study is to evaluate whether drug efficiency of zolpidem and amitriptyline can be conditioned according to learning theory in patients with primary insomnia.
- Trial name
- ALPHASOM (NCT02139098)
- Testing
- Amitriptyline, Zolpidem
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Philipps University Marburg
Sleep Disorders
Does Melatonin Restore Sleep Architecture in Autistic Children
Although behavioral disorders origins in autistic children are still unclear, they seem to be influenced by sleep disorders. Results of studies performed on sleep quality in autistic children showed a high prevalence of sleep…
- Trial name
- SOMELIA (NCT01993251)
- Testing
- melatonin
- Where
- 5 sites in France
- Volunteers
- 26 people
- Sponsor
- Hospices Civils de Lyon
Mechanically Ventilated ICU Patients
The Effect of Sodium Oxybate on Sleep Architecture
The purpose of this study is to determine what effect sodium oxybate has on the functions of sleep in mechanically ventilated, critically ill patients hospitalized in an intensive care unit.
- Trial name
- NCT00744393
- Testing
- sodium oxybate
- Where
- United States
- Sponsor
- Tufts Medical Center
Schizophrenia, Insomnia
Trial Evaluating Paliperidone Extended-Release (ER) Tablets Versus Placebo on Sleep in Schizophrenia Patients
The primary objective of this study is to evaluate the amelioration of the sleep architecture of patients with schizophrenia and schizophrenia-related insomnia, treated with either 9 mg of extended-release paliperidone ER or…
- Trial name
- NCT00105326
- Testing
- paliperidone ER
- Volunteers
- 5 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Sleep Apnea, Continuous Positive Airway Pressure
Circadian Variations of Prostaglandin in Sleep Apnea
The purpose of this study is to evaluate the associations of circadian variations, sleep architecture, hypertension and prostanoids in the patients with sleep apnea.
- Conditions
- Sleep Apnea, Continuous Positive Airway Pressure, Prostaglandins, Circadian Variations
- Trial name
- NCT01096433
- Testing
- CPAP treatment
- Where
- Japan
- Volunteers
- 64 people
- Sponsor
- Kyoto University
Sleep, Sleep Deprivation
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
This study aims to investigate the effect of a 15-minute meditation practice on sleep architecture and high-frequency Heart Rate Variability (HF-HRV), as well as cognitive performance after both a well-rested and sleep-deprived…
- Conditions
- Sleep, Sleep Deprivation, Cognitive Change
- Trial name
- REST (NCT05026541)
- Testing
- Nap Practitioners, Shoonya Meditation
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy, Sleep Quality
Study to Investigate Effects of a Herbal Drug Compared to Placebo on Sleep
To demonstrate the influence of a herbal preparation containing hypericum, passionflower, and valerian on sleep structure, improvement of attention, and well-being in comparison to placebo.
- Trial name
- sleep-EEG (NCT00997256)
- Testing
- Neurapas® balance (Herbal product (Hypericum, Passionflower, Valerian)), film-coated sugar-pill
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Sleep-Disordered Breathing, Sleep Architecture
Belun Ring Platform With an Improved Algorithm for OSA Assessment
OSA is commonly diagnosed with either attended in-lab polysomnography (PSG) or unattended home sleep apnea testing (HSAT). The BLS-100 (Belun Technology Company Limited, Hong Kong) is a novel neural network-based HSAT platform…
- Trial name
- NCT04885062
- Testing
- Belun Ring, PSG
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Belun Technology Company Limited
HIV (Human Immunodeficiency Virus), Sleep
Sleep Outcomes and Multidimensional Sleep Assessment - a Randomized Trial of Dolutegravir- vs Doravirine-based Antiretroviral Therapy in People Living With HIV
In South Africa, antiretroviral therapy (ART) has transformed HIV into a chronic, manageable condition, with high rates of viral suppression.
- Trial name
- SOMNART (NCT07673965)
- Testing
- Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Doravirine 100mg, Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Dolutegravir 50mg
- Volunteers
- 40 people
- Sponsor
- University of Witwatersrand, South Africa
Sleep-Disordered Breathing, Sleep Architecture
Ring-type Pulse Oximeter for Evaluation for Sleep Assessment Study
Recently, various electronic lifestyle activity monitoring devices (ELAM) are increasingly commercially available. However, the quality and reliability of the data from ELAM are unclear, compared with polysomnography (PSG), which…
- Trial name
- ROSA (NCT06221124)
- Testing
- Belun Ring Pulse Oximeter
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Belun Technology Company Limited
Fatigue, Sleep
Sleep Architecture and Chemotherapy-Related Fatigue
The purpose of this study is to identify specific chemotherapy-related changes in sleep stages/architecture that may relate to an increase in fatigue in individuals with cancer.
- Conditions
- Fatigue, Sleep, Cancer
- Trial name
- NCT00178204
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Rochester
Insomnia, Chronic Insomnia
Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder
Chronic insomnia disorder is a common condition in which people have ongoing difficulty falling asleep, staying asleep, or waking too early.
- Conditions
- Insomnia, Chronic Insomnia, Chronic Insomnia Disorder, Sleep Disturbance
- Trial name
- NCT07595185
- Testing
- TMS
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- San Francisco Neurology and Sleep Center