Clinical trials: Sleep Apnea
Sleep Apnea, End Stage Renal Disease
Impact of Different Dialysis on Sleep Apnea in Patients With Renal Failure
The purpose of this study is to determine whether hemodiafiltration, a new form of hemodialysis can improve sleep apnea in patients with end stage kidney disease.
- Trial name
- NCT00380848
- Testing
- Hemodiafiltration
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sleep Apnea, Obesity
Sleep Apnea-Hypopnea Syndrome and the Pathogenesis of Obesity
The hypothesis of the study is the following: Patients with sleep apnea-hypopnea syndrome have different pattern in the secretion of hormones.
- Trial name
- NCT00456651
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea, Hypertension
Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime Sleepiness
The objective of the study is to evaluate the effect of CPAP over the incidence of cardiovascular events and diagnosis of arterial hypertension in patients with sleep apnea.
- Conditions
- Sleep Apnea, Hypertension, Cardiovascular Diseases
- Trial name
- NCT00127348
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea, Cardiovascular Diseases
Platelet Activation and Circadian Rhythms of Clotting-Fibrinolysis Factors in Patients With Sleep Apnea Syndrome
The objective of the study is to define and compare clotting- fibrinolysis patterns, platelet function markers and endothelial dysfunction in patients with SAHS before and after treatment and normal controls age and weight…
- Trial name
- NCT00456287
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea Syndrome, Nonalcoholic Steatohepatitis
Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis
This study aims to evaluate the impact of nasal continuous positive airway pressure (nCPAP) treatment on liver enzymes in patients with sleep apnea syndrome and nonalcoholic steatohepatitis.
- Trial name
- NCT00152711
- Testing
- nCPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Heart Failure
Cardiac Function After CPAP Therapy in Patients With Chronic Heart Failure and Sleep Apnea. A Multicenter Study
The role of continuous positive airway pressure (CPAP) in cardiac function in patients with CSA and OSA has been studied with varying results.
- Conditions
- Sleep Apnea, Heart Failure, Cardiovascular Diseases
- Trial name
- NCT00404807
- Testing
- CPAP(Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Apnea, Snoring
Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS)
The aim of this prospective study is to evaluate the results of polidocanol sclerotherapy of pharynx for OSAS \& SS,to reduce pharyngeal compliance.
- Trial name
- NCT00399451
- Testing
- Polidocanol Sclerotherapy
- Volunteers
- 30 people
- Sponsor
- Liaoyang Central Hospital
Obstructive Sleep Apnea, Atherosclerosis
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment
Obstructive sleep apnea (OSA) is associated with adverse cardiovascular outcomes, including acute myocardial infarction and stroke. Atherosclerosis is an important step for these events.
- Trial name
- NCT00400543
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Sleep Apnea
Polymorphisms in Inflammatory Cytokines Genes in Subjects With Obstructive Sleep Apnea
Obstructive sleep apnea is a common sleep disorder. It is known to be related with increased body mass, abdominal obesity, insulin resistance and hypertension. It is currently believed to be a feature of the metabolic syndrome.
- Trial name
- NCT00395590
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Sleep Apnea Syndromes, Sleep Apnea
Mandibular Advancement Device for Obstructive Sleep Apnea
The purpose of this study was to determine how effective a custom-made standard dental splint (activator) advancing the lower jaw forward is in treatment of obstructive sleep apnea, and further to find factors for identification…
- Conditions
- Sleep Apnea Syndromes, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- NCT00243139
- Testing
- Mandibular advancement device (activator)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Nykøbing Falster County Hospital
Obstructive Sleep Apnoea Hypopnoea Syndrome
REMStar Auto With C-Flex - In-Laboratory Performance v. Conventionally Titrated CPAP Therapy: Performances and Preferences
This study will evaluate the use of REMStar Auto with C-Flex (RSA C-Flex) therapy in subjects with previously diagnosed obstructive sleep apnea / hypopnea syndrome, during in-laboratory studies.
- Trial name
- NCT00358800
- Testing
- REMStar Auto with C-Flex
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Sleep Apnea Syndrome
Cough Reflex and Obstructive Sleep Apnea Syndrome
Up to 70% of obese patients undergoing bariatric surgery have obstructive sleep apnea syndrome (OSAS). OSAS is responsible for laryngeal sensory impairment.
- Trial name
- NCT00317083
- Testing
- Cough reflex test
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Bichat Hospital
Obstructive Sleep Apnea
Comparison Between Auto CPAP and Fixed CPAP in Chinese Patients With OSA
AutoCPAP would lead to better compliance than FixCPAP
- Trial name
- NCT00307424
- Testing
- AutoCPAP, FixCPAP
- Where
- 2 sites in China
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea, Snoring
The Role of Clinical Parameters in Predicting the Severity of Obstructive Sleep Apnea
Investigate the role of clinical parameters in predicting the severity of obstructive sleep apnea
- Trial name
- NCT00302614
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea Syndrome
Improvement in Baroreflex Sensitivity in OSAS
Individuals with obstructive sleep apnea syndrome (OSAS) are at high risk for cardiovascular morbidity and mortality. The effect of long-term nocturnal therapy with continuous positive airway pressure (CPAP) on daytime baroreflex…
- Trial name
- NCT00284037
- Testing
- continuous positive airway pressure therapy
- Where
- Japan
- Sponsor
- Nagoya University
Sleep Apnea, Hypertension
Spanish Cohort for the Study of the Effect of CPAP in Hypertension (CEPECTA)
AIMS:To know the effects of the treatment with nasal positive continuous airway pressure (CPAP) on systemic blood pressure and the expression of biological mediators, in systemic hypertension of recent diagnostic, whose have an…
- Trial name
- NCT00202527
- Testing
- Nasal continuos positive airway pressure
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea
A Randomized Study to Compare Polysomnography With Overnight Home Oximetry and Auto - CPAP for Sleep Apnea
This study will look at an alternative new pathway for diagnosis and treatment based on simple procedures in the patient's own home compared with the current conventional laboratory based pathway.
- Trial name
- NCT00254059
- Testing
- Ambulatory diagnosis and titration with nasal CPAP using over night oxymetry and auto CPAP and vs conventional diagnosis and titration using polysomnography
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Sleep Apnea Syndrome
Treatment of Sleep Apnea Syndrome With nCPAP Versus Oral Appliance
This prospective randomized cross over study aims to compare nCPAP with mandibular advancement device for the treatment of sleep apnea syndrome.The effectiveness of nCPAP and oral appliance on apnea-hypopnea index, daytime…
- Trial name
- NCT00152672
- Testing
- nCPAP vs oral appliance
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Snoring, Sleep Apnea Syndromes
Clinical Study to Determine Safety and Effectiveness of KEEPASLEEP Device in Simple Snorers.
Study to demonstrate the safety and effectiveness of a new oral enhanced airway device to treat simple snoring.
- Trial name
- NCT00211627
- Testing
- KEEPASLEEP enhanced breathing device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Miller, Chipp St. Kevin, M.D.
Sleep-Disordered Breathing
Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing
The diagnosis and treatment of sleep disordered breathing have come to the forefront of clinical medicine following recognition of the high prevalence and associated morbidity of sleep apnea.
- Trial name
- NCT00004569
- Testing
- Non-invasive technique to diagnose and quantitate sleep-disordered breathing
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)