Clinical trials: Sleep Apnea
Pregnancy Related, Sleep-Disordered Breathing
Sleep Disordered Breathing, Endothelial Function, and Adverse Events in Pregnancy
This is a prospective longitudinal cohort study whereby pregnant individuals are asked to complete an 8-day testing protocol to measure their sleep and cardiovascular health at two timepoints during pregnancy.
- Trial name
- SLEEP (NCT05908591)
- Where
- Canada
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea (OSA)
Level 3 Validation Study
This study will compare the output of a new Level 3 polysomnography system against in-laboratory polysomnography.
- Trial name
- NCT07688603
- Testing
- Comparison 1: Level 1 Polysomnography: Cadwell/Alice, Comparison 2: Level 3 Test: Berry Sleep Apnea Screening Monitor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Windsor Sleep Disorders Clinic
Sleep Apnea, Spinal Cord Injury
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
This study will investigate potential therapeutic approaches for sleep-disordered breathing (SDB) in patients with chronic cervical spine injury (>6 months post-injury).
- Trial name
- NCT02922894
- Testing
- Acute episodic hypoxia, Supplemental oxygen, Trazodone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- John D. Dingell VA Medical Center
Sleep Apnea, Opioid Use
Sleep Disordered Breathing With Opioid Use
There is an increased risk for sleep disordered breathing (SDB), sleep-related hypoventilation and irregular breathing in individuals on chronic prescription opioid medications.
- Conditions
- Sleep Apnea, Opioid Use, Sleep Disordered Breathing
- Trial name
- SDB (NCT05589753)
- Testing
- Hyperoxia, Acetazolamide
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Atrial Fibrillation, Obstructive Sleep Apnea
Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study
The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic…
- Trial name
- NCT04814420
- Testing
- Delayed enhancement magnetic resonance imaging (DE-MRI)
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tulane University
Sleep-Disordered Breathing
HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men
Randomized clinical trial evaluating the effect of acetazolamide on sleep disordered breathing in women compared to men travelling to 3600 m.
- Trial name
- NCT06498531
- Testing
- Acetazolamide
- Where
- Kyrgyzstan
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sleep-Disordered Breathing
HighCycle Study: Effect of High Altitude on Sleep Disordered Breathing in Women Related to Their Menstrual Cycle Phase
Prospective cohort study investigating the menstrual cycle phase (MCP) dependent sleep disordered breathing (SDB) in women travelling to 3600 m.
- Trial name
- NCT06498544
- Testing
- Exposure to 3600 m
- Where
- Kyrgyzstan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea
Effect of Longitudinal Sleep Monitoring on Diagnosis and Treatment Decision in Patients With Suspected Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing disease, caused by recurrent episodes of partial or complete collapse of the upper airway during sleep, resulting in intermittent hypoxia, fragmented…
- Trial name
- ELSA (NCT03819361)
- Testing
- pulse-oximetry
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Malcolm Kohler
Obstructive Sleep Apnea
Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical condition where a person has great difficulty with breathing, or stops breathing all together, while asleep.
- Trial name
- NCT06960200
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea, Insomnia
Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA
The comorbidity between obstructive sleep apnea (OSA) and insomnia (COMISA) is common, and associated with poorer sleep quality. CPAP adherence among COMISA patients is worst than among those with OSA only.
- Trial name
- NCT06017921
- Testing
- Eszopiclone 3 mg
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Apnea, Obstructive Sleep, Obstructive Sleep Apnea
OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA).
- Trial name
- OSA-18 (NCT05911646)
- Testing
- OSA-18 Survey, Decisional Conflict (DCS)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Sleep Apnea, Obstructive
Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea
The purpose of this study is to evaluate the sensitivity and specificity of the Belun Ring Pulse Oximetry system for screening of obstructive sleep apnea (OSA) in adults during standard polysomnography sleep study conditions.
- Trial name
- NCT04121923
- Testing
- Belun Ring Pulse Oximeter
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Belun Technology Company Limited
Dysphagia, OSA
Obstructive Sleep Apnea (OSA), Oral Frailty, Dysphagia, Continuous Positive Airway Pressure (CPAP)
The purpose of this study is to evaluate the effects of the CPAP treatment on oral frailty and dysphagia among OSA patients.
- Conditions
- Dysphagia, OSA, CPAP
- Trial name
- NCT05977296
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Pediatric Obstructive Sleep Apnea
Pediatric Obstructive Sleep Apnea Among Dental Interns in Egyptian Universities
Pediatric obstructive sleep apnea (OSA) is a common yet underdiagnosed sleep-related breathing disorder in children that may result in serious health and behavioral complications if left untreated.
- Trial name
- NCT07604831
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstructive Sleep Apnea (OSA)
Data Collection Study to Review Novel Methods for Diagnosing Obstructive Sleep Apnea
This study will collect data on a range of signals such as facial scans, videos (including speaking, blinking and swallowing) and heart rate variability to assess whether any of these measures are useful for diagnosing…
- Trial name
- Ignite (NCT06930404)
- Testing
- facial scans, videos and heart rate variability measurements
- Where
- Australia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- ResMed
Sleep Related Breathing Disorder, Snoring
IOA Preventing Occlusal Changes With MAD Use
This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive…
- Conditions
- Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite
- Trial name
- NCT07103941
- Testing
- AM Aligner, Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Isabel Moreno Hay
Obstructive Sleep Apnea, Postoperative Pain
Effect of Sleep Apnea on Pain After Dental Treatment
This observational study aims to investigate the effects of sleep quality and systemic health status on pain levels following endodontic treatment in adult patients.
- Conditions
- Obstructive Sleep Apnea, Postoperative Pain, Hypertension Complicated With Type 2 Diabetes
- Trial name
- OSA-EndoPain (NCT07581964)
- Testing
- Standard Endodontic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Harran University
Sleep Apnea, Glucose Metabolism Disorders
Obstructive Sleep Apnea and Glucose Metabolism
Many adults who are overweight have obstructive sleep apnea (OSA) which disrupts sleep and makes it difficult to breath during the night. OSA increases the risk for a person to become insulin resistant and diabetic.
- Trial name
- OSAGM (NCT03408613)
- Testing
- Positive Airway Pressure, Supplemental Oxygen
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obstructive Sleep Apnea
Exploring the Use of Phototherapy to Improve CPAP Compliance
Photobiomodulation (PBM) is a type of light therapy like lasers and LEDs. PBM was previously known by different terms like "low-level laser therapy" (LLLT) or "photobiostimulation." LLLT, despite its name, can also have effects…
- Trial name
- NCT06960161
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Sleep Apnea Syndromes
Effect of Compression Stockings on the Number of Apneas/Hypopneas Per Hour of Sleep in Patients With Syndrome Obstructive Sleep Apnea/Hypopnea as Compared to no Treatment
The sleep apnea-hypopnea syndrome is characterized by the occurrence, during sleep, of abnormally frequent episodes of interruption of ventilation (apnea), or significant reduction in ventilation (hypopnea).
- Trial name
- NCT05477719
- Testing
- Wearing of specific compression stockings
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sigvaris France