Clinical trials: Skin Sores
Varicose Ulcer, Varicose Veins of Lower Limb
Venous Ulcer: Endovenous Radiofrequency Treatment Trial
The aim of this study is to analyze the effect of intravenous therapy with radiofrequency for superficial and perforating venous insufficiency versus compression therapy with multilayer banding in patients with active venous…
- Conditions
- Varicose Ulcer, Varicose Veins of Lower Limb, Saphenous Vein Injury
- Trial name
- VUERT (NCT03293836)
- Testing
- Radiofrequency ablation, Multilayer Compressive Bandage
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Juliana Puggina
Diabetic Foot, Neuropathic Foot Ulcer
Application of S26E for Diabetic Foot Ulcer Healing
A randomized, controlled open-label, parallel group study to examine the effectiveness of a local application of the kalahari melon (Citrullus lanatus) seed oil for the healing of non-infected diabetic foot ulcers.
- Conditions
- Diabetic Foot, Neuropathic Foot Ulcer, Chronic Diabetic Ulcer of Left Foot (Diagnosis), Chronic Diabetic Foot Ulcer of Right Foot
- Trial name
- NCT04186377
- Testing
- Standard-of-care for neuropathic/neuroischemic diabetic foot ulcers, S26E
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- National and Kapodistrian University of Athens
Bed Sores
Evaluating the Impact of Vitamin D Supplementation on Healing Bed Sores in ICU.
To study the value of vitamin D supplementation on healing bed sores in ICU patients.
- Trial name
- NCT07813975
- Testing
- Enteral Vit-D 3 (cholecalciferol)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Maha Salah
Ulcer, Skin
Acetic Acid 2% Solution for Skin Ulcers
The objective of this clinical trial is to assess the effectiveness of acetic acid in patients suffering from chronic cutaneous ulcers with biofilm.
- Trial name
- ECA-AA (NCT06297967)
- Testing
- Acetic Acid, Prontosan
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Venous Ulcer
Immediate Versus Early Endovenous Ablation In Venous Ulcer
The study is conducted to assess the effects of immediately started foam sclerotherapy in venous ulcer compared to early intervention.
- Trial name
- NCT03795064
- Testing
- Foam sclerotherapy, Endothermal ablation
- Where
- Finland
- Volunteers
- 23 people
- Sponsor
- Oulu University Hospital
Diabetic Foot Ulcer
Diabetes Foot Care Clinical Pathway Project - Exciton Technologies Inc
In 2011, the premiers of all Canadian provinces and territories selected diabetes foot care as 1 of 3 significant targets for pan-provincial action.
- Trial name
- DFCCP-Exciton (NCT02990832)
- Testing
- Exciton
- Sponsor
- University of Alberta
Stasis Dermatitis
Study Evaluating Efficacy and Safety of Crisaborole in Adults With Stasis Dermatitis
This is a Phase 2a, randomized, double blind, vehicle controlled, parallel group, proof of concept study that will include participants with stasis dermatitis without active skin ulceration, who will receive crisaborole ointment…
- Trial name
- NCT04091087
- Testing
- crisaborole ointment, vehicle ointment
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Pfizer
Pyoderma Gangrenosum, Crohn's Disease
Open Label Study for Adults With Pyoderma Gangrenosum and Inflammatory Bowel Disease
Subjects must be 18- 75 years old and have a history of both inflammatory bowels disease (Crohn's or ulcerative colitis) and pyoderma gangrenosum. This is a 6 month open label study of an intravenous (IV) medication.
- Conditions
- Pyoderma Gangrenosum, Crohn's Disease, Ulcerative Colitis, Inflammatory Bowel Disease
- Trial name
- NCT00791557
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetic Foot Ulcer
Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With a Mild Infection of a Foot Ulcer
The purpose of this study is to determine whether the gentamicin-collagen sponge when combined with standard of daily wound care is safe and effective in treating mildly infected skin ulcers compared to treatment with an oral…
- Trial name
- NCT00593567
- Testing
- gentamicin-collagen sponge, Levofloxacin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Innocoll
Diabetic Foot Ulcer (DFU)
A Study to Evaluate Safety and Efficacy of APO-2 at Three Different Doses in Patients With Diabetic Foot Ulcer
The MARSYAS II study which will be conducted in patients with diabetic foot ulcer (DFU) consists of a Lead-In Phase for safety assessment of multiple doses of the biologic investigational medicinal product (IMP) APO-2 and of a…
- Trial name
- NCT04277598
- Testing
- APO-2
- Where
- 14 sites in Austria, Czechia and 2 more
- Volunteers
- 159 people
- Sponsor
- Aposcience AG
Chronic Foot Ulcers
DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes
A randomized versus placebo trial designed to evaluate the clinical and humoral effects of 4 months of vildagliptin on healing of chronic ulcers in type 2 diabetes.
- Trial name
- NCT01472432
- Testing
- vildagliptin
- Where
- Italy
- Volunteers
- 106 people
- Sponsor
- University of Campania Luigi Vanvitelli
Diabetic Foot Ulcer
Evaluation of Combinational Use of Negative Pressure Wound Therapy (NPWT) for Diabetic Foot Wounds
Singapore has one of the world's highest diabetes-related lower limb amputation rates in the world. Between 2008 - 2017, 4724/5306 (89.0%) of all major amputations and 6656/7227 (92.1%) of all toe/ray amputations performed in…
- Trial name
- NCT06832787
- Testing
- Negative Pressure Wound Therapy, Kerecis, Delayed primary closure with local flap
- Where
- 2 sites in Singapore
- Volunteers
- 75 people
- Sponsor
- Singapore General Hospital
Diabetic Foot Ulcers
Clinical and Cost Effectiveness of Different Dressing Materials in Diabetic Foot Ulcers
The purpose of the study is to evaluate the efficacy and safety of different commonly used dressings for treating diabetic foot ulcers.
- Trial name
- NCT01105884
- Testing
- Normal Saline, Biatin Ag (Foam), Hydrocolloid
- Where
- India
- Sponsor
- M.V. Hospital for Diabetes
Wound Healing
Efficacy Study of a Bioelectric Dressing Used With Negative Pressure Wound Therapy to Treat Diabetic and Pressure Ulcers
The purpose of this study is to determine whether a bioelectric wound dressing, used in conjunction with Negative Pressure Wound Therapy (NPWT), is effective in the treatment of diabetic and pressure ulcers of the foot.
- Trial name
- NCT01022216
- Testing
- Procellera™ Wound Dressing with V.A.C.® Therapy, V.A.C.® Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vomaris Innovations
Foot Ulcers, Diabetic, Foot Ulcer Unhealed
SALACIA: SALvesAn vs Conventional Management of dIAbetic Foot Wounds
Increasing prevalence of diabetes mellitus has led to increasing numbers of chronic non-healing foot ulcers (wounds). Electrolysed water is a novel antiseptic which reduces bacterial load and appears to encourage wound healing.
- Trial name
- SALACIA (NCT06908148)
- Testing
- Electrolysed water, Conventional irrigant
- Volunteers
- 200 people
- Sponsor
- NHS Lanarkshire
Diabetic Foot, Diabetic Foot Ulcer
Shear Load In-shoe Plantar Sensing/Strain Analyses and Mapping in Diabetic Foot Ulcers
Stain Analysis Mapping of the Plantar surface (STAMP) is a method designed by the University of Leeds to measure 'in-shoe' strain patterns on the plantar surface of the foot.
- Trial name
- SLIPSTREAM (NCT05687643)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Healthy
Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)
The purpose of the study is to determine the relative pharmacodynamic effects and safety of crushed and whole ALO-01 compared to MSIR and to Placebo, and of crushed ALO-01 to whole ALO-01; to determine the relative…
- Trial name
- NCT00751478
- Testing
- ALO-01, MSIR
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pfizer
Decubitus Ulcer
Investigation of the Effect of Blood Pressure on Bedsores
The aim of this study is to comprehensively investigate the effect of blood pressure levels on the development of bedsores (pressure ulcers) in adult patients hospitalized in the internal medicine intensive care unit.
- Trial name
- NCT07696416
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Yuzuncu Yil University
Skin Cancer, Skin Diseases
Multi-modal Quantitative Imaging of the Skin
This clinical trial is about evaluating the suitability of multi-modal imaging technology, which covers virtually the entire body, to evaluate the possibility of screening and early detection of disease.
- Conditions
- Skin Cancer, Skin Diseases, Atopic Dermatitis, Psoriasis
- Trial name
- DermaFlow (NCT06989216)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Pressure Ulcer, Inflammatory Response
Combined Molecular and Mechanistic Methods for Detection of Pressure Ulcers
This project aims to develop a novel method for identifying early tissue damage related to pressure ulcer (PU) development in vulnerable patients by measuring biomarkers of inflammation on the skin surface.
- Trial name
- NCT06468306
- Testing
- non-invasive ventilation teraphy, NIV
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
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