Clinical trials: Skin Cancer Prevention
Prevention
Using Physical Tracking to Predict Sunburn
Recreational UV exposure is associated with every form of skin cancer and individuals who engage in more physical activity have a higher prevalence of sunburn, a proximal biomarker of melanoma risk, perhaps explaining why…
- Trial name
- NCT04977700
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Breast Cancer
A Study to Prevent Rash in People Starting Alpelisib for the Treatment of Breast Cancer
The researcher are doing this study to find out whether benralizumab is effective at preventing skin rashes caused by alpelisib in people who have metastatic breast cancer. Skin rash is a common side effect of alpelisib.
- Trial name
- NCT05966584
- Testing
- Benralizumab, fulvestrant or AIs) and PI3K inhibition (alpelisib)
- Where
- 7 sites in United States
- Volunteers
- 1 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Lymphedema, Shoulder Injury
Interhospital Variability in Programmes to Prevent Axillary Lymphadenectomy Sequels in Breast Cancer Patients.
This study aims to determine the effectiveness of the different programmes of four Spanish hospitals about prevention of axillary lymphadenectomy sequels in breast cancer patients.
- Trial name
- NCT03300349
- Testing
- Fulfillment of a preventive programme, No fulfillment of a preventive programme
- Where
- 5 sites in Spain
- Volunteers
- 276 people
- Sponsor
- Violeta Pajero Otero
Breast Cancer Screening, Cervical Cancer Screening
Cancer Awareness Among Syrian Migrants
This study aims to develop and evaluate a theory-based educational intervention to improve cancer screening participation among Syrian migrants in Turkey.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colorectal Cancer Screening, Cancer Prevention Behavior
- Trial name
- NCT07541105
- Testing
- PMT-Based Cancer Screening Educational Intervention, PMT-Based Cancer Screening Education Program
- Volunteers
- 30 people
- Sponsor
- Toros University
Breast Neoplasms, Osteoporosis
Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy
This protocol is designed to compare the effect on bone of Zoledronic Acid 4 mg every 6 months when given upfront versus delayed start (based on a post-baseline BMD T- Score below -2.0 SD at either the lumbar spine or total hip…
- Trial name
- NCT00050011
- Testing
- Zoledronic Acid, Letrozole
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 602 people
- Sponsor
- Novartis Pharmaceuticals
Cancer
Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related Infection
RATIONALE: Heparin or M-EDTA may prevent catheter-related infections and blockages in patients at high risk for a catheter-related infection.
- Trial name
- NCT00378781
- Testing
- Heparin, Minocycline-EDTA
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Randomized Study Versus Placebo for the Prevention of Neurotoxicity Induced by Weekly PACLITAXEL
This study recommends the use of OnLife dietary supplement, which will be followed by a few day before the initiation of PACLITAXEL, for the prevention of PACLITAXEL induced neuropathy.
- Trial name
- NEUROTAX (NCT05695313)
- Testing
- OnLife®
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Georges Francois Leclerc
Skin Cancer
Using Technology to Scale-Up an Occupational Sun Protection Policy Program
Comprehensive approaches that combine sun protection policy and education for outdoor workers can reduce their risk for skin cancer by reducing their exposure to solar ultraviolet radiation on the job.
- Trial name
- SSW-T (NCT03278340)
- Testing
- Sun Safe Workplaces - Technology, Sun Safe Workplaces -In Person
- Where
- 2 sites in United States
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Breast Cancer
Automated Tele Counseling for Screening Mammography
The purpose and aim of this study is to test the use of a computer-based, automated telecommunications system and its effectiveness in increasing the rates of regular screening mammography among women ages 50-74.
- Trial name
- NCT00247013
- Testing
- Breast Cancer Screening Compliance
- Where
- United States
- Volunteers
- 2,120 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Atypical Ductal Breast Hyperplasia, BRCA1 Gene Mutation
Pilot Study of Curcumin for Women With Obesity and High Risk for Breast Cancer
This randomized pilot clinical trial studies a nanoemulsion formulation of curcumin in reducing inflammatory changes in breast tissue in obese women at high risk for breast cancer.
- Conditions
- Atypical Ductal Breast Hyperplasia, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Ductal Breast Carcinoma in Situ
- Trial name
- NCT01975363
- Testing
- curcumin, Biomarker analysis, Assessment of Dietary Intake
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Neoplasm, Brain Neoplasm
Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2)
The purpose of this study is to determine whether temozolomide can be used as a prophylaxis against brain recurrence in participants with metastatic breast cancer.
- Conditions
- Breast Neoplasm, Brain Neoplasm, Second Neoplasm
- Trial name
- STOP (NCT00638963)
- Testing
- temozolomide
- Volunteers
- 6 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer, Heart Failure
Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy
Women treated for breast cancer are at increased risk for cardiovascular disease, including heart failure. In this study, by using magnetic resonance imaging (MRI), the investigators want to assess if heart failure medications…
- Trial name
- PRADA (NCT01434134)
- Testing
- Metoprolol, Candesartan
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- University Hospital, Akershus
Breast Cancer
Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients
Ionizing radiation is a toxic agent and widely accepted form of treatment for various types of cancer. Despite advances in medical technology, radiation therapy still causes severe early and late skin effects.
- Trial name
- NCT01042938
- Testing
- Curcumin C3 Complex
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Rochester
Breast Cancer
CBPR - BRCA Genetic Testing Among Orthodox Jews
This study evaluates a web-based decision aid, named RealRisks, in promoting genetic testing intention among Orthodox Jewish women.
- Trial name
- NCT03624088
- Testing
- RealRisks
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Cancer, Breast, Cancer, Colon
Enhancing Cancer Prevention and Control Pathways-Native Health Initiative
There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US.
- Conditions
- Cancer, Breast, Cancer, Colon, Cancer, Cervix
- Trial name
- NCT04259762
- Testing
- Aim 8 (INT, Pilot Test): Breast, Colorectal, and Cervical Cancer Screening Cognitive-Behavioral Interventions
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Breast Cancer
Gedatolisib, Hydroxychloroquine or the Combination for Prevention of Recurrent Breast Cancer ("GLACIER")
This clinical trial will assess the safety and early efficacy of the role of gedatolisib and hydroxychloroquine in early-stage breast cancer patients with residual disease and evidence of disseminated tumor cells (DTCs) on bone…
- Trial name
- GLACIER (NCT03400254)
- Testing
- Hydroxychloroquine (HCQ), Gedatolisib
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer, Lymphedema
Lymphedema Prevention in Breast Cancer
OBJECTIVE: To find out the effectiveness of early application of Manual Lymph Drainage in the prevention of upper limb lymphedema after breast surgery and axillary lymphadenectomy in women with breast cancer.
- Trial name
- NCT04112966
- Testing
- 14 sessions of manual lymphatic drainage technique, the health education
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Castilla-La Mancha
Breast Cancer
Increasing Screening for Cancer Using EHR-Nudges Replication
In this study, personalized nudges to clinicians and patients will be evaluated to help increase breast cancer screening rates in accordance with USPSTF guidelines among women with a primary care visit.
- Trial name
- I-SCREEN Rep (NCT06995703)
- Testing
- Pre-Visit Patient Text Message, Post-Visit Patient Text Messages, Smart Data Element (SDE)
- Where
- United States
- Volunteers
- 8,490 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Arthralgia, Breast Neoplasms
Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients With Stage I-III Breast Cancer
This clinical trial studies the use of omega-3 fatty acid supplementation in preventing aromatase inhibitor-induced toxicity in patients with stage I-III breast cancer.
- Trial name
- NCT02831582
- Testing
- Omega-3 Fatty Acid
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Nausea, Vomiting
An Investigational Drug for the Prevention of Chemotherapy-Induced Nausea and Vomiting (MK-0869-071)
This protocol will study an investigational drug treatment plan against standard therapy in the prevention of chemotherapy-induced nausea and vomiting in patients diagnosed with breast cancer who are to be treated with up to 4…
- Conditions
- Nausea, Vomiting, Breast Neoplasms
- Trial name
- NCT00092183
- Testing
- MK0869, aprepitant / Duration of Treatment: 3 days, Comparator: ondansetron / Duration of Treatment: 3 days
- Volunteers
- 866 people
- Sponsor
- Merck Sharp & Dohme LLC