Clinical trials: Skin Cancer
Skin Cancer
Multi-Center Study to Evaluate the Performance of DermDx for Primary Care Physicians in the Detection of Skin Cancers
The proposed study is a pivotal, multi-center retrospective reader study designed to determine whether the use of DermDx as a concurrent reading aid improves the performance of primary care physicians (PCPs) in diagnosing skin…
- Trial name
- NCT06463860
- Testing
- DermDx
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- MetaOptima Technology Inc.
Breast Cancer Female, Breast Cancer
Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
This is a prospective clinical trial that will examine if contrast-enhanced mammography substantially improves breast cancer detection compared to mammography with tomosynthesis, with minimal increase in false-positives, in women…
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms, Neoplasms
- Trial name
- TOCEM (NCT04085510)
- Testing
- Contrast-enhanced mammogram
- Where
- 3 sites in United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Breast Neoplasms, Quality of Life (QOL)
A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer Patients
This study, called PERSEVERE, examines how local treatment for early breast cancer affects people's health and daily lives over time.
- Conditions
- Breast Neoplasms, Quality of Life (QOL), Toxicities, Breast Diseases
- Trial name
- PERSEVERE (NCT07010939)
- Testing
- blood sampling
- Where
- 3 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- FangYi
Breast Cancer
Health SMART (Stress Management and Relaxation Training)
The study will examine the effects of a cognitive behavioral stress management (CBSM) group intervention on antibody and cellular immune function among women who are at elevated risk for breast cancer because of family history.
- Trial name
- NCT01048528
- Testing
- Cognitive Behavioral Stress Management (CBSM)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Breast Cancer
Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer.
- Trial name
- NCT00900367
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, spectroscopy
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neoplasia
The Suitability of Sniff Dog as a Tool in Screening Tumors
Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces.
- Trial name
- NCT02049645
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Chang-Qing Gao
Anogenital Warts, HIV
The Role of Genital Warts in HIV Acquisition in Peru
The primary objective of this study is to determine the role of genital warts (GW) on Human Immunodeficiency Virus (HIV) acquisition among men who have sex with men (MSM) in Peru.
- Trial name
- VIVA (NCT01387412)
- Where
- Peru
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Breast Cancer
A Evaluation of 3D Functional MIRA System in Women With Mammographically Dense Breasts
The purpose of this image acquisition study is to compare, in a Reader Study, the RI8 system used in conjunction with a conventional mammography to mammography alone, and to determine whether the addition of supplementary RI8…
- Trial name
- NCT03288792
- Testing
- RI8 device imaging
- Where
- 5 sites in United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Cancer
HGWD Improve the Paclitaxel-related Neurotoxicity in Patients With BC
The current treatments for albumin-bound paclitaxel (nab-PTX) -related peripheral neurotoxicity (PN) mainly included cryotherapy and compression therapy , oral B group vitamin , and duloxetine.
- Trial name
- NCT05566457
- Testing
- Huangqi Guizhi Wuwu decoction (HGWD) infusion packs
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Arterial Thromboembolism, Venous Thromboembolism
Long-term Active Surveillance Study for Oral Contraceptives (LASS)
The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.
- Conditions
- Arterial Thromboembolism, Venous Thromboembolism, Breast Cancer
- Trial name
- NCT00676065
- Where
- Germany
- Volunteers
- 58,303 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Healthy Tissue, Muscles
Deep Optical Imaging of Tissue (DOIT)
In medical imaging, X-ray-based methods are widely used, which means that patients are exposed to ionizing radiation. In addition, invasive tissue samples often need to be taken with biopsy needles to, for example, safely…
- Conditions
- Healthy Tissue, Muscles, Extremity, Breast
- Trial name
- DOIT (NCT07754500)
- Testing
- Mk1
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Colorectal Neoplasms, Breast Neoplasms
Increasing Breast and Colorectal Cancer Screening in the Community
The goal of the proposed study is to conduct a pilot randomized controlled trial (RCT) of Chi gung, a community-based intervention using peer education and tailored navigation to simultaneously improve colorectal (CRC) and breast…
- Trial name
- NCT07748377
- Testing
- Chi gung: Stay Well, Live Well
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Breast Cancer
Blood Glycan Biomarkers in Women With Stage IV Breast Cancer
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur and identify biomarkers related to cancer.
- Trial name
- NCT00897962
- Testing
- Healthy Controls, Metastatic Breast Cancer, Non-cancer medical illness
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Oral Lichen Planus, Oral Squamous Cell Carcinoma
Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity
The aim of this study was to examine molecular alterations on the protein level in lesions of oral lichen planus (OLP), oral squamous cell carcinoma (OSCC) and healthy mucosa.
- Trial name
- NCT03026361
- Testing
- global proteomic profiling
- Where
- Croatia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Breast Cancer Stage IV
Study of Dotatate Imaging in Breast Cancer
This will be a Phase 2 clinical trial to assess somatostatin receptor (SSTR) expression in Stage IV estrogen receptor positive (ER+) breast cancer using Gallium-68 DOTATATE or Copper-64 DOTATATE PET/CT.
- Trial name
- NCT05880394
- Testing
- Gallium-68 DOTATATE, Copper-64 DOTATATE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hoag Memorial Hospital Presbyterian
Breast Cancer
Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples
Breast cancer is the most common cancer and cause of cancer- related deaths among women, accounting for 1.67 million (25.2%) new cases and 521,907 (14.7%) deaths worldwide.
- Trial name
- NCT05570266
- Testing
- Breast Cancer Risk Prediction Software
- Where
- Indonesia
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Nalagenetics Pte Ltd
Hereditary Breast and Ovarian Cancer Syndrome
Statewide Communication to Reach Diverse Low Income Women
Recruitment for prevention, and early detection among health disparities populations represents a major challenge in chronic disease control.
- Trial name
- NCT02956681
- Testing
- Intervention Group, Delayed Intervention Group
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Huntington Disease, Hereditary Breast and Ovarian Cancer
Genetic Risk: Whether, When, and How to Tell Adolescents
This study is being conducted to learn more about family communication of genetic risk information. Semi-structured interviews lasting up to one hour will be conducted with three populations: parent/child pairs at risk for…
- Conditions
- Huntington Disease, Hereditary Breast and Ovarian Cancer, Hereditary Cancer, Hereditary Non-polyposis Colon Cancer
- Trial name
- NCT03421327
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Melanoma (Skin), Carcinoma
App Teaches Doctors to Diagnose Skin Cancer
This study aimed to examine if self-paced learning with a novel digital patient-case-based educational platform can increase primary care physicians' diagnostic accuracy of malignant and benign skin lesions on both the level of…
- Trial name
- NCT05661370
- Testing
- Dermloop Learn
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
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