Clinical trials: Skeletal Muscle Performance
NSCLC Stage IV
Cachexia in NSCLC Patients: Diagnosis, Characterization, Prognosis, Functional and Skeletal Muscle Implications
LUCAX01 is a cohort study with patients with advanced NSCLC in tobacco users. in this study, patients will be submitted to baseline physical tests, blood and biopsy sample collection, and the main objective is to study the…
- Trial name
- LUCAX01 (NCT03960034)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Metabolic Stress
Analysis of Bioenergetics and Fatigue Responses in Basketball (TEAM)
The aims of the study are: 1. To examine skeletal muscle and blood metabolites during an official basketball game and to relate those to skeletal muscle performance during and after the game. 2.
- Trial name
- TEAM (NCT07250555)
- Testing
- BASKETBALL GAME
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Aging, Obesity
Resistance Exercise Training in the Older Population With Obesity
Background: Aging leads to an alteration in the immune response, characterized by a chronic inflammatory state, and a progressive decrease in muscle quantity and quality, a situation that increases in women and in the presence of…
- Trial name
- RETOPO (NCT06367296)
- Testing
- Prolonged resistance exercise training
- Where
- 2 sites in Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Heat-suit Endurance Training, Non-heat-suit Endurance Training
Effects of Heat-suit Training on Biological and Performance Characteristics in Elite Cyclists
The overall objective of the study is to investigate the effects of five weeks of heat-suit training on training-associated changes in hemoglobin mass, skeletal muscle characteristics and endurance exercise performance in elite…
- Trial name
- HeatME (NCT04611646)
- Testing
- Heat-suit endurance training, Non-heat-suit endurance training
- Where
- Norway
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Healthy
Effects of Mitopure (Urolithin A) on Skeletal Muscle Function, Iron Metabolism and Endurance Performance
This is a randomized, double-blind, placebo-controlled study enrolling 36 (16 Elite and 20 Sub-Elite trained endurance runners (18 placebo and 18 Mitopure intervention) who are 18-40 years of age.
- Trial name
- ENDURO (NCT04783207)
- Testing
- Mitopure
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Aging
Effect of Two Years of Resistance Training on Health Status in Postmenopausal Women: Longitudinal Study Active Aging.
Aging is a natural process of the life cycle that can result in morphological, neuromuscular, metabolic, physiological, cognitive and behavioral changes that can compromise quality of life, autonomy, self-esteem, health and life…
- Trial name
- NCT06621368
- Testing
- Exercise, Control-no treatment
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Aloe Vera Ointment Application and Skeletal Muscle Recovery
Aloe vera, sometimes described as pharmaceutical aloe, is a flowering succulent plant with many therapeutic properties such as wound and burn wound healing, treatment of diabetes and reduction of blood lipid profile.
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Performance
- Trial name
- NCT03934762
- Testing
- Natural Aloe Vera, Aloe vera soup
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Stroke, Inflammation
Inflammatory Abnormalities in Muscle After Stroke: Effects of Exercise
The purpose of this study is to first define whether abnormalities of skeletal muscle are related to the presence of inflammation and to poor motor performance and whether this can be modified by exercise interventions.
- Trial name
- NCT00387712
- Testing
- Velocity based treadmill training, Duration based treadmill training
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- VA Office of Research and Development
Aging
Plant-based Diet in Older People: What Consequences for Muscle Health?
This randomized, controlled, two-arm clinical study aims to determine how increasing the proportion of plant-based foods in the diet affects skeletal muscle strength, mass and function, protein metabolism, microbiota and key…
- Trial name
- MYOVEG (NCT07681986)
- Testing
- Plant-enriched dietary intervention, Control diet
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Skeletal Muscle Performance, Gene Polymorphisms
Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance
Study aims to verify the hypothesis: N-acetylcysteine (NAC) supplementation improves exercise capacity in people training endurance sports and the effectiveness of this supplementation depends on the polymorphism of genes related…
- Trial name
- NCT05604586
- Testing
- N-acetylcysteine
- Where
- Poland
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Healthy
Salmeterol Effect on Exercise Performance
The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.
- Trial name
- NCT06655012
- Testing
- Salmeterol
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hydroxymethylglutaryl-CoA Reductase Inhibitors, Muscular Diseases
The Effect of Statin Medications on Muscle Performance (The STOMP Study)
Statins are a group of medications that are used to lower cholesterol levels. Although serious side effects are rare, some people taking statins experience muscle pain or weakness.
- Trial name
- STOMP (NCT00609063)
- Testing
- Atorvastatin
- Where
- 3 sites in United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Upper Limb Spasticity (Altered Skeletal Muscle Performance) in Children
Efficacy And Safety Of Dysport In The Treatment Of Upper Limb Spasticity In Children
The purpose of this study is to assess the efficacy and safety of multiple doses of Dysport used in the treatment of upper limb spasticity (altered skeletal muscle performance) in children with cerebral palsy (CP).
- Trial name
- PUL (NCT02106351)
- Testing
- Botulinum toxin type A
- Where
- 31 sites in United States, Belgium and 6 more
- Volunteers
- 212 people
- Sponsor
- Ipsen
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players
Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance muscle recovery, demonstrating positive results.
- Trial name
- NCT03803956
- Testing
- Active PBMT
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Healthy, Cyclists
Effects of Including Sprints During Low-intensity Cycling Exercises on Performance and Muscle/Blood Characteristics
To investigate the effects of Including 30-s sprints during low-intensity cycling exercises during a training camp on performance and muscle/blood characterisitcs in elite cyclists
- Trial name
- NCT04640883
- Testing
- Inclusion of sprints during low-intensity cycling during a 14-day training camp (high training load), Low-intensity cycling during a 14-day training camp (high training load), Recovery for 10 days (low training load)
- Where
- Norway
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Cancer Cachexia, Omega 3
Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients
Cancer cachexia is a common and prognostically relevant complication of advanced malignancies, characterized by systemic inflammation, increased catabolism, and reduced nutritional intake, leading to a progressive loss of…
- Conditions
- Cancer Cachexia, Omega 3, Resistance Training, Cancer
- Trial name
- SUPPORT (NCT07643558)
- Testing
- Omega 3 FA (Fish Oil), Training
- Where
- Germany
- Volunteers
- 288 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertrophy, Physiologic Hypertrophy
Beta2-adrenergic Agonism and Muscle Remodelling
The study aims to investigate gender-specific adaptations to beta2-adrenoceptor stimulation with selective short- and long-acting beta2-agonist with emphasis on skeletal muscle in relation to performance enhancing effects and…
- Conditions
- Hypertrophy, Physiologic Hypertrophy, Physical Activity
- Trial name
- NCT03565302
- Testing
- Formoterol, Terbutaline
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Impaired Mitochondrial Function, Muscle Performance
Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance
As people grow older skeletal muscle gradually becomes smaller and weaker, causing reduced mobility and quality of life. To understand and reverse this negative process investigators need to find new ways of improving the ability…
- Trial name
- Rejuvenate2 (NCT03325491)
- Testing
- Acipimox
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Exeter