Clinical trials: Sinus Pain
Sinusitis, Opioid Use
Pain Control Following Sinus Surgery
Given the ongoing national opioid epidemic, an increased interest has developed in optimizing opioid prescribing practices of physicians, including otolaryngologists.
- Conditions
- Sinusitis, Opioid Use, Opioid Abuse, Narcotic Use
- Trial name
- NCT03783702
- Testing
- OxyCODONE 5 Mg (milligram) Oral Tablet, Ibuprofen 600 Mg (milligram) Oral Tablet, Acetaminophen 650 MG (milligram) Oral Tablet
- Where
- 6 sites in United States, Canada
- Volunteers
- 118 people
- Sponsor
- Stanford University
Arteriovenous Fistula, Pain
Evaluating the Effect of the Valsalva Maneuver on Invasive Pain During Arteriovenous Fistula Cannulation in Hemodialysis Patients
The goal of this clinical trial is to evaluate whether the Valsalva maneuver reduces invasive pain during arteriovenous fistula (AVF) cannulation in adult hemodialysis patients.
- Conditions
- Arteriovenous Fistula, Pain, Hemodialysis Access Failure, Vascular Access Device Complications
- Trial name
- VALPAIN-HD (NCT07066579)
- Testing
- Valsalva Maneuver
- Volunteers
- 60 people
- Sponsor
- Cansu POLAT DÜNYA
Pain, Chronic, Fistula
Effect of Mirror Therapy on the Arteriovenous Fistula Cannulation-related Pain and Anxiety
Pharmacological and non-pharmacological methods are frequently used to reduce cannulation-related pain in patients with fistulas.
- Conditions
- Pain, Chronic, Fistula, Hemodialysis Complication
- Trial name
- NCT06683495
- Testing
- Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Rhinosinusitis
Physiotherapy Protocol in Treating Chronic Rhinosinusitis
This study aims to investigate the effect of adding of integrated physiotherapy program to the conservative medical therapy on quality of life and pressure pain threshold (PPT) in chronic rhinosinusitis patients.
- Trial name
- NCT05442606
- Testing
- Ultrasound Therapy, Manual Drainage Techniques, Self Sinus Massage Technique
- Where
- Saudi Arabia
- Volunteers
- 68 people
- Sponsor
- Cairo University
Hemodialysis Complication, Pain
Determination of the Effect of Cold Needle on Invasive Pain Cannulation
In studies evaluating the methods used to reduce invasive pain associated with cannulation, it is seen that pharmacological and non-pharmacological methods are used.
- Trial name
- NCT06418009
- Testing
- Cold needle application
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul Demiroglu Bilim University
Safety Issues, Efficacy, Self
Lower Silesia Sinus Reducer Registry
Lower Silesia Sinus Reducer Registry is a , single-center, single-arm registry including patients with chronic disabling refractory angina pectoris (Canadian Cardiovascular Society [CCS] classes 2-4) despite maximally tolerated…
- Trial name
- LSSRR (NCT06288165)
- Testing
- Coronary Sinus Reducer Implantation
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Miedziowe Centrum Zdrowia SA
Refractory Angina, Microvascular Angina
Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction.
To demonstrate the feasibility and efficacy of the CS Reducer for the treatment of patients with ischaemia and non-obstructed coronary arteries (INOCA) and coronary microvascular dysfunction (CMD) and through a nested mechanistic…
- Conditions
- Refractory Angina, Microvascular Angina, Microvascular Coronary Artery Disease, Coronary Disease
- Trial name
- REMEDY-PILOT (NCT05492110)
- Testing
- Coronary sinus reducer, Invasive coronary physiology
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Imperial College London
Angina Pectoris, Myocardial Ischemia
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)
VahatiCor's Coronary Sinus Reducer (A-FLUX) has been designed to improve angina or angina-like symptoms in patients with CMD. SERRA-I is an early feasibility study that evaluates the safety and clinical performance of the A-FLUX…
- Conditions
- Angina Pectoris, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases
- Trial name
- SERRA-I US (NCT07449325)
- Testing
- A-FLUX Reducer System
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- VahatiCor, Inc.
Refractory Angina
Use of the Neovasc Coronary Sinus Reducer System for the Treatment of Refractory Angina Pectoris in Patients With Ngina Class 3-4 Who Are Not Candidates for Revascularization
The purpose of this study is to implant the Reducer in patients with the symptoms of refractory angina, that suffer from refractory angina who demonstrate reversible ischemia.
- Trial name
- Reducer (NCT01566175)
- Testing
- Neovac coronary sinus reducer
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hemolysis, Complementary Therapy
The Effect of Coolsense Method on Pain and Comfort in Hemodialysis Patients
This study aimed to investigate the impact of the CoolSense method on arteriovenous fistula cannulation pain and the comfort levels of hemodialysis patients.
- Conditions
- Hemolysis, Complementary Therapy, Pain, Comfort
- Trial name
- NCT06144801
- Testing
- CoolSense Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Karadeniz Technical University
Perianal Fistula
This Study Compares the Conventional Cutting Seton Technique and a GLUBRAN®-Coated Seton in High Perianal Fistula Treatment. The Study Aims to Determine Whether the GLUBRAN®-Coated Seton Improves Healing, Reduces Postoperative Pain and Recurrence, and Better Preserves Anal Continence.
High anal fistula is a complex anorectal condition that can cause persistent pain, purulent discharge, recurrent infection, and a significant reduction in quality of life.
- Trial name
- NCT07676825
- Testing
- Glubran-coated Seton, Seton
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kasr El Aini Hospital
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Chitosan-Based, Gelatin Sponge and Non-absorbable Nasal Packing After Endoscopic Sinus Surgery
This single-centre prospective study compared three nasal packing materials used after endoscopic sinus surgery (ESS) in adults with chronic rhinosinusitis without nasal polyps: a chitosan-based bioresorbable pack (PosiSep X), an…
- Trial name
- ESSPACK-2024 (NCT07862283)
- Testing
- PosiSep X, Spongostan, Osseous polyvinyl alcohol sinus pack (EON Meditech)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Postoperative Nausea and Vomiting, Pain, Postoperative
Guanfacine for PONV and Pain After Sinus Surgery
Postoperative nausea and vomiting (PONV) and pain are the most common causes of Post Anesthesia Care Unit (PACU) discharge delay, with untreated PONV occurring in 20-30% of post-surgical patients.
- Trial name
- NCT02882854
- Testing
- Guanfacine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Vanderbilt University Medical Center
Headache, Sinusitis
Non-Rhinologic Etiologies of Headaches and Facial Pain in Tertiary Care Setting
The study serves to investigate the type and prevalence of non-rhinologic headaches seen through a academic otolaryngology practice.The study encompasses survey questionnaires, review of CT images, and physical examination/nasal…
- Conditions
- Headache, Sinusitis, Rhinitis, Facial Pain
- Trial name
- NCT00355160
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Penn State University
Pilonidal Cyst, Pain Postoperative
Patients' Quality of Life After Pilonidal Cyst Operations.
Biomedical research consists of two main parts. In the first part, the pilonidal cyst-specific quality of life questionnaire is compiled, adapted, validated, tested for suitability in assessing patients after pilonidal cyst…
- Conditions
- Pilonidal Cyst, Pain Postoperative, Quality of Life
- Trial name
- NCT05982028
- Testing
- Minimally invasive pit-picking surgery, Radical surgical excision without suturing
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Coronary Artery Disease, Angina Pectoris
Impact of Coronary Sinus Flow Reducer on Coronary Microcirculation and Myocardial Ischemia
The increasing number of coronary revascularization procedures, coupled with improvements in drug therapy, has significantly extended the lifespan of patients with coronary artery disease (CAD).
- Trial name
- NCT06266065
- Testing
- Coronary Sinus Reducer
- Where
- Croatia
- Volunteers
- 25 people
- Sponsor
- Clinical Hospital Centre Zagreb
Pain, Arteriovenous Fistula
Breathing Exercise and Invasive Pain at Hemodialysis Patients
Non-pharmacological approaches applied in the prevention of invasive pain due to cannulation in patients treated with arteriovenous fistula and hemodialysis; It is also a cost-effective method that prevents the patient from…
- Conditions
- Pain, Arteriovenous Fistula, Breathing Exercise
- Trial name
- NCT05252377
- Testing
- Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Demiroglu Bilim University
Magnetic Therapy, Rhinosinusitis
Effect of Electromagnetic Therapy on Patients With Chronic Rhinosinusitis.
This study aimed to evaluate the efficacy of Pulsed electromagnetic field (PEMF) for Chronic sinusitis in a randomized, double-blind, placebo-controlled trial.
- Conditions
- Magnetic Therapy, Rhinosinusitis, Headache, Fatigue
- Trial name
- NCT05865613
- Testing
- Pulsed electromagnetic field
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Cairo University