Clinical trials: Shortness of Breath, open to volunteers
Acute Heart Failure (AHF), Dyspnoea
Acute Heart Failure in Elderly Patients Admitted to the Emergency Department with Acute Dyspnea: a Multimarker Approach Prognostic Study
Background and Rationale: Acute dyspnea is a frequent presenting symptom in emergency departments (ED), with acute heart failure (AHF) being the most common cause leading to hospitalization in elderly patients.
- Trial name
- READ-MA-PRONO (NCT06692439)
- Volunteers
- 185 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pulmonary Disease (COPD), Chronic Obstructive
Comparison of Arterial and Capillary Blood Gas Analyses in Patients With Respiratory Distress Due to COPD or APE
The assessment of gas exchange is crucial for the management of patients suffering from respiratory distress due to an exacerbation of chronic obstructive pulmonary disease (COPD) or cardiogenic acute pulmonary edema (APE).
- Trial name
- GAZOCAP (NCT07835945)
- Testing
- Capillary blood gas analysis
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ventilated Patients
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal…
- Trial name
- MODUS (NCT07308171)
- Testing
- Baseline, Installation of high flow humidified air cannula, Nasal air puffs
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Spinal Cord Injury, Cervical Cord Injuries Spinal
Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries
This randomized clinical trial aims to evaluate the effectiveness of combining Low Volume Nose Resistance Breathing Exercises (LVNRBE) with Incentive Spirometry (IS) on respiratory outcomes in patients with cervical spinal cord…
- Trial name
- NCT07645027
- Testing
- Acapella device plus Incentive Spirometry, conventional respiratory physiotherapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
CARDIOMYOPATHY
Combined Effect of Aerobic and Resistance Exercise in Non Ischemic Dilated Cardiomyopathy Patients
This study explores the effects of combined aerobic and resistance exercise in patients with non-ischemic dilated cardiomyopathy (NIDCM).
- Trial name
- NCT07062874
- Testing
- Combined Aerobic and Resistance Exercise, Aerobic Exercise Only
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Patients Undergoing Laparoscopic Inguinal Hernia Repair
The Effect of Cold Vapor on Dyspnea, Thirst, Nausea, and Physiological Parameters in the PACU After Laparoscopic Inguinal Hernia Surgery
Cold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period.
- Trial name
- NCT07273162
- Testing
- Cold Vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- TC Erciyes University
Acute Dyspnea, Acute Respiratory Failure
Diaphragm Response in Elderly for Acute Monitoring
Acute dyspnea is a common cause of emergency department admissions among elderly patients. Acute respiratory failure is often multifactorial and requires rapid and reliable evaluation.
- Conditions
- Acute Dyspnea, Acute Respiratory Failure, Diaphragmatic Ultrasound
- Trial name
- DREAM (NCT07132268)
- Where
- 9 sites in France
- Volunteers
- 145 people
- Sponsor
- Centre Hospitalier de Bethune
Pediatric Pneumonia
Effect of Nurse-Directed Therapeutic Positioning in Children With Pneumonia
Pneumonia is a common respiratory infection in children that may cause respiratory distress and impaired oxygenation. This quasi-experimental study aims to evaluate the effectiveness of nurse-directed therapeutic positioning on…
- Trial name
- NCT07913191
- Testing
- Nurse - Directed Side - Lying Positioning, Nurse - Directed Semi-fowler's positioning
- Volunteers
- 150 people
- Sponsor
- University of Baghdad
COPD, ILD
SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection
This is a prospective observational study that evaluates whether the Shuttle Walking Test (SWT) can predict postoperative symptoms, particularly dyspnea, in patients with chronic respiratory diseases undergoing lung resection.
- Conditions
- COPD, ILD, Bronchiectasis, Lung Cancer NOS
- Trial name
- SWEEP (NCT07102589)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Cancer, Fatigue
The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors
The purpose of this study is to evaluate the effects of Progressive Muscle Relaxation (PMR) exercises and deep breathing exercises on dyspnea, fatigue, and self-care behaviors among cancer patients receiving palliative care.
- Conditions
- Cancer, Fatigue, Palliative Care, Progressive Muscle Relaxation
- Trial name
- NCT07619209
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercises
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara University
Dyspnea
The Impact of Telemedicine, Using the Caller's Mobile Phone Camera, on the Quality of Care Provided to Adult Patients Contacting the 15 Centre for Acute Dyspnea
Dyspnea is the subjective sensation of difficult or uncomfortable breathing. It accounts for approximately 10% of emergency department visits and 8% of calls to Emergency Medical Communication Centers.
- Trial name
- TELEDYS (NCT07726628)
- Testing
- Addition of telemedine to standard medical dispatching process
- Where
- 10 sites in France
- Volunteers
- 778 people
- Sponsor
- Poitiers University Hospital
Shortness of Breath
Effectiveness of a Mastery Learning Education Program for Parents of Children Using Inhaler Therapy in an Emergency Unit
Respiratory diseases account for a significant proportion of pediatric emergency department admissions, and effective management of respiratory conditions in children is crucial.
- Trial name
- NCT07452731
- Testing
- Parent Education Program, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Emine ŞAHİN
Moderate Respiratory Distress, Severe Respiratory Distress
High Flow Nasal Oxygen Therapy an Implementation Study in Pediatric Wards
The purpose of this study is to prospectively evaluate the process of implementing HFNO in several MSF projects, varying according to geographical and programmatic contexts, population, health structures, human resources, and…
- Trial name
- HFNO (NCT06715423)
- Where
- Afghanistan
- Volunteers
- 960 people
- Sponsor
- Epicentre
Pulmonary Disease, Chronic Obstructive (COPD)
Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease is progressive and irreversible respiratory condition characterized by persistent airflow limitation leading to dyspnea and reduced functional capacity.
- Trial name
- NCT07518472
- Testing
- Short term Pulmonary Rehabilitation, Box breathing with short term pulmonary rehabilitation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
COPD
Prospective Dynamic Cohort Study of Phenotypic Profiles in Patients With Chronic Obstructive Pulmonary Disease
This prospective, multicenter, real-world observational cohort study will describe phenotypic profiles, patient characteristics, and treatments in adults with stable chronic obstructive pulmonary disease (COPD).
- Trial name
- COPD-BPCO 2 (NCT07627763)
- Testing
- Routine care / no study-specific intervention
- Where
- 7 sites in France
- Volunteers
- 500 people
- Sponsor
- Initiatives Bronchopneumopathie Chronique Obstructive (BPCO)
Acute Respiratory Failure, Respiratory Insufficiency
HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport
The HERMES Phase III study is an international, multicenter, prospective observational investigation designed to characterize the quality and safety of patient transport during advanced respiratory support.
- Conditions
- Acute Respiratory Failure, Respiratory Insufficiency, Respiratory Distress, Critical Illness
- Trial name
- HERMES (NCT07805603)
- Testing
- Advanced Respiratory Support During Patient Transport
- Where
- 4 sites in Colombia, Egypt and 2 more
- Volunteers
- 565 people
- Sponsor
- Medipol University
Work of Breathing
The Role of Breathing Perception in Respiratory Control
Warfighters are frequently exposed to environments and life-support systems that increase breathing resistance and the work of breathing (WOB), such as aircraft on-board oxygen generation systems and underwater breathing…
- Trial name
- NCT07470099
- Testing
- Ambient Noise, Increased Auditory Feedback, Noise Distraction
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Indiana University
Bronchiectasis
Effects of Energy Conservation Techniques With Pursed Lip Breathing on Quality of Life in Bronchiectasis
Bronchiectasis is the abnormal dilatation of the bronchi. Due to airway dilatation patient is unable to clear the mucus and risk of infection is increased.
- Trial name
- NCT06995989
- Testing
- energy conservation techniques with pursed lip breathing, pursed lip breathing
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Dyspnea
Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.
- Trial name
- NCT06336642
- Testing
- SPOT-ON Early Start, SPOT-ON Delayed Start
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Cystic Fibrosis (CF), Cystic Fibrosis in Children
Physical Impairments in Children With Cystic Fibrosis
It is aimed to reveal impairments regarding urinary incontinence, dyspnea, muscle strength, functional capacity or quality of life in children and adolescents with cystic fibrosis compared to healthy children and adolescents.
- Trial name
- NCT06984679
- Testing
- Physical Evaluations in Children with Cystic Fibrosis, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Democracy University