Clinical trials: Sexual Desire Disorder
Breast Carcinoma, Cervical Carcinoma
Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer
This phase II randomized trial studies how well bupropion hydrochloride works in improving sexual desire in women with breast or gynecological cancer.
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Ovarian Carcinoma, Postmenopausal
- Trial name
- NCT03180294
- Testing
- Bupropion 150 mg XL
- Where
- 362 sites in United States
- Volunteers
- 230 people
- Sponsor
- NRG Oncology
Sexual Dysfunction, Sexual Dysfunctions, Psychological
Mindfulness as Treatment of Sexological Problems
The primary aim of this study is to test Mindfulness in Sex Therapy and Intimate Relationships (MSIR) as an add-on treatment to sex therapy in a clinical sample of patients referred with sexual problems, controlling for time…
- Conditions
- Sexual Dysfunction, Sexual Dysfunctions, Psychological, Sexual Dysfunctions, Physiological
- Trial name
- NCT03775239
- Testing
- Mindfulness in Sex Therapy and Intimate Relationships (MSIR), Treatment-as-usual
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Sexual; Sexual Desire, Illicit Drugs
Chemsex, Perceived Risks and Coping Strategies.
The research hypothesis is that access to prevention and harm and risk reduction associated with the use of psychoactive substances in a sexual context is insufficient for MSM practicing chemsex.
- Conditions
- Sexual; Sexual Desire, Illicit Drugs, MSM
- Trial name
- Chemsex (NCT04584229)
- Testing
- Intervention
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Montpellier
Hypoactive Sexual Desire Disorder
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
The purpose of this study is to determine if the absorption of the testosterone spray is the same as the Intrinsa® Patch.
- Trial name
- NCT01096329
- Testing
- Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1%
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Hypoactive Sexual Desire Disorder
Safety and Efficacy of LibiGel® for Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women
This study is a randomized, double-blind, placebo-controlled, multi-center study of the safety and efficacy of LibiGel 300mcg in the treatment of HSDD in surgically menopausal women.
- Trial name
- BLOOM (NCT00657501)
- Testing
- testosterone gel
- Where
- 69 sites in United States, Canada
- Volunteers
- 575 people
- Sponsor
- BioSante Pharmaceuticals
Breast Cancer, Vulvovaginal Signs and Symptoms
WISH, Feasibility of a Factorial Design
The primary aim of this study is to evaluate the feasibility of testing a multi-component intervention for sexual function using a factorial design.
- Conditions
- Breast Cancer, Vulvovaginal Signs and Symptoms, Sexual Desire Disorder, Body Image
- Trial name
- NCT07023822
- Testing
- Hyaluronic acid (HLA) Vaginal Moisturizer, Polycarbophil Vaginal Moisturizer, Hypnotic Relaxation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Tennessee, Knoxville
Sexual Dysfunction
Efficacy of Tibolone Versus Transdermal E2/NETA on Sexual Function in Naturally Postmenopausal Women (P06089)
Tibolone has been registered for treatment of menopausal symptoms. It is, however, not known what the effects are of tibolone in postmenopausal women diagnosed with sexual dysfunction.
- Trial name
- NCT00413764
- Testing
- tibolone, estradiol-norethisterone
- Volunteers
- 358 people
- Sponsor
- Organon and Co
Hypoactive Sexual Desire Disorder
2. Study to Evaluate the Efficacy/Safety of Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial with an optional Open-label Extension to evaluate the efficacy of bremelanotide (BMT), administered subcutaneously (SC) on an as needed basis for the…
- Trial name
- HSDD (NCT02338960)
- Testing
- Bremelanotide
- Where
- 91 sites in United States, Canada
- Volunteers
- 714 people
- Sponsor
- Palatin Technologies, Inc
Hypoactive Sexual Desire Disorder (HSDD)
Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study
The primary objective is to confirm the efficacy of intravaginal prasterone (DHEA) on Hypoactive Sexual Desire Disorder (HSDD) in postmenopausal women.
- Trial name
- NCT03619005
- Testing
- Prasterone 6.5 mg (0.50%) Vaginal Insert
- Where
- 10 sites in United States
- Sponsor
- EndoCeutics Inc.
Sexual Dysfunctions, Psychological
Uptitration Trial of Flibanserin Versus Placebo in Premenopausal Women With Hypoactive Sexual Desire Disorder
This trial is designed to assess the safety and efficacy of flibanserin in the treatment of premenopausal women with Hypoactive Sexual Desire Disorder (HSDD) that meets standard diagnostic criteria.
- Trial name
- NCT00360555
- Testing
- flibanserin, flibanserin 50mg, flibanserin 100mg
- Where
- 77 sites in United States, Canada
- Volunteers
- 1,584 people
- Sponsor
- Sprout Pharmaceuticals, Inc
Hypoactive Sexual Desire Disorder (HSDD)
Stress Hormones, Mood and Women's Sexual Desire (MODEST)
Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA).
- Trial name
- MODEST (NCT01702818)
- Where
- Canada
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Menopause, Sexual Abstinence
Effects of Tribulus Terrestris in Postmenopausal Women With Hypoactive Sexual Desire Disorder
Hypoactive Sexual Desire Disorder ( HSDD ) is very common in postmenopausal women due to a reduction in circulating androgen levels.
- Trial name
- NCT01975649
- Testing
- Tribulus Terrestris
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Federal University of Minas Gerais
Hypoactive Sexual Desire Disorder (HSDD)
Study to Assess the Efficacy/Safety of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
This study is designed to evaluate efficacy and safety of a testosterone patch as treatment for low libido in naturally menopausal women who are taking estrogen or estrogen/progestin therapy.
- Trial name
- NCT00349791
- Testing
- Testosterone Transdermal System
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 549 people
- Sponsor
- Warner Chilcott
Hypoactive Sexual Desire Disorder
Lybridos in Pre- and Postmenopausal Women With Hypoactive Sexual Desire Disorder Due to Maladaptive Activation of Sexual Inhibitory Systems
A double-blind, randomized, placebo-controlled, dose-finding study to investigate the safety and efficacy of Lybridos in the domestic setting in healthy female subjects with hypoactive sexual desire disorder and maladaptive…
- Trial name
- NCT01743235
- Testing
- Testosterone, Buspirone hydrochloride
- Where
- 12 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Emotional Brain NY Inc.
Hypoactive Sexual Desire Disorder
Lybridos in Pre-and Postmenopausal Women With Hypoactive Sexual Desire Disorder
A double-blind, randomized, placebo-controlled, dose-finding study to investigate the safety and efficacy of Lybridos in the domestic setting in healthy female subjects with hypoactive sexual desire disorder and maladaptive…
- Trial name
- NCT02101203
- Testing
- 0.5 mgTestosterone + 10 mg Buspirone
- Where
- 10 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emotional Brain NY Inc.
Sexual Dysfunctions, Psychological
Study of Pharmacological Treatment in Women With Female Sexual Interest/Arousal Disorder (FSIAD).
This clinical trial is a prospective, randomized, double-blind Phase III study with two arms to determine the efficacy and safety of the use of an IPDE in women with FSIAD.
- Trial name
- FSIAD (NCT04433559)
- Testing
- Tadalafil 1,5 mg oral tablets
- Volunteers
- 80 people
- Sponsor
- Lidia Larrañaga
Hypoactive Sexual Desire Disorder
Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)
The primary objective is to confirm the efficacy of intravaginal prasterone (DHEA) on Hypoactive Sexual Desire Disorder (HSDD) in postmenopausal women.
- Trial name
- NCT03287232
- Testing
- Prasterone 6.5 mg (0.50%) Vaginal Insert
- Where
- 69 sites in United States, Canada
- Volunteers
- 653 people
- Sponsor
- EndoCeutics Inc.
Hypoactive Sexual Desire Disorder
Safety and Efficacy of LibiGel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women
This study is a randomized, double-blind, placebo-controlled, multi-center study of the safety and efficacy of LibiGel® 300mcg in the treatment of HSDD in surgically menopausal women
- Trial name
- BLOOM (NCT00613002)
- Testing
- testosterone gel
- Where
- 63 sites in United States, Canada
- Volunteers
- 597 people
- Sponsor
- BioSante Pharmaceuticals
Sexual Dysfunctions, Psychological, Hypoactive Sexual Desire Disorder
Bupropion in Sexual Dysfunction Among Methadone Maintenance Treatment Men
The purpose of this study is to assess the tolerability, safety, and efficacy of bupropion hydrochloride sustained-release in the treatment of sexual dysfunction in men on methadone maintenance therapy.
- Conditions
- Sexual Dysfunctions, Psychological, Hypoactive Sexual Desire Disorder, Erectile Dysfunctions
- Trial name
- NCT02593396
- Testing
- Bupropion hydrochloride sustained-release
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- University of Malaya
Hypoactive Sexual Desire Disorder
Testosterone in Female Hypoactive Sexual Desire Disorder
The success of sildenafil in the treatment of erectile dysfunction has led to efforts to find similar treatments for prevalent disorders of female sexual dysfunction.
- Trial name
- NCT00140153
- Testing
- testosterone gel (Androgel)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Beersheva Mental Health Center