Clinical trials: Sex Differences
25(OH)D Measurement and 25(OH)D Deficiency
LC-MS/MS 25(OH)D Status in a Large Cohort
The present study assessed serum 25(OH)D in a cohort of 74235 outpatients by liquid-chromatography-tandem-mass-spectrometry (LC-MS/MS).
- Trial name
- NCT03388203
- Testing
- 25(OH)D measurement, PTH measurement
- Volunteers
- 74,235 people
- Sponsor
- Azienda Ospedaliera di Bolzano
Cardiovascular Disease
Sex Differences in Oral Bacteria
Females have a lower incidence of hypertensive and cardiovascular disorders that may relate to differences in nitrogen oxides in the blood and saliva.
- Trial name
- NCT01583803
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Temporomandibular Disorder
Myoelectric Activity and Mandibular Movement for the Diagnosis of Temporomandibular Disorder
This study aimed to provide normal reference values of surface electromyography (sEMG) and mandibular kinematics in Chinese young adults, compare the sex differences and assess the diagnosis value of these indices.
- Trial name
- NCT06372769
- Testing
- electromyograph and kinesiograph
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
HIV
Evaluation of the Quality of Self-collected Blood Spot Specimens for Laboratory HIV Testing - An InvolveMENt Sub Study
We will invite a convenience sample of up to 45 enrolled subjects to participate in an optional, self-administered blood specimen collection procedure to determine optimal procedures for collection.
- Trial name
- NCT02043041
- Testing
- Number of DBS Spots
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Acute Myocardial Infarction
Examining Heart Attacks in Young Women
Heart disease and heart attacks pose a serious health risk to young women, and women tend to experience less successful recoveries after a heart attack than men do.
- Trial name
- VIRGO (NCT00597922)
- Where
- 92 sites in United States
- Volunteers
- 2,985 people
- Sponsor
- Yale University
Sleep
The First-Night Effect and Sex Differences in Strength and Muscular Endurance Performance
Introduction: The first-night effect, characterized by disturbed sleep in an unfamiliar environment, may impair next-day physical performance. However, whether this response differs between men and women remains unclear.
- Trial name
- NCT07758166
- Testing
- First-Night Effect at the laboratory, first-night effect (at home)
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Hemodynamics
The Effect of Age on the Hemodynamic Response During Rest and Exercise in Healthy Humans
Primary: To observe how hemodynamic parameters are affected by age during rest and exercise in healthy humans. Furthermore, how an acute fluid challenge changes hemodynamic parameters.
- Trial name
- HemReX (NCT01974557)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Finn Gustafsson
Healthy Participants
The UBC Long-distance Triathlon Adaptation Study
The purpose of this study is to investigate the effect of 12-months of individualized endurance-training (swimming, cycling and running) on physiological and psychological adaptations in exercise naïve individuals.
- Trial name
- ULTRA (NCT06467656)
- Testing
- Individualized, periodized endurance training for ultra-endurance triathlon., Time-Aligned Control
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Accidental Falls, Falling Injury
The Emergency Department Stopping Elderly Accidents, Deaths and Injuries Program
This study aims to determine if a bedside decision aid used in the ED for mechanical fall prevention can increase patient participation in management options that decrease their fall risk.
- Conditions
- Accidental Falls, Falling Injury, Other and Unspecified Fall on Same Level
- Trial name
- ED-STEADI (NCT02167737)
- Testing
- Bedside Decision Aid, Control Arm
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Lehigh Valley Hospital
Smoking, Cigarette, Smoking E-cigarette
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS.
- Conditions
- Smoking, Cigarette, Smoking E-cigarette, Healthy Volunteer
- Trial name
- NCT03721822
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dental Erosion
Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study
Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion.
- Trial name
- NCT02780973
- Testing
- Wearing of an intraoral device with bovine tooth samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Cardiovascular Diseases
Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women
The purpose of this study is to document differences between men and women in changes in metabolic variables associated with cardiovascular risk in response to a 4 weeks isocaloric controlled nutritional intervention based on the…
- Trial name
- ALIMED (NCT01293344)
- Testing
- Controlled nutritional intervention based on the Mediterranean diet
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Laval University
Healthy
Gender Difference in Response to Caffeine in Children and Adolescents
Caffeine use is on the rise in America, and one of the most popular sources is soda. Among youth ages 8-16, caffeine consumption has increased by over 70% in the past 30 years.
- Trial name
- NCT02119416
- Testing
- Low Caffeine Administration first (1mg/kg body weight), High Caffeine Administration first (2mg/kg body weight)
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Postoperative Delirium (POD), Sex Differences
Sex-Dependent Risk of Postoperative Delirium and Mediating Effects of Family Visits
Postoperative delirium is a common and serious complication after surgery, affecting 10-40% of older patients undergoing non-cardiac procedures.
- Trial name
- NCT07502391
- Where
- Switzerland
- Volunteers
- 471 people
- Sponsor
- Julian Rössler
Obesity
Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery
Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity.
- Trial name
- DIBASH (NCT06538948)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Switzerland
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Alcohol Use Disorder
Sex Differences in the Response to Abstinence From Alcohol.
In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that…
- Trial name
- SPAR (NCT03827460)
- Testing
- Abstinence from alcohol, Usual drinking, Intravenous Alcohol
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Mechanical Neck Pain
Sex-Based Differences in Cervical Joint Position Sense in Patients With Chronic Mechanical Neck Pain
This is across sectional observational study aims to investigate whether there are sex-based differences in cervical proprioception, pain intensity, and neck disability in patients with chronic mechanical neck pain.
- Trial name
- NCT07126418
- Testing
- observation (cervical proprioception, neck pain and neck disability)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Sex
Baroreflex Sensitivity Response to Exercise
Males and females show distinct differences in cardiovascular function, especially during exercise. Evidence suggests that females generally have lower blood pressure due to hormonal influences that reduce blood vessel…
- Trial name
- PACE MAKERS (NCT06709560)
- Testing
- Moderate Intensity Continuous Exercise, Vigorous Intensity Continuous Exercise, Moderate Intensity Continuous Exercise Matched for Blood Pressure
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Acute Myocardial Infarction
Sex Differences in Relative Survival and Excess Mortality Following Acute Myocardial Infarction
The aim of this study was to estimate the impact of sex on relative survival and excess mortality following acute myocardial infarction (AMI) using a population-based cohort within a relative survival framework.
- Trial name
- NCT02952417
- Testing
- Excess mortality
- Volunteers
- 180,000 people
- Sponsor
- University of Leeds
Spinal Stenosis
Surgical Versus Nonsurgical Treatment for Spinal Stenosis
Lumbar spinal stenosis (a narrowing of spaces in the backbone that results in pressure on the spinal cord and/or nerve roots) is a condition that occurs frequently, particularly in the elderly.
- Trial name
- NCT00022776
- Testing
- Surgical decompression, Physical therapy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Pittsburgh