Clinical trials: Sex Differences
HIV
Evaluation of the Quality of Self-collected Blood Spot Specimens for Laboratory HIV Testing - An InvolveMENt Sub Study
We will invite a convenience sample of up to 45 enrolled subjects to participate in an optional, self-administered blood specimen collection procedure to determine optimal procedures for collection.
- Trial name
- NCT02043041
- Testing
- Number of DBS Spots
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Position Sense, Sex Characteristics
Shoulder Proprioception: a Comparative Study on Hand Dominance and Sex
The goal of this cross-sectional study is to examine the differences in proprioception sensation depending on sex and dominant side factors in healthy volunteers.
- Conditions
- Position Sense, Sex Characteristics, Glenohumeral Joint, Upper Extremity
- Trial name
- NCT06602427
- Testing
- Shoulder proprioception measurement using isokinetic dynamometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Myocardial Injury
Propofol Cardioprotection for Type II Diabetics
The purpose of this study is to determine if an intravenous anesthetic with antioxidant properties will protect the heart of diabetic patients from injury while undergoing coronary bypass surgery.
- Trial name
- NCT00734383
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University of British Columbia
Cannabis
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.
- Trial name
- THC-Gender-I (NCT02811510)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Isokinetic Test, Force-velocity Profile
Sex Differences in Knee Strength and Speed in Male and Female Football Players
Force-velocity (F-V) profiling is increasingly used to describe the mechanical capacities of the knee extensors and knee flexors in football, but almost all available reference data come from male players.
- Conditions
- Isokinetic Test, Force-velocity Profile, Soccer Performance, Female Athletes
- Trial name
- NCT07810387
- Testing
- Isokinetic test
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Smoking, Cigarette, Smoking E-cigarette
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS.
- Conditions
- Smoking, Cigarette, Smoking E-cigarette, Healthy Volunteer
- Trial name
- NCT03721822
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Muscle Relaxation, Sex
Sex-related Differences in the Response to the Muscle Relaxant Drug Mivacurium
Muscle relaxants are drugs providing muscle relaxation during surgical treatment. Previous studies have shown that males and females respond differently to this kind of drug.
- Trial name
- NCT01906528
- Testing
- Mivacurium
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Malocclusion, Quality of Life
The Effect of Malocclusions on Oral Health Related Quality of Life
Malocclusions in adolescents may affect oral health related quality of life. The study aims at; 1. Evaluating two instruments measuring oral health related quality of life; "Child Perceptions Questionnaire 11-14" (CPQ 11-14)…
- Conditions
- Malocclusion, Quality of Life, Orthodontics, Adolescent
- Trial name
- NCT05038865
- Testing
- Malocclusion and Orthodontic Treatment
- Where
- 3 sites in Sweden
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Malmö University
Carotid Stenosis
Differences of the Postoperative Outcome for Carotid Surgery Patients Treated by Either Male or Female Surgeons
This research will focus on the differences of the postoperative outcome for carotid surgery patients treated by either male or female surgeons.
- Trial name
- NCT06485102
- Testing
- Carotid Surgery in patients with symptomatic or asymptomatic stenosis
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Augsburg
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Fatigue Syndrome
Exercise-related Post-exertional Malaise
This pilot study is intended to identify sex differences in myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) during recovery from brief but high effort exercise tests.
- Trial name
- CFS/ME (NCT03331419)
- Testing
- Exercise test
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Cardiovascular Diseases, Frailty
Managing Frailty Through Mobilization in Males and Female Inpatients With Cardiovascular Disease
Frailty describes the overall health of a person. Inpatients with cardiovascular problems have a higher risk for frailty - or the sick are more likely to get sicker - causing longer hospital stays, hospital readmission, and…
- Trial name
- NCT06810661
- Testing
- Mobility promotion
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Sherbrooke
Cancer
Mindfulness-Based Art Therapy for Cancer Patients
The purpose of this study is to determine whether cancer patients who receive the mindfulness-based art therapy (MBAT) program demonstrate improvement in health-related quality of life, a reduction in stress-related symptoms, and…
- Trial name
- NCT00034970
- Testing
- Mindfulness-based at therapy
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
HELICOBACTER PYLORI INFECTIONS
Efficacy and Safety of Second-Line Helicobacter Pylori Eradication
Subjects with persistent H. pylori infection after first-line treatment failure receives either a 14-day PPI-based moxifloxacin triple regimen (esomeprazole, amoxicillin, and moxifloxacin) or a 14-day P-CAB-bismuth-containing…
- Trial name
- NCT07855497
- Testing
- P-CAB-BM quadruple regimen, Moxifloxacin triple regimen
- Where
- South Korea
- Volunteers
- 141 people
- Sponsor
- Seoul National University Bundang Hospital
Non-small Cell Lung Cancer
Evaluation of Gender Differences on the Psychosocial and Economic Impact in Patients With Advanced Non-small Cell Lung Cancer
The purpose of this study is to evaluate of gender differences on the psychosocial and economic impact in patients with advanced non-small cell lung cancer.
- Trial name
- IMPULSO (NCT02336061)
- Testing
- Evaluation of gender differences on the psychosocial and economic impact.
- Where
- 18 sites in Spain
- Volunteers
- 344 people
- Sponsor
- Asociación para la Investigación del Cáncer de Pulmón en Mujeres
Elderly, Chronic Pain
Characterization of Chronic Pain in Elderly Population With Emphasis on Differences Between Gender
Introduction: It is estimated that by 2025 there will be approximately 1.2 billion people above 60 years old. Global projections indicate that by 2050 there will be about 2 billion elders, 80% of them living in developing…
- Conditions
- Elderly, Chronic Pain, Gender
- Trial name
- NCT06855797
- Testing
- Observation
- Where
- Brazil
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cardiac Diseases
Health Literacy As a Mediator Between Gender, Illness Identity, and Self-Efficacy
The goal of this observational study is to understand the role of health literacy in shaping the relationship between gender differences, illness identity, and self-efficacy in geriatric patients with cardiac diseases.
- Trial name
- NCT06707116
- Volunteers
- 100 people
- Sponsor
- Cairo University
Melanoma, Lung Cancer
Gender Difference in sidE eFfects of ImmuNotherapy: a Possible Clue to Optimize cancEr tReatment
The study aim is to investigate the differences between sex and gender in the immune-related adverse events (irAEs) development associated with immune checkpoint inhibitors (ICI) treatment.
- Conditions
- Melanoma, Lung Cancer, Head and Neck Cancer, Urogenital Neoplasms
- Trial name
- G-DEFINER (NCT04435964)
- Testing
- Immunotherapy
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Sex Differences in Immune Response, Acute Inflammatory Diseases in Children
Study of the Sex Differences in Inflammatory Diseases in Children
Sexual differences in innate immune response have been demonstrated and were mainly attributed to the influence of the sex steroids (1-18).
- Trial name
- SepsiX (NCT04815811)
- Testing
- Blood collection, Stool collection
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Queen Fabiola Children's University Hospital