Clinical trials: Sevoflurane
Ischemic Heart Disease
Sevoflurane Effect on Left Atrial Performance: A Transoesophageal Echocardiographic Study
The left atrial performance is affected by the preload as well as the afterload. The LA active pumping is increased by stretching of the LA but within limits, after which the active pumping declines.
- Trial name
- NCT03999463
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
General Anesthesia, Geriatric Patient
Sevoflurane and Propofol Anesthesia on Postoperative Delirium
Delirium is defined as an acute onset and fluctuating course of mental status change with inattention and an altered level of consciousness.
- Trial name
- NCT01995214
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Anesthesia, Cancer Recurrence
Effect of Propofol and Sevoflurane Anesthesia on HSP70 Expression in Tumor Cells
The goal of this clinical trial is to learn if sevoflurane-based inhalational anesthesia (s-IA) and propofol-based total intravenous anesthesia (p-TVA) have different effects on HSP70 expression in different types of tumour…
- Conditions
- Anesthesia, Cancer Recurrence, Cancer
- Trial name
- NCT06626711
- Testing
- Propofol, Sevoflurane
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Saint Petersburg State University, Russia
Delirium on Emergence
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
Children who receive general anesthesia may become agitated (emergence delirium) in the recovery period. This occurs more often after inhalational anesthetics, particularly sevoflurane and desflurane than after propofol.
- Trial name
- NCT02111447
- Testing
- Propofol, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
Laparoscopic Surgery
Response Surface Modeling of Remimazolam and Sevoflurane
This prospective randomized open-label study aims to investigate the pharmacodynamic interaction between remimazolam and sevoflurane during general anesthesia using response surface modeling.
- Trial name
- NCT07620782
- Testing
- Remimazolam (Byfavo), Sevoflurane (Volatile Anesthetic)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Pusan National University Yangsan Hospital
Ophthalmic Abnormalities, Pediatric Disorder
Effect of Remimazolam and Sevoflurane Anesthesia on Recovery in Pediatric Patients
The most commonly used anesthetic for general anesthesia in pediatric patients is sevoflurane, an inhalation anesthetic. However, the incidence of emergence agitation after sevoflurane anesthesia in pediatric patients is high…
- Trial name
- NCT06053489
- Testing
- general anesthesia with remimazolam
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Pusan National University Yangsan Hospital
Hypotension Drug-Induced
A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia
The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane.
- Trial name
- NCT06334549
- Testing
- Ephedrine-P, Phenylephrine-P, Norepinephrine-P
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dalian Municipal Central Hospital
Vitreous Detachment
Comparison of Propofol Target Controlled Infusion (TCI) and Sevoflurane
This study was an experimental, single-blinded, randomized controlled trial that aimed to compare recovery time between TCI propofol and sevoflurane.
- Trial name
- NCT04865991
- Testing
- TCI Propofol, Sevoflurane
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
General Anesthesia
Safety and Efficacy of Maintenance of Etomidate in General Anesthesia
This study was designed to use etomidate combined with sevoflurane intravenously to maintain anesthesia process under the monitoring of BIS. Propofol was used as the controls.
- Trial name
- NCT05223907
- Testing
- Etomidate, Propofol
- Where
- China
- Volunteers
- 1,080 people
- Sponsor
- Henan Provincial People's Hospital
Unrecognized Condition
Effectivity Gas Extraction to Prevent Anesthesiologists Waste Gas Exposure of Sevofluorane During Pediatric Induction
Inhalational anesthetics (IAs) are widely used in surgery and experimental research. IAs, in addition to their medical significance, are a major source of chemical contamination in the operating rooms (ORs).Exposure to IAs in ORs…
- Trial name
- NCT06487169
- Testing
- Urine analysis to determine the presence of hexafluoroisopropanol
- Volunteers
- 10 people
- Sponsor
- Bnai Zion Medical Center
Sevoflurane, Lidocaine
Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy
This study will be conducted to evaluate the effects of different anesthetic modalities [sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)] on intracranial pressure…
- Conditions
- Sevoflurane, Lidocaine, Propofol, Intracranial Pressure
- Trial name
- NCT07062367
- Testing
- Propofol, Sevoflurane plus lidocaine infusion, Sevoflurane
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Anesthesia, Infertility
Sevoflurane Versus Propofol; Neuro Endocrine Response in Patients of Oociyt Pick up
Patients in the study will be grouped as 1st group Propofol, 2nd Group Sevofluran.Preoperative blood will be taken from the patients and cortisol, acth, glucagon, aldosterone, PGE2, CRH will be studied.
- Conditions
- Anesthesia, Infertility, Pain, Postoperative, Stress, Psychological
- Trial name
- NCT03507621
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Orak
Anesthesia, Hypoventilation
Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric Surgery
Determine the incidence of early post-operative hypoventilation in post-anesthesia care unit (PACU) in patients undergoing laparoscopic bariatric surgery under opioid-sparing compared with sevoflurane-based anesthesia.
- Conditions
- Anesthesia, Hypoventilation, Opioid Use, Bariatric Surgery
- Trial name
- NCT05962671
- Testing
- Opioid-sparing based anesthesia, Sevoflurane-based anesthesia
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Tanta University
Occupational Exposure
Sevoflurane Human Biomonitoring in Operating Room Personnel
Sevoflurane is a widely used volatile agent for induction and maintenance of anaesthesia. The administration of sevoflurane involves the risk of occupational exposure.
- Trial name
- NCT03891316
- Testing
- HFIP and Sevoflurane are measured after 3 consecutive days of work.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Inhalation Anesthesia, Lung Injury
The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain…
- Trial name
- NCT04645316
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Brain Injury
Sevoflurane Sedation on Intra Cranial Pressure in Traumatic Brain Injury Patients
Main purpose of the study is to evaluate the effect of sevoflurane on intra cranial pressure (ICP) after traumatic brain injury.
- Trial name
- SEPIA (NCT01374633)
- Testing
- 1: Sevoflurane
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delayed Graft Function, Renal Outcome After Kidney Transplantation
Volatile Anesthetic Protection Of Renal Transplants 2
To compare the effect of a sevoflurane based anesthesia versus a propofol based anesthesia on the incidence of DGF in recipients of kidneys of donation after circulatory death (DCD) and donation after brain death (DBD) donors
- Conditions
- Delayed Graft Function, Renal Outcome After Kidney Transplantation, Acute Rejection (AR) of Transplanted Kidney, Graft Survival
- Trial name
- VAPOR-2 (NCT02727296)
- Testing
- sevoflurane, propofol
- Where
- 5 sites in Denmark, Netherlands and 2 more
- Volunteers
- 488 people
- Sponsor
- University Medical Center Groningen
Oxygen Saturation
Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation.
- Trial name
- NCT02834845
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ufuk University
Surgical Conditions
Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.
A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia.
- Trial name
- BLISS4 (NCT03170661)
- Testing
- Deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 98 people
- Sponsor
- Leiden University Medical Center
Invasive Cancer, Pediatric Cancer
Comparing TIVA Using Propofol or Dexmedetomidine Versus Sevoflurane During Anaesthesia of Children Undergoing Bone-Marrow Aspiration
No doubt that children facing surgical procedures are subjected to perioperative distressing, anxious and worrying periods. Several factors included; parental deprivation, anxiety, previously mismanaged experience and…
- Trial name
- NCT05636566
- Testing
- Sevoflurane, Propofol infusion for maintance, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University