Clinical trials: Seroma
Umbilical Hernia Repair
Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical Hernia
Umbilical hernia is a type of ventral hernia that occurs commonly in adulthood, and mesh reinforcement is well established since there is a reduced recurrence rate when compared to suture repair.
- Trial name
- NCT07845370
- Testing
- Topical Tranexamic Acid Spray, No Topical Tranexamic acid
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Dr Mudassar Saeed Pansota
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Breast Cancer - Female
Effects of Negative Pressure Wound Bandaging After Mastectomy
Participant information sheet: Mastectomy is a surgical method used to treat breast cancer. A mastectomy involves the removal of the entire breast. A common postoperative complication after a mastectomy is seroma, i.e.
- Trial name
- NEPTAM (NCT07607366)
- Testing
- PICO negative pressure wound therapy by Smith and Nephew
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Dalarna County Council, Sweden
Seroma Formation
Effect of Irrigation of Triamcinolone Versus Hypertonic Saline in Decreasing Seroma Post Abdominoplasty
A total of 90 abdominoplasty patients were randomly assigned into three groups: Group A: Triamcinolone group, Group B: Hypertonic saline group, Group C: Control group Randomization: It was performed using the closed envelope…
- Trial name
- NCT07733921
- Testing
- Irrigation of Triamcinolone, Hypertonic Saline 10%, Control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Seroma
Doxycycline Use in Post-Operative Seromas
Seromas are collections of serous fluid that can develop following surgical procedures and may persist as fibrous-lined pseudocysts if not adequately treated.
- Trial name
- NCT07498010
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Cesarean Section, Surgical Site Infection
Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions
This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery.
- Conditions
- Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
- Trial name
- STRIP-CS (NCT07686913)
- Testing
- Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Riverside University Health System Medical Center
Drainage, Seroma
Effect of Drainage on the Incidence of Seroma After Laparoscopic Trans Abdominal Preperitoneal Inguinal Hernia Repair
The aim of the study is to evaluate the effect of drainage on the incidence of seroma after laparoscopic transabdominal preperitoneal inguinal hernia repair.
- Conditions
- Drainage, Seroma, Laparoscopic, Trans-abdominal
- Trial name
- NCT07681700
- Testing
- Trans-abdominal preperitoneal repair + Drainage, Trans-abdominal preperitoneal repair
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Surgical Site Infection (SSI), Wound Healing Complication
Prophylactic Use of ciNPWT in Gynecologic Laparotomy
This is a prospective, open-label, non-randomized interventional feasibility study with a nested qualitative analysis. The study exploratively verifies the feasibility of targeted prophylactic closed incision negative pressure…
- Conditions
- Surgical Site Infection (SSI), Wound Healing Complication, Seroma, Hematoma
- Trial name
- NCT07645547
- Testing
- closed incision negative pressure wound therapy (ciNPWT)
- Volunteers
- 30 people
- Sponsor
- University Hospital Hradec Kralove
Postoperative Hematoma, Postoperative Seroma
Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy
Gender affirming surgeries (GAS) have been steadily increasing in the US, with the gender affirming mastectomy (GAM) being the most common surgery performed.
- Trial name
- IVTXA (NCT05794321)
- Testing
- Intravenous TXA
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Parotid Neoplasms, Post-operative Complications
Swedish National Parotidectomy Study (SNaPs): Drainless Versus Standard Surgery
The purpose of this study The purpose of this study is to find out if it is safe to perform surgery on the parotid gland (the large salivary gland in front of the ear) without using a wound drain.
- Conditions
- Parotid Neoplasms, Post-operative Complications, Seroma as Procedural Complication
- Trial name
- SNaPs (NCT07620184)
- Testing
- Active wound drainage (Standard of Care), Omission of active wound drain
- Where
- 3 sites in Sweden
- Volunteers
- 600 people
- Sponsor
- Uppsala University Hospital
Modified Radical Mastectomy, Drain Effect
Active Drainage vs. Passive Drainage in MRM
The aim of the study is to compare between active drainage and passive drainage in post-operative seroma formation after modified radical mastectomy in female patient with breast carcinoma as regard of: Primary Outcomes: 1.
- Conditions
- Modified Radical Mastectomy, Drain Effect, Seroma Formation, Brest Cancer
- Trial name
- MRM Drains (NCT07621575)
- Testing
- compare active and passive drain
- Where
- Egypt
- Volunteers
- 157 people
- Sponsor
- MOHAMED GAMAL AHMED ARAKEEB
Post-operative Seroma Formation, Breast Cancer Surgery
EFFECT OF DAFLON (DIOSMIN AND HESPERIDIN) ON POST-OPERATIVE SEROMA FORMATION IN BREAST CANCER SURGERY''
Post-operative seroma formation remains one of the most common complications following breast cancer surgery. This prospective randomized controlled trial was conducted to evaluate the efficacy of Micronized Purified Flavonoid…
- Trial name
- seroma (NCT07588828)
- Testing
- Daflon (Diosmin and Hesperidin)
- Where
- Pakistan
- Volunteers
- 190 people
- Sponsor
- Ittefaq Hospital trust
Inguinal Hernia, Chronic Pain
3-point With 1-point Mesh Fixation in TAPP for Inguinal Hernia
This study was designed to compare the outcome of 3 point with 1 point lightweight mesh fixation in TAPP surgery for patients with inguinal hernia. The main outcome include seroma, chronic pain, recurrence, et al.
- Conditions
- Inguinal Hernia, Chronic Pain, Seroma, Recurrent
- Trial name
- NCT06314152
- Testing
- Lightweight mesh fixation in 3 points or 1 point
- Where
- China
- Volunteers
- 351 people
- Sponsor
- Nanchong Central Hospital
Seroma Following Procedure, Infections
Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy
Normally, after this surgery, skin is stitched in the usual simple way, with no quilting, and two drains are put in to remove serosa, one under the arm and one on the chest.
- Conditions
- Seroma Following Procedure, Infections, Pain, Postoperative
- Trial name
- SVDD (NCT07512141)
- Testing
- Double drains will be placed, A single drain will be placed
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Amputation, Amputation; Postoperative, Sequelae
Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound…
- Conditions
- Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma
- Trial name
- PREVENA-AMP (NCT03773575)
- Testing
- PREVENA™ PEEL & PLACE™ Dressing Kit
- Where
- 3 sites in United States, Italy
- Volunteers
- 272 people
- Sponsor
- Thomas Jefferson University
Postoperative Seroma Rate, Drainage Tube Removal Time, and Capsular Contracture Rate, Seroma Following Procedure
Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants
Brief Summary This study hypothesizes that in immediate breast reconstruction following tumor resection, the application of inactivated Pseudomonas aeruginosa preparation (PAP) may reduce infection rates by decreasing…
- Trial name
- RCT of PAI + P (NCT07460297)
- Testing
- Pseudomonas aeruginosa, Povidone-Iodine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jianyi Li
Surgical Wound Infection, Hematoma
Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG
This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1.
- Conditions
- Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay
- Trial name
- CABG (NCT07355452)
- Testing
- Multi-layer closure (MLC), singlelayer closure for leg wound
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Breast Cancer, Mastectomy
Local Compression Seroma DIminution Objective (CLODIS)
This study evaluates the impact of local compression by chest bandage on the number of seroma punctures in patients treated by mastectomy with or without lymphadectomy.
- Conditions
- Breast Cancer, Mastectomy, Seroma
- Trial name
- CLODIS (NCT03598712)
- Testing
- Compression by chest bandage urgo K2®, punctures
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Francois Baclesse
Seroma, Lumbar Spine Decompression
Management of Seroma After Posterior Lumbar Spine Decompression
The aim of this study is to evaluate the clinical presentation and management strategies of seroma formation following posterior lumbar spine decompression.
- Trial name
- NCT07060781
- Testing
- Posterior Lumbar Spine Decompression
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kafrelsheikh University
Hernia Inguinal
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery
This study is comperative study between TAPP And Lichtenstein Techniques for Inguinal Hernia surgery.The Lichtenstein tension-free open hernioplasty involves placing a tailored polypropylene mesh over the inguinal canal defect…
- Trial name
- NCT07067281
- Testing
- Lichtenstein Tension-Free Mesh Hernioplasty, Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College