Clinical trials: Septic Arthritis
Spondylarthropathies
Mechanism of Action of Anti-IL17 Therapy in Peripheral Spondyloarthritis
The purpose of this study is to determine the mechanism of action on target tissue level of anti Interleukine-17 (anti-IL-17) an therapy in peripheral spondyloarthritis.
- Trial name
- MoA aIL-17 (NCT03358134)
- Testing
- Secukinumab
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Osteo Arthritis, Cellulitis
Continuous Regional Anesthesia for Septic Limb Orthopedic Surgery
This study aims to assess the safety of using continuous regional anesthesia for post-operative analgesia during septic limb orthopedic surgery.
- Trial name
- ACOSM (NCT01947660)
- Testing
- Systemic analgesia + Continuous regional anesthesia, Systemic analgesia
- Where
- France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Strasbourg, France
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Septic Arthritis
Diagnostic Criteria for Septic Arthritis
Septic arthritis (SA) is a rare but highly disabling disease. The ideal diagnosis criteria is not well established. There is an urgent need to establish golden standard for diagnosis.
- Trial name
- NCT05790434
- Testing
- Laboratory test, History taking and physical examination, biopsy
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoarthritis, Septic Arthritis
Analysis of Human Knee Joint Fluid Using Metabonomic, Genomic and Tribology Techniques
Making the diagnosis underlying a painful, swollen joint currently involves aspiration followed by numerous microbiological and biochemical laboratory tests.
- Conditions
- Osteoarthritis, Septic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT02565160
- Testing
- Intra-articular aspiration of Joint, Joint irrigation washout, Total Joint Arthroplasty
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Imperial College London
Joint Infection, Septic Arthritis
Utilization of Leukocyte Esterase in the Diagnosis of Pediatric Joint Infections
Pediatric joint infections are a common diagnostic dilemma encountered by treating orthopaedic surgeons. No single test is sensitive or specific enough to stand alone in determining the presence of joint infection.
- Trial name
- NCT02032732
- Testing
- leukocyte esterase test
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Tennessee
Septic Arthritis, Gait Disorder, Sensorimotor
Clinical Utility of Exoskeleton Robot Training in Patients With Septic Arthritis After a Thermal Injury: A Case Report
Bone and/or joint infections, such as septic arthritis (SA), are rare, but delayed diagnosis or improper treatment can result in irreversible joint destruction.
- Trial name
- NCT05886166
- Testing
- robot assisted training
- Volunteers
- 2 people
- Sponsor
- Hangang Sacred Heart Hospital
Hip Effusion, Septic Arthritis
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
- Conditions
- Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
- Trial name
- NCT05971745
- Where
- 6 sites in United States, Australia
- Volunteers
- 161 people
- Sponsor
- Connecticut Children's Medical Center
Joint Effusion
Use of Infrared Spectroscopy in Septic Arthritis Diagnosis
The main objective of this study is to assess the ability of Fiber-optic Evanescent Wave Spectroscopy (FEWS) to discriminate synovial fluids samples of septic arthritis patients from other causes of joint effusion by analyzing ex…
- Trial name
- SynoFAST (NCT02860871)
- Testing
- infrared spectroscopy
- Where
- France
- Volunteers
- 611 people
- Sponsor
- Rennes University Hospital
Septic Arthritis
Ultrasonography Assessment of Septic Arthritis on Native Joint
The aim of this trial is to study the interest of ultrasonography among patients with septic arthritis. Currently, ultrasonography is useful for detecting small fluid effusions, for examining otherwise inaccessible joints, such…
- Trial name
- SEPT'ECHO (NCT02018952)
- Testing
- Ultrasonography assessment
- Where
- 3 sites in France
- Volunteers
- 28 people
- Sponsor
- Nantes University Hospital
Arthritis
External Validation of a Septic Arthritis Prognosis Score
Observational study
- Trial name
- SYNOLACTATES + (NCT03819855)
- Where
- France
- Volunteers
- 244 people
- Sponsor
- Rennes University Hospital
Inflammatory Disease, Rheumatoid Arthritis
Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19
People with inflammatory diseases are often treated with medications that act to suppress the immune-system, increasing the risk of catching infections.
- Conditions
- Inflammatory Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- OPINION (NCT05115370)
- Testing
- Semi-structured qualitative interview
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Gonococcal (GC) Infection, Arthritis, Infectious
Epidemiology of Gonococcal Arthritis (EpGAr)
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals.
- Trial name
- EpGAr (NCT06897943)
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Septic Arthritis of the Native Hip, Epiphyseal Arrest, Lower Leg
Mid-term Results of Epiphyseal Transfer for Hip Post Septic Epiphyseal Loss
Absence or loss of the growth plate together with the epiphysis of a long bone presents a very difficult condition to treat. An example of this is the loss of the head and neck of the femur especially as a part of severe sequelae…
- Trial name
- NCT07321418
- Volunteers
- 20 people
- Sponsor
- Assiut University
Septic Arthritis, Inflammatory Arthritis
Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis
The purpose is to found new biomarker that differentiate septic arthritis and Juvenile Idiopathic Arthritis in children. Synovial liquid and blood samples with proteomic, MiRNA searching, multiplex cytokine analysis and cellular…
- Conditions
- Septic Arthritis, Inflammatory Arthritis, Children
- Trial name
- DIANE (NCT03827759)
- Where
- 5 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Travelers' Diarrhea, Functional Bowel Disorders
Trial Evaluating Chemoprophylaxis Against Travelers' Diarrhea - Prevent TD
The purpose of this study is to develop evidence on the relative efficacy of 2 rifaximin chemoprophylaxis regimens for the prevention of Travelers' Diarrhea (TD) in a deployed setting.
- Conditions
- Travelers' Diarrhea, Functional Bowel Disorders, Reactive Arthritis
- Trial name
- NCT02498301
- Testing
- Rifaximin
- Where
- 6 sites in United States, Kenya
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Joint Effusion, Septic Arthritis
Development and Validation of a Simple Diagnostic Tool Predictive of the Aseptic Character of Joint Effusion
Development and validation of a simple diagnostic tool predictive of the aseptic character of joint effusion in the primary care setting.
- Conditions
- Joint Effusion, Septic Arthritis, Arthritis
- Trial name
- PRASEPT (NCT03979937)
- Testing
- Arthrocentesis
- Where
- France
- Volunteers
- 328 people
- Sponsor
- Centre Hospitalier le Mans
Ultrasound Therapy; Complications, Septic Arthritis
Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee
Primary objective: Description of ultrasound abnormalities seen in native septic arthritis of the knee during each visit. Primary endpoint: Describe the ultrasound abnormalities observed on Day 0, Day 10, 6 weeks, 3 months, 6…
- Conditions
- Ultrasound Therapy; Complications, Septic Arthritis, Knee Arthritis
- Trial name
- USAK (NCT04952220)
- Testing
- ultrasound
- Where
- 7 sites in France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Fever, Respiratory Tract Infections
A Retrospective, Blinded Validation of a Host-response Based Diagnostics
This is a retrospective, blinded, external validation study of a novel in-vitro diagnostic (IVD) assay that will include samples that were previously collected from febrile pediatric patients.
- Conditions
- Fever, Respiratory Tract Infections, Urinary Tract Infections, Gastroenteritis
- Trial name
- PATHFINDER (NCT01911143)
- Where
- 2 sites in Israel
- Volunteers
- 600 people
- Sponsor
- MeMed Diagnostics Ltd.
Septic Arthritis
The Predictive Role of C-reactive Protein to Albumin Ratio (CAR) in the Treatment of Septic Arthritis in Young Chlidren
Purpose: C-reactive protein to albumin ratio (CAR) has emerged as a novel marker of inflammation. However, almost no research has evaluated the role of CAR in septic arthritis (SA).
- Trial name
- NCT06241365
- Volunteers
- 82 people
- Sponsor
- wangxiaodong