Clinical trials: Self-harm
Suicide
Suicide Re Attempts in Young Adults After First Suicide Attempt : Socio-demographic, Clinical and Biological Correlates
Suicide is the second leading cause of death among people aged 15 to 24 (WHO, 2014). After a first suicide attempt, the 18 to 25 years old would be very likely to repeat the act: 25 to 31% would make a new attempt in the…
- Trial name
- SURAYA (NCT03538197)
- Testing
- clinical and biological correlates
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hôpital le Vinatier
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depressive Disorder, Major, Suicide
Rapid Acting TMS for Suicide Ideation in Depression
This study evaluates the effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), on the neural networks underlying explicit and implicit suicidal cognition…
- Trial name
- NCT05100004
- Testing
- Accelerated Theta Burst Stimulation
- Where
- United States
- Sponsor
- Stanford University
Trichotillomania, Excoriation (Skin-Picking) Disorder
Internet CBT for Trichotillomania and Skin Picking Disorder
The primary aim of the study is to test the feasibility, safety and efficacy of a manual based, Internet-delivered, behavior therapy (I-BT) for trichotillomania and skin picking disorder.
- Trial name
- NCT04559750
- Testing
- Internet delivered behavior therapy (I-BT)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Self Harm
Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study
The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions.
- Trial name
- NCT06317155
- Testing
- Occupational therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University
Suicidal Ideation, Major Depressive Disorder
Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
The purpose of this study is to gather information regarding the use of a new type of transcranial magnetic stimulation (TMS) called theta burst stimulation (TBS) for suicidal ideation in adolescents with Major Depressive…
- Trial name
- NCT04502758
- Testing
- MagVenture TMS Therapy System w/Theta Burst Stimulation
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Suicide, Attempted, Suicidal Ideation
Clinical Decision Support to Prevent Suicide
Suicide kills 132 Americans every day. The first step of suicide prevention is risk identification and prognostication. Researchers like this study team have developed and validated predictive models that use routinely collected…
- Trial name
- CDS_PS (NCT05312437)
- Testing
- Interruptive Alert, CDS, Passive Prompt, CDS
- Where
- United States
- Volunteers
- 596 people
- Sponsor
- Vanderbilt University Medical Center
Suicidal Ideation, Suicide
The Impact of Ketamine on the Reward Circuitry of Suicidal Patients
Every 40 seconds, someone in the world dies by suicide. There is a lack of effective and safe antisuicidal agents for preventing suicide attempts.
- Trial name
- NCT02532153
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Bipolar Disorder (BD), Suicidality
Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression
Bipolar disorder is characterized by manic episodes and episodes of extreme depressive feelings, also known as bipolar depression (BD).
- Trial name
- DEEPP (NCT05177146)
- Testing
- Intravenous Ketamine (IV)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Addiction and Mental Health
Suicide, Suicidal Ideation
Intervening to Reduce Suicide Risk in Veterans With Substance Use Disorders
The purpose of this study is to evaluate the impact of a Cognitive Behavioral Therapy (CBT) intervention compared to a Supportive Psycho-educational Control (SPC) condition in reducing the frequency and intensity of suicidal…
- Conditions
- Suicide, Suicidal Ideation, Substance-Related Disorders
- Trial name
- NCT02439762
- Testing
- Cognitive Behavioral Therapy (CBT), Supportive Psycho-education (SPC)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Suicide, Attempted
Pilot Trial of Inpatient Cognitive Therapy for the Prevention of Suicide in Military Personnel
The broad objective of this research is to effectively utilize a unique window of opportunity during the hospitalization period following a recent suicide attempt to deliver a brief and targeted intervention for traumatized…
- Trial name
- CDMRP (NCT01356186)
- Testing
- Post Admission Cognitive Therapy (PACT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Suicide
Veterans Coping Long-term With Active Suicide
The proposed study seeks to test the efficacy of an intervention to reduce suicide behaviors in Veterans. The Veterans Coping Long Term with Active Suicide Program (CLASP-VA) is an innovative, telephone-based intervention that…
- Trial name
- CLASP-VA (NCT01894841)
- Testing
- Coping Long Term with Active Suicide (CLASP), Safety Assessment and Follow Up Evaluation
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
NSSI
The Muti-centered Investigation，Pathogenesis and Intervention Study of Non-suicidal Self-injury Behavior in China
Non-suicidal self-injury (NSSINSSINSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT04094623
- Testing
- Dialectical behavior therapy, Social support group therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing Medical University
Suicide, Engagement, Patient
The BH-Works Suicide Prevention Program for Sexual and Gender Minority Youth
Youth suicide is a serious public health concern. Compared to their heterosexual and cisgender peers, sexual and gender minority (SGM) adolescents report higher rates of suicidal ideation and suicide attempts.
- Trial name
- NCT05922670
- Testing
- The Behavioral Health-Works Suicide Prevention Program for Sexual and Gender Minority Youth
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Virginia Polytechnic Institute and State University
Depression, Anxiety, Self-Injurious Behavior
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
The investigators examined whether brief, app-based interventions were helpful in alleviating mental health symptoms during the transition to college.
- Trial name
- NCT06348277
- Testing
- Mindfulness plus mood monitoring, Mood monitoring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Suicide
Alaska Native Collaborative Hub for Resilience Research
The goal of the Alaska Native Resilience Research Study (ANRRS) is to identify community-level protective factors that can most effectively reduce co-occurring youth suicide and alcohol risk.
- Trial name
- ANCHRR (NCT03131739)
- Volunteers
- 585 people
- Sponsor
- University of Alaska Fairbanks
Family Conflict, Suicidal Ideation
Early Intervention for Suicide Risk Among Immigrant Youth
The purpose of this project is to develop and test a family-based preventive intervention for suicide risk among 1st and 2nd generation immigrant Latino/a adolescents.
- Trial name
- NCT03221530
- Testing
- Early Intervention for Suicide Risk Among Immigrant Youth, Enhanced usual care
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
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