Clinical trials: Sedative During Endoscopy
Endoscopy, Colonoscopy
Can Nitrous Oxide (Laughing Gas) be Used as a Sedative for GI Endoscopy Procedures?
Nitrous oxide (commonly known as 'laughing gas') is often used during dental and other outpatient procedures, because it is easy to administer, is short-acting and rapidly clears from the body following the procedure.
- Trial name
- NCT05396144
- Testing
- 5% inhaled nitrous oxide, 50% inhaled nitrous oxide
- Where
- United States
- Sponsor
- Stanford University
Endoscopy
Effect of the Antihistamine Injection to Prevent Paradoxical Reaction During Sedative Endoscopy
This single-blind prospective study is aimed to investigate the effect of antihistamine as an adjunctive sedative for the patients with histories of severe paradoxical reaction to midazolam during sedative endoscopy.
- Trial name
- NCT03940391
- Testing
- Chlorpheniramine and midazolam, Midazolam
- Where
- South Korea
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Upper Airway Obstruction, Apnea, Obstructive
Improve Oxygenation and Capnographic Detection During Sedative EGD
The purpose of this study is to compare the effect of mandibular advancement bite block and high flow nasal cannula to standard bite block for oxygenation, capnographic measurement, prevention of hypoxemia, intervention events…
- Trial name
- NCT03138850
- Testing
- Olympus standard bite block, YX mandibular advancement bite block, Optiflow High flow nasal cannula
- Where
- Taiwan
- Volunteers
- 170 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Unconsciousness, Apnea, Postanesthetic
Race-Specific Propofol Titration to Effect for Procedural Sedation
Prospectively evaluate newly established guidelines and make clinicians aware of inter-racial difference in propofol sensitivity.
- Conditions
- Unconsciousness, Apnea, Postanesthetic, Sedative Overdose, Hypoxemia
- Trial name
- NCT03290859
- Testing
- Titrate propofol monotherapy infusion to effect
- Where
- United States
- Volunteers
- 2,780 people
- Sponsor
- University of Florida
Sedation and Analgesia, Cholangiopancreatography, Endoscopic Retrograde
EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives
Recording and analyzing electroencephalogram (EEG) and continuous pain monitor data under anesthesia in order to investigating the pharmacodynamic effects of opioids and sedatives.
- Conditions
- Sedation and Analgesia, Cholangiopancreatography, Endoscopic Retrograde, Anesthesia, General
- Trial name
- SED-ERCP (NCT07211828)
- Testing
- high dose of alfentanil, low dose of alfentanil with propofol
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chi Kwan Fung
Endoscopic Hemostasis, Sedation
Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding
Remazolam besylate was used for sedation during endoscopic hemostasis in patients with esophageal and gastric varices rupture and bleeding in liver cirrhosis.
- Trial name
- NCT05554965
- Testing
- Propofol, Remimazolam besylate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Renmin Hospital of Wuhan University
Sedative Effect During Drug-induced Sleep Endoscopy, Obstructive Sleep Apnea (OSA)
Combination of Remimazolam and Propofol During Drug-induced Sleep Endoscopy
This study helps patients find the optimal sedation regimen in drug-induced sleep endoscopy
- Trial name
- NCT06784479
- Testing
- Remimazolam and Propofol, Propofol, Midazolam and propofol
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Dan Liu