Clinical trials: Sedation and Analgesia Monitoring
Sedation and Analgesia Monitoring
Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk
Intraoperative hypotension is a common situation. It increases postoperative morbidity and mortality, especially in patients at high postoperative risk undergoing high-risk surgery.
- Trial name
- OPTI-TWO (NCT05893030)
- Testing
- anesthesia guided by sedation and analgesia monitoring, anesthesia performed according only to the clinical judgment of the anesthetist as usual practice
- Where
- 20 sites in France
- Volunteers
- 1,132 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Analgesia, Sedation
Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients
The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the…
- Conditions
- Analgesia, Sedation, Mechanical Ventilation, Pain
- Trial name
- NCT00789412
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
Procedural Sedation and Analgesia, Pediatric ALL
Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring
This is a prospective, monocentric diagnostic study aiming to evaluate whether a sedation score obtained by a per-procedural electroencephalogram (EEG), the PSI score, could identify patients for whom a 2 μg/kg dose of DEX would…
- Trial name
- DINAMO (NCT06867289)
- Testing
- EEG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Pain
Bispectral Index as an Analgesia Monitoring in Severely Ill Patient: Effect of Remifentanyl
The aim of this protocol is to study the prophylactic effect of remifentanil on bispectral index variation during a nociceptive stimuli.
- Trial name
- NCT00162591
- Testing
- remifentanyl
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Failure of Respiratory Function
Evaluation of Pupillary Distension Reflexes, as a Tool for the Monitoring of Analgesia for Patients in Intensive Care.
Sedation-analgesia is an important therapy for patients in resuscitation. It requires a surveillance, in order to avoid excessive or insufficient dosages of sedative or nonmorphinics, sources of side effects.
- Trial name
- PUPILLO REA (NCT02843893)
- Testing
- Measure the minimum intensity of a painful stimulation
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Grenoble
Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia
qNOX Response to Nociceptive Motor Events During Procedural Sedation
The goal of this observational study is to evaluate whether the CONOX monitor can detect pain during sedation in patients undergoing urological procedures.
- Conditions
- Monitoring Noxious Events Using EEG-Derived Pain Indices, Procedural Sedation and Analgesia, Monitored Anesthesia Care
- Trial name
- MO-NOX (NCT07413848)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health