Clinical trials: Sedation Protocols
Severe Pneumonia
The Application of Different Sedation Protocols in ICU Patients With Severe Pneumonia
This study collected data from patients with severe pneumonia to compare the duration of mechanical ventilation under different sedation regimens in real-world settings.
- Trial name
- ICU (NCT06514781)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Xiangya Hospital of Central South University
Hypercatabolism, Sedative, Hypnotic, or Anxiolytic Use Disorders
Sedation Protocols and Skeletal Muscle Metabolism in Mechanical Ventilated Patients
To investigate the effects of different sedation protocols on skeletal muscle metabolism in mechanical ventilated patients in ICU.
- Trial name
- NCT03402113
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Chinese Medical Association
Pain
Pain Evaluation During Follicle Aspiration: Comparison of Two Sedation Protocols
Giving infiltration analgesia around the neck of the womb (= paracervical block, PCB) is frequently experienced as a painful procedure by women undergoing follicle aspiration.
- Trial name
- NCT00742807
- Testing
- Low dose of alfentanil hydrochloride, Normal dose of alfentanil hydrochloride
- Where
- Belgium
- Sponsor
- University Hospital, Ghent
Fiberoptic Bronchoscopy
Determination of Fiberoptic Bronchoscopy Sedation Protocols in Turkey
Fiberoptic bronchoscopy (FOB), which is difficult to tolerate while awake, is recommended to be performed by the patient under sedation.
- Trial name
- NCT06000995
- Testing
- Survey Questions
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Samsun University
Atrial Fibrillation (AF), PFA
Electrophysiologist-led Deep Sedation Protocols for Pulsed Field Ablation for Atrial Fibrillation Using a Bipolar Tip-Catheter: The DEEP-PFA Randomized Controlled Trial
The DEEP-PFA trial is an investigator-initiated, prospective, single-center, three-arm (1: 1: 1), randomized controlled study comparing three anesthesia regimens-midazolam + fentanyl (DS1), flurbiprofen + midazolam + fentanyl…
- Conditions
- Atrial Fibrillation (AF), PFA, Deep Sedation
- Trial name
- NCT07149545
- Testing
- Arm A (Fentanyl + Midazolam), Arm B (Flurbiprofen axetil + Fentanyl + Midazolam), Arm C (Fentanyl + Dexmedetomidine)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Anzhen Hospital
Anxiety Disease
Comparative Evaluation of Three Anxiety Control Protocols in Third Molar Extraction
The surgery for the extraction of the third molars is a procedure in Dentistry that generates a large picture of anxiety in the patient. One of the ways to try to soften this picture, are the professionals to use sedation.
- Trial name
- NCT03165500
- Testing
- Diazepam, Midazolam, Nitrous Oxide + Oxygen Gas
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Mechanical Ventilation, Analgesia
Improving Adherence to the Sedation-analgesia Protocol in Pediatric Intensive Care
Sedation-analgesia is a major concern in the management of children in pediatric intensive care units (PICUs). International guidelines recommend the use of sedation-analgesia protocols, as their implementation has already proven…
- Conditions
- Mechanical Ventilation, Analgesia, Nurse Training
- Trial name
- SEDATIDE2 (NCT07038850)
- Testing
- Multimodal nurse training about nurse driven sedation-analgesia protocol
- Where
- 2 sites in France
- Volunteers
- 285 people
- Sponsor
- Hospices Civils de Lyon
Critical Illness
Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol.
The purpose of this study is to determine whether the use of both a nurse-driven sedation protocol and daily sedative interruption, compared with a sedation protocol alone, result in better outcomes for mechanically ventilated…
- Trial name
- SLEAP (NCT00675363)
- Testing
- Protocolized Sedation, Protocolized sedation, with daily interruption
- Where
- 16 sites in United States, Canada
- Volunteers
- 410 people
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
Comparison of Two Different Sedation Protocols During Transvaginal Oocyte Retrieval
The effects of two different sedation protocols during transvaginal oocyte retrieval will be investigated on propofol consumption as a rescue sedative and on IVF success.
- Trial name
- NCT03362021
- Testing
- transvaginal oocyte retrieval
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Attikon Hospital
Minimally Invasive Fetoscopic Procedures
Comparing Fetoscopic Surgery Protocols
Determine surgeon and patient satisfaction with remifentanil-dexmedetomidine (REMI) and dexmedetomidine-fentanyl (DEX) sedation protocols in pregnant patients undergoing minimally invasive fetoscopic procedures
- Trial name
- NCT05654064
- Testing
- Remifentanil-dexmedetomidine, Dexmedetomidine-fentanyl
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Satisfaction, Complication
CO2 Versus O2 Insufflation During ERCP Depending on Sedation Protocols
Endoscopic retrograde cholangiopancreatography(ERCP) and related procedures can cause abdominal pain and discomfort. Some clinical trials have indicated, using the visual analogue scale (VAS) score, that CO2 insufflation during…
- Trial name
- NCT01761474
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Soon Chun Hyang University
Critical Illness, Mechanical Ventilation
Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol
All critically ill, mechanically ventilated patients in the Intensive Care Unit receive medications to relieve pain and anxiety.
- Trial name
- NCT00298493
- Testing
- Sedation management strategy
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Mount Sinai Hospital, Canada
Pain
Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
The purpose of this study is to determine whether ketamine, midazolam, and meperidine are more effective than midazolam and meperidine alone for procedural sedation and analgesia in pediatric digestive endoscopy.
- Trial name
- NCT01168492
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Université de Montréal
Colonoscopy, Ketamine
Comparison of Efficacy of Anesthesia Administered by Endoscopist or Anesthesiologist on Colonoscopy
In sedation applications performed by an endoscopist or anesthetist during colonoscopy, it was investigated whether there were differences in pain levels evaluated by VAS (Visuel analog scale), patient satisfaction, duration of…
- Conditions
- Colonoscopy, Ketamine, Fentanyl
- Trial name
- NCT03607110
- Testing
- Ketamine, fentanyl, patient control analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Selda KAYAALTI
Respiration Disorders
Effectiveness of Sedation Management in an Australian Intensive Care Unit
Sedation is an important treatment when caring for the critically ill patient on a respirator. Adequate sedation has been found to reduce stress, promote relaxation, induce amnesia, improve the tolerance of the respirator, and…
- Trial name
- NCT00202319
- Testing
- Sedation management protocol
- Where
- Australia
- Volunteers
- 316 people
- Sponsor
- Melbourne Health
Propofol, Dexmedetomidine
Impact of Two Different Types of Sedation on ICEB
The QT interval is a measure of the combination of cardiac depolarization and repolarization as it encompasses both the QRS complex and the J-T interval.
- Conditions
- Propofol, Dexmedetomidine, Electrophysiological Balance Index, QT Interval, Variation in
- Trial name
- NCT05757063
- Testing
- Sedation with propofol, sedation with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Respiratory Failure
Pilot Study on Pairing Sedation Strategies and Weaning
A three-arm, randomized, pilot study, to assess the feasibility for the analgesia-first sedation (AFS) study arm/intervention (Fentanyl push first).
- Trial name
- NCT02219659
- Testing
- Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- MemorialCare Health System
Procedural Sedation, Gastrointestinal Endoscopy
Ketodex Versus Ketofol in Adolescent Gastrointestinal Endoscopy
Gastrointestinal endoscopic procedures in adolescents require effective sedoanalgesia to ensure procedural comfort and prevent agitation.
- Trial name
- NCT07401914
- Testing
- Ketodex, Ketofol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Giresun University
Daily Sedative Interruption, Sedation Strategies
Pilot Study for Sedation Interruption in Children
The purpose of this study is to estimate the hypothesized benefit of sedation interruption protocol on mechanical ventilation duration and PICU length of stay.
- Conditions
- Daily Sedative Interruption, Sedation Strategies, Sedation Protocols, Mechanical Ventilation
- Trial name
- NCT02426320
- Testing
- Sedation Interruption Protocol, Standard Sedation Protocol
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Davinia Withington