Clinical trials: Sedation Complication
Sedation Complication
Validation of a Processed EEG Device for Monitoring Sedation in PICU
The goal of this prospective observational study is to validate pEEG as a monitoring tool for the analgosedation level in mechanically-ventilated critically ill children, receiving or not-receiving NMBAs.
- Trial name
- NCT05969483
- Testing
- pEEG monitoring
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera di Padova
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
Intubation Complication
Interest of Instantaneous Fluctuations of Pupillary Diameter for Pain Evaluation in Intensive Care Sedated Patients.
New pain assessment parameter, called the Variation Coefficient of Pupillary Diameter (VCPD) described. This parameter allows evaluating the pain of patients during uterine contractions in obstetrical labor, and postoperatively…
- Trial name
- NCT05633069
- Testing
- Datas analysed by medical records
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Nephrogenic Diabetes Insipidus
Nephrogenic Diabetes Insipidus During Prolonged Sevoflurane Sedation in the ICU: a Retrospective Analysis
The investigators aim to retrospectively explore the electronic medical records of all patients who were admitted to the Intensive Care Unit (ICU) of the UZ Brussels in the last 10 years (March 1st 2011- March 1st 2021) and who…
- Trial name
- NCT04939753
- Testing
- Sevoflurane
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Universitair Ziekenhuis Brussel
Disorder; Mental, Sedative, Depressed Level of Consciousness
Use of Bispectral Index Monitoring to Detect Deep Sedation in Mechanically Ventilated Patients: Validity Study
In the previous study, the investigators obtained the cutoff value of Bispectral Index to detect early deep sedation in patients with mechanical ventilation.
- Conditions
- Disorder; Mental, Sedative, Depressed Level of Consciousness, Mechanical Ventilation Complication, Psychosis Associated With Intensive Care
- Trial name
- NCT02439840
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Capital Medical University
Nociceptive Pain, Sedation Complication
Nociception Evaluated by the NOL® Index in Sedated Patients in the Intensive Care Unit
Due to their underlying pathology and the necessary complicated procedures to which they are exposed, patients in the intensive care unit experience varying degrees of pain at some point in their evolution.
- Trial name
- NCT05399758
- Testing
- NOL monitor
- Where
- 2 sites in Chile
- Sponsor
- University of Chile
Sedation Complication
Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery
Preoperative, intraoperative and postoperative management of the patient are some of the main stages that can affect the hospital LOS and ICU LOS.
- Trial name
- LOS (NCT05809518)
- Testing
- Propofol injection, Dexmedetomidine injection, Dexmedetomidine and Propofol
- Where
- Ukraine
- Volunteers
- 194 people
- Sponsor
- Anesthesia Research Group UA
Brain Network Connectivity, Postoperative Delirium
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor.
- Conditions
- Brain Network Connectivity, Postoperative Delirium, Dexmedetomidine, Propofol
- Trial name
- NCT06138340
- Testing
- Dexmedetomidine, Propofol, Remimazolam Injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Pregnancy, Abdominal, Termination of Pregnancy
TENS for Suction Evacuation for Termination of 1st Trimester Pregnancies
To study the effectiveness of the pain relief method of transcutaneous electrical nerve stimulation (TENS) for women who will undergo suction evacuation under conscious sedation for first trimester termination of pregnancy.
- Conditions
- Pregnancy, Abdominal, Termination of Pregnancy, Pain, Nerve
- Trial name
- NCT03494842
- Testing
- Transcutaneous nerve stimulation (TENS)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Complication
Midazolam With Meperidine and Dexmedetomidine vs. Midazolam With Meperidine and Propofol for Sedation During ERCP
This is a single-center, prospective, randomized, double-blinded study of consecutive patients referred for ERCP. A recent study suggested that the addition of dexmedetomidine to the midazolam-meperidine regimen (MMD)provided…
- Trial name
- NCT02475824
- Testing
- Midazolam®, "Meperidine" (pethidine®), Propofol®
- Where
- South Korea
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Dankook University
Sedation Complication, Acute Respiratory Distress Syndrome Due to COVID-19
Assessment of Sedation Depth Using Processed EEG in ICU Patients With ARDS Receiving Neuromuscular Blockade: A Prospective Observational Study"
"In intensive care units, therapeutic paralysis has been a routine treatment method for many years in a select group of patients.
- Conditions
- Sedation Complication, Acute Respiratory Distress Syndrome Due to COVID-19, Anesthesia Awareness
- Trial name
- NCT06337877
- Testing
- Depth of sedation monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Tepecik Training and Research Hospital
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau