Clinical trials: Sedation Complication
ARDS, Respiratory Effort
Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)
The objective of this research is to utilize respiratory effort parameters as a tool to assist in adjusting sedative drug levels for patients undergoing mechanical ventilation in the intensive care unit, in comparison to the…
- Conditions
- ARDS, Respiratory Effort, Mechanical Ventilation Complication, Sedation
- Trial name
- NCT06242236
- Testing
- The respiratory effort parameters guide sedative dosage.
- Where
- Thailand
- Volunteers
- 156 people
- Sponsor
- Ramathibodi Hospital
Urolithiasis
Comparison of General Anaesthesia and Sedation on the Stone Fragmentation in Lithotripsy
The aim of the study is to compare the impact intravenous sedation versus general anesthesia on the efficacy of stone fragmentation in extracorporeal shock wave lithotripsy treatment.
- Trial name
- NCT01361516
- Testing
- Anaesthesia and Lithotripsy
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Hadassah Medical Organization
Intubation;Difficult, Awake Intubation
Airtraq Versus Fiberoptic for Awake Tracheal Intubation
The airway management is a vital act in anesthesia. The gold standard technique for planned very difficult intubation is nasotracheal fiberoptic intubation. The success rate with this procedure is 98.8%.
- Conditions
- Intubation;Difficult, Awake Intubation, Airway Complication of Anesthesia
- Trial name
- NCT03539185
- Testing
- Videolaryngoscope Airtraq, Fiberoptic bronchoscope
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Caen
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Uremia
BCD to Measure the ED95 of Remimazolam-Assisted Sedation in Arteriovenous Fistula Creation Surgery
This study intends to measure the ED95 of remimazolam-assisted sedation in arteriovenous fistula creation by BCD.
- Trial name
- BCD (NCT06998732)
- Testing
- remimazolam sedation
- Volunteers
- 40 people
- Sponsor
- Gang Chen
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Anesthesia, Sedation
EEG-Guided Sedation in ERCP Procedures
Patients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease.
- Conditions
- Anesthesia, Sedation, Sedation Complication, Anesthesia, Intravenous
- Trial name
- ERCP-EEG (NCT06866886)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Osteoarthritis, Pain, Postoperative
Premedication with Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty
This study aims to find out if preoperatively given dexmedetomidine is effective analgesic adjuvant for treating postoperative pain in patients undergoing elective total knee arthroplasty (TKA).
- Trial name
- TKADEX (NCT04859283)
- Testing
- Dexmedetomidine
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Pain, Chronic
Impact of Sedation on Patient Satisfaction, Radiation Exposure, and Complications in Lumbar Transforaminal Epidural Steroid Injections: A Retrospective Cohort Study
Radicular low back pain due to disc herniation is frequently observed. There are rest, medical treatments, physical medicine modalities, interventional procedures for pain and surgical options in the treatment of lumbar disc…
- Trial name
- NCT06539390
- Testing
- Transforaminal Epidural Injections?
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postoperative Pain
Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates
Newborn infants experience pain after surgical procedures,prevention and management of pain in neonates is important due to its deleterious consequences.
- Trial name
- NCT05324891
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Complication of Anesthesia
End Tidal Carbon Dioxide in Minimal Sedation
This randomized controlled study investigated the effect of end-tidal carbon dioxide monitoring in pediatric patients undergoing minimal sedation.
- Trial name
- ETCO2 (NCT04868266)
- Testing
- end tidal carbon dioxide monitoring
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Seoul National University Hospital
Remimazolam, Anesthesia Awareness
The Effect of Wavelet Index in Monitoring the Sedation Depth of Remimazolam Besylate
To explore the sedative effect of remimazolam in patients undergoing spinal anesthesia without pain stimulation. Both the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) and the Wavelet index (WLi) were used to…
- Conditions
- Remimazolam, Anesthesia Awareness, Sedative, Hypnotic, or Anxiolytic Withdrawal
- Trial name
- NCT06427785
- Testing
- Remimazolam besylate
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Cerebral Tumor
The Effects of Gabapentin Premedication on Neurosurgery
The study is to observe the effects of gabapentin premedication on postoperative pain,vomiting and nausea in patients undergoing neurosurgery. 100 neurosurgical patients are randomized into groups gabapentin(GG) or placebo(GP).
- Trial name
- NCT02306278
- Testing
- gabapentin, vitamin capsules
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Capital Medical University
Respiratory Distress Syndrome in Premature Infant
Respiratory Effect of the LISA Method With Sedation by Propofol Versus Absence of Sedation.
The investigators propose to evaluate premedication with Propofol compared to a control strategy including a placebo with a possible rescue treatment with ketamine to ensure pain control before LISA Procedure .
- Trial name
- PROLISA (NCT04016246)
- Testing
- Propofol-Lipuro
- Where
- 13 sites in France
- Volunteers
- 233 people
- Sponsor
- University Hospital, Grenoble
Retinopathy
Anesthesia for Retinopathy of Prematurity
Premature infants experience more respiratory problems after surgical procedures. The investigators aimed to compare general anesthesia with sedation on the need for post-operative mechanical ventilation in infants undergoing…
- Trial name
- NCT01955135
- Testing
- Ketamine, Sevoflurane, propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Pain, Procedural, Procedural Anxiety
Evaluating the Feasibility of VR for Pediatric Renal Biopsies
The purpose of this study is to assess the use of virtual reality (VR) as an adjunct or alternative to pharmacologic sedation in pediatric patients undergoing renal biopsy.
- Conditions
- Pain, Procedural, Procedural Anxiety, Sedation Complication
- Trial name
- NCT05267704
- Testing
- Oculus Go Virtual Reality Headset
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Emergence Delirium
Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
Emergence delirium (ED) refers to a wide variety of behavioural disturbances that are commonly seen in children following emergence from anesthesia.
- Trial name
- NCT00885443
- Testing
- Propofol, sevoflurane
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain
Vitamin D Supplementations and Postoperative Pain
In this study, effect of vitamin D supplementation on postoperative pain and sedation-agitation will investigate. Children with mental motor retardation between 7-17 age which dental treatment will be performed under general…
- Trial name
- NCT02664857
- Testing
- Vitamin D
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cukurova University
Sedation Complication
Comparison of Emergence/Dysphoric Reaction Frequency of Using 2 Different Doses Ketamine
The aim of this study is to compare the effect of using different doses of ketamine on producing dysphoric reaction.
- Trial name
- NCT05786365
- Testing
- Ketalar 50 MG/ML Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Aksaray University Training and Research Hospital