Clinical trials: Sedation, Bronchoscopy
Hypoventilation
Capnography Monitoring in the Bronchoscopic Sedation
Procedure sedation of flexible bronchoscopy (FB) comforts patients undergoing FB. Hypoventilation during FB is a concern. The investigators investigate the feasibility of monitoring capnography in FB sedation.
- Trial name
- NCT02848118
- Testing
- A nasal-oral cannula of capnography, Observer Assessment of Alertness and Sedation scale
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- Chang Gung Memorial Hospital
Lung Cancers, Peripheral Pulmonary Nodules
General Anesthesia vs Conscious Sedation for Radial Endobronchial Ultrasound
The endoscopic investigation of lung lesions is experiencing significant growth with the increasing number of lung cancer screening programs.
- Trial name
- RESSOURCE (NCT06950515)
- Testing
- Peripheral EBUS under Concious sedation, Peripheral EBUS under General Anesthesia
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Sedation, Tolerance
Randomized Study With Midazolam for Sedation in Flexible Bronchoscopy
The Flexible Bronchoscopy (FB) is a diagnostic and therapeutic procedure which is not usually tolerated by the patient. This makes the examination more difficult and a repetition of the examination, if necessary, resulting in a…
- Conditions
- Sedation, Tolerance, Anxiety, Satisfaction
- Trial name
- NCT01038882
- Testing
- Midazolam, Physiological serum
- Where
- Spain
- Volunteers
- 238 people
- Sponsor
- Hospital Universitario La Fe
Sufentanil, Remifentanil
Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation
The best opioid for bronchoscopy is still unclear.This randomized double-blind prospective study was conducted on a total of 60 patients who were randomly allocated into 3 groups: Group S received sufentanil 0.1 mcg/kg, Group F…
- Conditions
- Sufentanil, Remifentanil, Fentanyl, Bronchoscopy
- Trial name
- NCT03901716
- Testing
- Sufentanil, Fentanyl, Remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Fiberoptic Bronchoscopy
50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
Fiberoptic bronchoscopy may generate pain, anxiety or cough and dyspnea. It may then induce discomfort and then run down its yield.
- Trial name
- NCT00392522
- Testing
- 50% Nitrous Oxide and 50% Oxygen (MEOPA)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Bronchoscopy
This Study Will Evaluate the Effectiveness of a Simple Intervention Through a Classical Yankauer Oral Suction Tube, in Decreasing the Sedative Medication Doses Needed to Provide Effective Patient Sedation During Bronchoscopy, Along With Its Effect on Both Patient's and Bronchoscopist Satisfaction
The aim of this study is to evaluate the effectiveness of a simple intervention through a classical Yankauer oral suction tube, a device known to have a proven safety profile in multiple healthcare settings, in decreasing the…
- Trial name
- NCT06908109
- Testing
- Yankauer Suction Device, Bronchoscopy
- Volunteers
- 120 people
- Sponsor
- American University of Beirut Medical Center
General Anesthesia and Bronchoscopy Sedation
A Non-intervention Fiberoptic Bronchoscopy Study of Remazolam Toluene Sulfonate for Injection Under General Anesthesia and Fiberoptic Bronchoscopy
This is a non-interventional study of remazolam toluenesulfonate (rebenin ®) for injection in Chinese patients. A total of 1000 patients were enrolled in this study based on the preliminary safety assessment of rebenin ®, and all…
- Trial name
- NCT05549791
- Testing
- Remimazolam Tosilate for Injection
- Where
- China
- Volunteers
- 1,285 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Sedation
Alternative Sedation During Bronchoscopy
This protocol hopes to determine whether the use of dexmedetomidine-ketamine can reduce the use of standard of care fentanyl-midazolam sedation during bronchoscopy.
- Trial name
- DEX (NCT01158820)
- Testing
- Dexmedetomidine load, Ketamine load, Midazolam load
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Monitored Anesthesia Care, Respiratory Monitoring
Importance of Integrated Pulmonary Index in Pediatric Bronchoscopy
Integrated Pulmonary Index (IPI) is a tool that provides numerical values on a scale of 1-10 based on physiological parameters such as peripheral oxygen saturation (SpO2), pulse rate, respiratory rate, end-tidal carbon dioxide…
- Trial name
- NCT05137587
- Testing
- Integrated Pulmonary Index (IPI) monitoring, propofol, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Difficult Airway, Postoperative Memories
Postoperative Memories and Level of Sedation for Tracheal Intubation Using Fiberoptic Bronchoscopy/Videolaryngoscopy
Antecedentes In patients with expected difficult airways undergoing surgery, tracheal intubation must be performed with a fiberoptic bronchoscope or video laryngoscope while keeping the patient awake and under the effects of…
- Conditions
- Difficult Airway, Postoperative Memories, Tracheal Intubation
- Trial name
- NCT06514690
- Testing
- Sedation
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Bronchoscopy, Sedation
Sedation Strategies for Therapeutic Bronchoscopy
Therapeutic bronchoscopy is a common procedure to treat respiratory diseases. The procedure includes stent implantation, bronchus dilation, electronic incision, laser therapy, and so on.
- Trial name
- NCT03406546
- Testing
- Dexmedetomidine, Remifentanil, Laryngeal mask
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Changhai Hospital
Flexible Bronchoscopy, Sedation
Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl-sedation for Flexible Bronchoscopy: A Randomized, Single Blind, Controlled Study of Satisfaction and Safety.
Flexible bronchoscopy almost always requires sedation to be successful. In order to increase the availability of propofol for sedation, non-anaesthesiologist administered propofol sedation has been suggested as an alternative to…
- Conditions
- Flexible Bronchoscopy, Sedation, Satisfaction, Safety
- Trial name
- NCT02226328
- Testing
- Propofol sedation, Midazolam and Fentanyl sedation
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Copenhagen University Hospital at Herlev
Lung Cancer
The Role of Sedation Technique in EBUS-TBNA
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy.
- Trial name
- NCT02245295
- Testing
- Moderate Sedation for EBUS/TBNA, General anesthesia for EBUS/TBNA
- Where
- Switzerland
- Volunteers
- 232 people
- Sponsor
- University of Zurich
Bronchoscopy
Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Preventing hypoxemia is one of the major goal of studies for bronchoscopic sedation. Dexmedetomidine is a sedative agents via α2 adrenergic agonist, with little respiratory suppression.
- Trial name
- NCT03521505
- Testing
- Dexmedetomidine arm, Propofol arm
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Recovery
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Bronchoscopy is a promising technology for lung and bronchus disease detection and therapy. However, this procedure is associated with a relatively high risk of hypoxemia, coughing, wheezing, and dyspnea.
- Trial name
- NCT05643066
- Testing
- 0.1 mg/kg esketamine, 0.2 mg/kg esketamine, 0.9% saline
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Fujian Provincial Hospital
Bronchoscopy, Anesthesia
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy
Very often patients receive medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00306722
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 25 sites in United States
- Volunteers
- 250 people
- Sponsor
- Eisai Inc.
Bronchoscopy, Procedural Sedation
Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy
Bronchoscopy may cause coughing, discomfort, body movement, and changes in breathing or blood pressure. Propofol is commonly used for sedation during bronchoscopy, but it may cause respiratory depression, circulatory depression…
- Trial name
- NCT07744061
- Testing
- Ciprofol, Propofol, Sufentanil
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Central Hospital
Bronchoscopy, Conscious Sedation
Sedation During Bronchoscopy:Dexmedetomidine vs Alfentanil
The purpose of this study is to find the best sedation necessary for patients undergoing bronchoscopy. Patients are randomized to three different regimes of sedation during bronchoscopy were studied: 1.
- Trial name
- NCT01805726
- Testing
- xylocain, Alfentanil, Dexmedetomidine
- Where
- Lebanon
- Volunteers
- 162 people
- Sponsor
- Saint-Joseph University
Sedation, Flexible Bronchoscopy
Use of Dexmedetomidine for Sedation During Flexible Bronchoscopy in Patients With COPD: A Descriptive Study
To determine safety and effectiveness of dexmedetomidine when administered for conscious sedation during flexible bronchoscopy (FB) in patients with Chronic Obstructive pulmonary Disease (COPD).
- Conditions
- Sedation, Flexible Bronchoscopy, COPD
- Trial name
- NCT00401206
- Testing
- dexmedetomidine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Cooper Norcross Health
Lung Disease
Propofol Versus Midazolam+Alfentanil for Sedation During Bronchoscopy: Comparison by Cutaneous Carbon Dioxide Tension
Although propofol is a popular agent for sedation during flexible bronchoscopy, some clinicians have raised concerns that it may cause greater respiratory drive reduction than more common drugs.
- Trial name
- NCT01289327
- Testing
- Sedation with Propofol or Midazolam+Alfentanil for FFB
- Where
- Israel
- Volunteers
- 115 people
- Sponsor
- Rabin Medical Center