Clinical trials: Secondary Osteoarthritis
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Arthroplasty, Replacement, Hip
A Post Market Clinical Follow-up Study With the aneXys Cup
The purpose of the study is the evaluation of the clinical and radiological short- to long-term safety and performance of the aneXys cup. The data will be used for an ongoing evaluation of the product safety and performance.
- Trial name
- NCT03274830
- Testing
- aneXys
- Where
- 3 sites in Germany
- Volunteers
- 102 people
- Sponsor
- Mathys Ltd Bettlach
Total Knee Arthroplasty Secondary to Osteoarthritis
Continuous Saphenous Block Versus Continuous Femoral Block for Total Knee Arthroplasty
Strength of the Quadriceps Muscle is key to recover from Total Knee Arthroplasty. In this study we compare two techniques for pain control after total knee arthroplasty in terms of preserving the motor function (the strength of…
- Trial name
- NCT01250041
- Testing
- continuous femoral nerve block, continuous saphenous nerve block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Arthropathy of Hip, Hip Replacement
Clinical Study With the RM Pressfit Vitamys Cup in Combination With a Mathys Stem
The purpose of the study is the evaluation of the clinical and radiological short- to long-term safety and performance of the RM Pressfit vitamys cup.
- Trial name
- NCT04322916
- Testing
- RM Pressfit vitamys
- Volunteers
- 675 people
- Sponsor
- Mathys Ltd Bettlach
Primary Osteoarthritis of Hip Nos, Secondary Osteoarthritis of Hip
Randomized Controlled Study Comparing a Short Stem Hip Prosthesis With a Stem of Standard Length
80 patients eligible for a total hip replacement (THR) mainly due to primary osteoarthritis were recruited from the waiting list for hip arthroplasty at a university hospital in Sweden.
- Trial name
- NCT02983526
- Testing
- Total hip replacement (2 different designs)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johan Karrholm
Osteoarthritis,Knee
Multicenter Bone and Joint Health Study
The purpose of this study is to investigate opportunities for prevention and treatment of knee osteoarthritis (OA) by evaluating potentially modifiable risk factors for disease and poor pain and physical function outcomes…
- Trial name
- MOST (NCT03033238)
- Where
- 3 sites in United States
- Volunteers
- 4,185 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Knee Osteoarthritis
A Study Evaluating the Safety and Efficacy of a Second Course of TPX-100 in Subjects Who Previously Received TPX-100 for Patellar Osteoarthritis Involving Both Knees
The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of a second course of TPX-100 administered by intra-articular injection to subjects with osteoarthritis of the knee who participated in…
- Trial name
- NCT02837900
- Testing
- TPX-100 200 mg 4 times weekly for 4 weeks
- Volunteers
- 14 people
- Sponsor
- OrthoTrophix, Inc
Inflammatory Tissue Disorder, Osteoarthritis
Mobile - Bearing Knee Study
To evaluate the safety and efficacy of the Encore Mobile-Bearing Knee.
- Conditions
- Inflammatory Tissue Disorder, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- NCT00765362
- Testing
- Encore Mobile-Bearing Knee
- Where
- 8 sites in United States
- Volunteers
- 419 people
- Sponsor
- Encore Medical, L.P.
Hamstring Shortness
Muscle Energy Technique and Muscle Flexibility
The current study will compare the effect of using the muscle energy technique in 2 different methods on the hamstring muscle flexibility
- Trial name
- NCT06855303
- Testing
- Muscle Energy Teqnique using post isometric relaxation (PIR) principle, Muscle Energy Teqnique using receprocal inhibition (RI) principle, Conventional Treatment group
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Hail
Pain
Continuous Femoral Nerve Block Following Total Knee Replacement
The purpose of this study is to determine if putting local anesthetic-or numbing medication-through a tiny tube next to the nerves that go to the knee will improve pain control during physical therapy, and ultimately improve the…
- Trial name
- NCT00135889
- Testing
- Femoral perineural infusion
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Total Knee Arthroplasty Secondary to Osteoarthritis, 18 Years and Older
Preoperative Genicular Radiofrequency and Functional Outcomes After Total Knee Arthroplasty
Knee osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage wear, leading to pain, stiffness, and joint swelling.
- Trial name
- NCT07727551
- Testing
- Radiofrequency ablation of the genicular nerve, 42 degrees Celsius for 120 seconds
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Anesthesiology department Iris South Hospitals
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System FR
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05926622
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Osteoarthritis, Knee, Knee Osteoarthritis
Baseline Predictors of Response to Radial Pressure Wave Therapy in Knee Osteoarthritis
This observational study aims to identify baseline factors that predict clinical response at six months in patients with knee osteoarthritis treated with radial pressure wave therapy (rESWT).
- Trial name
- PRE-RPWT-OA (NCT07531160)
- Testing
- Radial Pressure Wave Therapy
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Hospital Civil de Guadalajara
Osteo Arthritis Knee
Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA)
Purpose: To evaluate embolization as a treatment for OA related knee pain versus placebo to demonstrate the actual effect of embolization on pain and disability.
- Trial name
- NCT03362957
- Testing
- Geniculate Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of North Carolina, Chapel Hill
Primary and Secondary Osteoarthritis in Hip
"How do Contrast Medias in Bone Cement Affect DXA Measurements After THR"
Joint replacement is a well-documented and cost effective treatment of degenerative diseases in the hip (1,2). There are two different principles of fixation of prosthesis components; cemented and uncemented.
- Trial name
- NCT00473421
- Testing
- Barium Sulphate and Zirconium Oxide
- Where
- Norway
- Sponsor
- Ullevaal University Hospital
Osteoarthritis Of Knee
Geniculate Artery Embolization for the Treatment of Knee Pain
This study is to test a new treatment method, geniculate artery embolization (GAE), to reduce the severity of pain and disability caused by knee osteoarthritis.
- Trial name
- GAE (NCT02850068)
- Testing
- Geniculate Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis
ARTEBONE Bone Void Filler in Arthrodesis Procedure of the Ankle
The purpose of this investigation is to assess safety and performance of ARTEBONE Bone Void Filler in the single arthrodesis procedure.
- Trial name
- NCT02480868
- Testing
- ARTEBONE
- Where
- 5 sites in Finland, Poland
- Volunteers
- 34 people
- Sponsor
- BBS-Bioactive Bone Substitutes Oy
Primary Osteoarthritis, Secondary Osteoarthritis
Anthology Hip Replacement System - Orthopaedic Data Evolution Panel (ODEP) Surveillance Study
This clinical study will verify the clinical and radiographic performance of the prosthesis when used in human subjects over a period of 10 years. All complications will be documented.
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Avascular Necrosis, Primary Total Hip Replacement (THR)
- Trial name
- NCT04425603
- Testing
- Anthology Hip Replacement System
- Where
- 4 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT03547947
- Testing
- Medacta Shoulder System
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Knee Osteoarthritis
Zurich Multiple Endpoint Vitamin D Trial in Knee OA Patients
This is a 2-year double-blind randomized controlled trial in 287 community-dwelling individuals age 60 years or older undergoing uni-lateral total knee replacement due to severe OA of the knee.We compare an oral dose of 2000 IU…
- Trial name
- NCT00599807
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Switzerland
- Volunteers
- 273 people
- Sponsor
- University of Zurich