Clinical trials: Second Stage of Labor
Delivery, 2nd Stage of Labor
Study of the Type of Pushing at Delivery
The objective of this randomized clinical trial is to assess and compare the effectiveness of directed closed-glottis (Valsalva) pushing (pushing while holding one's breath) vs.
- Trial name
- EOLE (NCT02474745)
- Testing
- - Directed open-glottis pushing, Directed closed-glottis pushing
- Where
- France
- Volunteers
- 256 people
- Sponsor
- University Hospital, Clermont-Ferrand
Persistent Occipital Posterior Presentation During Labor Delivery
Trial of Prophylactic Manual Rotation of Persistent Occiput Posterior Presentation During the Early Second Stage of Labor to Reduce Operative Delivery: a Prospective Multicenter Randomized Control Trial
Superiority multicenter prospective randomized study on operative delivery (instrumental delivery or caesarean section) of prophylactic manual rotation in case of persistent occipital posterior presentation during the second…
- Trial name
- PROPOP (NCT02695238)
- Testing
- Prophylactic Manual Rotation of persistent occipital posterior presentation
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Vaginal Delivery, Perineal Tear Resulting From Childbirth
Comparison of Finnish and Viennese Techniques for Perineal Protection in Women During the Second Stage of Labor
The goal of this clinical trial is to find out which method of protecting the perineum during childbirth works better in reducing tears in first-time mothers.
- Trial name
- NCT07537842
- Testing
- Finnish Manual Perineal Protection Technique, Viennese Manual Perineal Protection
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Other
Effect of Peanut Balls Used of the Second Stage of Labor, Pushing Perceptions, Fatigue and Birth Outcomes
This study aims to explore the use of peanut balls during the second stage of labor. It compares three different positions: traditional lithotomy position, lateral position, and lateral position with peanut ball in terms of…
- Trial name
- NCT06312449
- Testing
- The side-lying position with the peanut ball during the second stage of labor., During the second stage, the patient is placed in a lateral position
- Where
- Taiwan
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Tung Yu-Ching
Geographic Atrophy Secondary to Age-related Macular Degeneration
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
This is a clinical study to evaluate the safety, tolerability and efficacy of CTx001, administered via a single subretinal injection, for GA (secondary to AMD).
- Trial name
- Opti-GAIN (NCT07392255)
- Testing
- CTx001
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 75 people
- Sponsor
- Complement Therapeutics
Labor; Prolonged, Second Stage, Delivery Problem
Maternal Position's Effect on Labor Progression in Occiput Posterior Deliveries
This is a randomized controlled experimental study to determine the effect of maternal position on the progression of labour in deliveries in which the foetus is in the occiput posterior position.
- Trial name
- NCT06928038
- Testing
- Positioned group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Second Stage of Labor
Searching for the Perfect Oil to Protect the Perineum: A Randomized-Controlled, Double-Blind Trial
In this study we intend to randomly assign each parturient one of two commonly used oils to be applied during the second stage of labor, one of them containing vitamin E.
- Trial name
- NCT00662974
- Testing
- perineal massage with Wheat Germ Oil during the second stage of labor, perineal massage with almond oil during the second stage of labor
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Second Stage of Labor
Caffeine in the Second Stage of Labor in Low-risk Nulliparous Mothers at Term
Single blind, randomized control trial to determine benefit of caffeine and sodium benzoate on the second stage of labor
- Trial name
- NCT05906303
- Testing
- Caffeine and Sodium Benzoate Injection, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Pregnancy
Optimizing Management of the 2nd Stage of Labor: Multicenter Randomized Trial
The investigators propose a large, multicenter, randomized clinical trial of immediate versus delayed pushing for nulliparous women in labor at term reaching complete cervical dilation.
- Trial name
- OMSS (NCT02137200)
- Testing
- Immediate pushing, Delayed pushing
- Where
- 6 sites in United States
- Volunteers
- 2,414 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Urinary Incontinence, Pelvic Organ Prolapse
Promoting Effective Recovery From Labor Urinary Incontinence (PERL)
The purpose of this study is to determine whether pushing during labor that is controlled by the woman results in less birth-related injury and less postpartum urinary incontinence (UI).
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
- Trial name
- PERL (NCT00506116)
- Testing
- Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obstetric Labor Complications, Vacuum Extraction; Failure, Affecting Fetus or Newborn
Comparison of Prevention and Appropiate Obstetric Interventions for Prolonged Second Stage Labor at Term Pregnancies During Vaginal Delivery
Randomized Control Trial for Comparison of Prevention and Appropiate Obstetric Interventions for Prolonged Second Stage Labor at Term Pregnancies During Vaginal Delivery.
- Conditions
- Obstetric Labor Complications, Vacuum Extraction; Failure, Affecting Fetus or Newborn, Complicated Labour/Delivery Livebirth
- Trial name
- NCT04888871
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Active Second Stage
Alternative to Intensive Management of the Active Phase of the Second Stage of Labor
Active phase of the second stage of labor corresponds to period of maternal expulsive efforts (i.e. pushing). An intensive management of this phase is usual in France.
- Trial name
- PASST (NCT03018860)
- Testing
- "Moderate" management, "Intensive" management
- Where
- France
- Volunteers
- 1,701 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor and Delivery
Effect of a Vertical Birthing Chair on Labor
The goal of this randomized clinical trial is to evaluate whether the use of a vertical birthing chair during the active second stage of labor improves fetal head descent and rotation.
- Trial name
- NCT07874243
- Testing
- Using a vertical birthing chair during the active second stage of labor
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Pregnancy
Use of an Occlusal Support Device During the Second Stage of Labor
The primary objectives of this study are to determine if the use of an Occlusal Support Device (OSD)(Mouthguard) can reduce the duration and intensity of the second stage of labor, reduce the incidence of labor complications…
- Trial name
- NCT02807493
- Testing
- Occlusal Support Device, Control
- Where
- United States
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Length of Labor, Second Stage of Labor
Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas
This randomized controlled trial aims to compare three groups of intravenous fluids and their impact on labor: 1) 125 mL/hr of 5% dextrose in normal saline 2) 250 mL/hr of normal saline 3) 250 mL/hr of 5% dextrose in normal saline
- Conditions
- Length of Labor, Second Stage of Labor, Intravenous Hydration of Labor
- Trial name
- NCT01904617
- Testing
- Dextrose, Normal Saline
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
The Length of Second Labor Stage in Primigravidae on Maternal & Neonatal Outcomes
Effect of the Length of Second Stage of Labor in Primigravidae on Maternal & Neonatal Outcomes
The primary purpose of this study is to compare the effects of two different methods of care during the second stage of labor for nulliparous women (coached versus uncoached pushing) on the length of the second stage and how this…
- Trial name
- RCT (NCT02676505)
- Testing
- Coached pushing group, uncoached pushing group
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Obstructed Labor at Second Stage of Labor
Reverse Breech Extraction Versus Push Technique for Fetal Delivery When Fetal Head is Deeply Impacted in the Pelvis During CS on A Fully Dilated Cervix
Management of impacted fetal head during second stage cesarean requires careful and gentle attention to various surgical steps for delivery of a fetus without adverse maternal and neonatal outcomes, mostly by an experienced…
- Trial name
- NCT05707650
- Testing
- reverse breech extraction technique or push technique
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Childbirth Experience, Urinary Retention
Analgesia in the Second Stage of Labour
This study investigates efficacy, safety and childbirth experience in women receiving pudendal block during the final stage of delivery. It is an observational study and half of included primarous women recieve a pudendal block.
- Conditions
- Childbirth Experience, Urinary Retention, Satisfaction, Personal, Pain, Obstetric
- Trial name
- ASL (NCT04391075)
- Testing
- Pudendal nerve block
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Labor Complication, Pregnancy Related
PROphylactic Manual RotatIon in the Second stagE of Labor
This is a randomized controlled trial to determine whether prophylactic manual rotation for fetuses identified to have persistent occiput posterior or occiput transverse presentation (POP/OTP) at the initiation of the second…
- Trial name
- PROMISE (NCT05175040)
- Testing
- Prophylactic manual rotation
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Labor Stage, Second
Using a Mirror in the Second Stage of Labor: Effects on Duration and Birth Experience
This study aims to investigate the impact of using a labor mirror during the second stage of labor on both the duration of labor and the mother's overall experience.
- Trial name
- NCT06648161
- Testing
- Labor Mirror
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Kocaeli University