Clinical trials: Screening Test
Plasmodium Falciparum Malaria
Mass Screening and Treatment for Reduction of Falciparum Malaria
In this project, the investigators aim at an operational research deployment of Ultrasensitive Rapid Diagnostic Test (URDT) -based Mass Screening and Treatment (MSAT) in the Malaria Elimination Task Force (METF) elimination…
- Trial name
- MSAT (NCT04093765)
- Testing
- Ultrasensitive Rapid Diagnostic Test (URDT), Antimalarials
- Where
- Thailand
- Volunteers
- 5,542 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Colorectal Cancer
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
The primary objective is to confirm the specificity of a multi-target stool DNA test (mt-sDNA), Cologuard, in an average risk population, ages 45-49.
- Trial name
- NCT03728348
- Testing
- mt-sDNA screening test, Colonoscopy
- Where
- 39 sites in United States
- Volunteers
- 983 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Cancer, Colorectal Neoplasms
Effect of Patient Portal Messaging Before Mailing Fecal Immunochemical Testing Kit on Colorectal Cancer Screening Rates
Behavioral economics principles have increasingly been shown to improve health outcomes in the United States. They offer the ability to implement simple, low-cost and effective interventions to address key health issues without…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Cancer Screening
- Trial name
- NCT05115916
- Testing
- MyChart Priming Message
- Where
- United States
- Volunteers
- 3,880 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hearing Loss
Validation Of Cambodia Version of Five Minutes Hearing Test
Seek the simple tool as questionnaire for screening hearing loss. The FMHT was developed by American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). It is a standard hearing questionnaire.
- Trial name
- CAM-FMHT (NCT05736055)
- Testing
- Cambodia Version Five Minutes Hearing Test
- Where
- Cambodia
- Volunteers
- 481 people
- Sponsor
- Khon Kaen University
Cervical Cancer, Intraepithelial Neoplasia
Cervical And Self-Sample In Screening Study
The proposed study seeks to compare the diagnostic performance of Human Papillomavirus (HPV) testing in self-collected samples via the Eve Medical self-collection system© (Eve) with standard physician-collected samples for the…
- Trial name
- CASSIS (NCT02397252)
- Testing
- Eve Medical self-collection system©, cobas® PCR Female swab self-sampling, Physician-collected sampling
- Where
- Canada
- Volunteers
- 1,225 people, healthy volunteers welcome
- Sponsor
- McGill University
Colon Cancer Screening
A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
The Black community has higher rates of colorectal cancer and lower rates of colorectal cancer screenings than whites. Getting screened through FIT testing may help catch colorectal cancer earlier, when it is easier to treat.
- Trial name
- NCT05793593
- Testing
- FITx3 intervention and CRC education, Colorectal Cancer (CRC) education alone
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Aneuploidy
A Pilot Study for Implementation of First Trimester Screening of Aneuploidies in Campania Region
The study aims to compare two different protocols for first trimester screening of aneuploidies, one based on nuchal translucency and NIPT and another one based on the integration between combined test and NIPT, in order to…
- Trial name
- PISTA (NCT05798858)
- Testing
- NIPT
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hypercholesterolemia, Familial
Is Family Screening Improved by Genetic Testing of Familial Hypercholesterolemia
To test the hypothesis that in patients with a clinical diagnosis of familial hypercholesterolemia (FH), genetic testing and identification of a causative mutation might enhance the success of family-based cascade screening.
- Trial name
- IFIGhTFH (NCT04526457)
- Testing
- Standard of Care, Genetic Testing
- Volunteers
- 240 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Use of an Ultra-rapid BRCA1/2 Status Screening Test in Diagnostic and Theranostic Indication: Performance and Interest for Patients and Practitioners
The time taken to obtain the results of germline mutations in BRCA1 and BRCA2 has become a major issue in adapting the therapeutic management of patients, particularly those with breast cancer.
- Trial name
- TURBO (NCT06111417)
- Testing
- Questionnaires, Communication of the results of the BRCA1/2 ultra rapid test
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Georges Francois Leclerc
Infective Endocarditis (IE), Heart Valve Disease
The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.
This randomized, multicenter, open-label trial evaluates whether preoperative dental screening improves outcomes in patients undergoing surgical or transcatheter cardiac valve intervention.
- Trial name
- SMILE (NCT07511673)
- Testing
- Preoperative dental screening, No preoperative dental screening
- Where
- 5 sites in Sweden
- Volunteers
- 1,300 people
- Sponsor
- Region Skane
Colorectal Cancer, Adenoma Colon
Effectiveness of Multi-target FIT-DNA Analysis as a Colorectal Cancer Screening Test
Colorectal cancer is one of the most common cancer in Hong Kong. In 2018, CRC accounted for 17.4%, 5,780 cases, of the total new cancers. CRC claimed 2,279 lives (15.8%) making it the second most deadly killer in the population.
- Trial name
- NCT04194879
- Testing
- multi-target FIT-DNA analysis
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Hodgkin Lymphoma
A Survey Exploring Health and Screening Tests in People Treated for Hodgkin Lymphoma
A survey of health beliefs and cancer screening behaviour and intentions in Hodgkin lymphoma survivors
- Trial name
- NCT04996862
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- The Christie NHS Foundation Trust
Malaria, Pregnancy
Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy
The incidence of malaria, including the incidence in pregnant women, is declining in many African countries. Thus, there is a need to re-examine the efficacy and cost effectiveness of giving intermittent preventive treatment with…
- Conditions
- Malaria, Pregnancy, Anaemia
- Trial name
- IPTp_IST (NCT01084213)
- Testing
- Intermittent screening and treatment of malaria in pregnancy (IST), SP-IPTp
- Where
- 4 sites in Burkina Faso, Ghana and 2 more
- Volunteers
- 5,354 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Colorectal Cancer
Evidence-Based Colorectal Cancer Screening for the Uninsured
Through this program, the investigators will test a systematic colon cancer screening outreach strategy for increasing screening completion among uninsured patients, not up-to-date with screening.
- Trial name
- NCT01946282
- Testing
- FIT Invitation Only, FIT plus $5 Incentive, FIT plus $10 Incentive
- Volunteers
- 8,565 people
- Sponsor
- University of Texas Southwestern Medical Center
Reading Disability, Dyslexia
Eye Movements and Reading Disabilities
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment…
- Trial name
- EOMRD (NCT01860027)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Scripps Health
HIV Infections, ART
Evaluation of Secondary Distribution of HIV Self-screening Tests by Women With HIV
Many South African men do not visit clinics or get tested due to multiple real and perceived barriers. Nkangala District has significant gaps to identifying PLHIV who are not on ART, reaching their ART targets, especially in…
- Conditions
- HIV Infections, ART, HIV Seropositivity
- Trial name
- HIVSSSA (NCT05074251)
- Testing
- HIV self test, Counseling and referral for partner testing
- Where
- South Africa
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Colorectal Cancer
Testing Interventions to Motivate and Educate
This study is being done to see if teaching physicians and people who are at least 50 years old and have not been screened within guidelines for colorectal cancer about the importance of colorectal cancer screening will increase…
- Trial name
- TIME (NCT01568151)
- Testing
- Clinic-directed intervention program, Individual Patient-Directed Program
- Where
- United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer, Colon Polyp
Colorectal Cancer Screening Using Stool DNA-based SDC2 Methylation Test
A study of colorectal cancer screening using stool DNA-based SDC2 methylation test
- Conditions
- Colorectal Cancer, Colon Polyp, Healthy
- Trial name
- NCT04304131
- Testing
- Earlytect Colon Cancer
- Where
- 8 sites in South Korea
- Volunteers
- 1,210 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Cervical Precancer
Development, Field Testing and Evaluation of the Efficacy of a Hand-held, Portable and Affordable Thermo-coagulator to Prevent Cervical Cancer in Low- and Middle-income Countries
This project develops, tests and produces a lightweight, cordless, battery driven and rechargeable hand-held device for treating cervical precancer (Liger Thermal Coagulator).
- Trial name
- DELTA (NCT02956239)
- Testing
- Thermocoagulation (device), Cryotherapy (device), LEEP (device)
- Where
- Zambia
- Volunteers
- 3,124 people
- Sponsor
- International Agency for Research on Cancer
Breast Cancer, Liquid Biopsy, Early Detection
Clinical Validation of Early Detection Blood Test for Universal Large-scale Breast Cancer Screening
Breast cancer is the most common cancer that spreads beyond the initial layer of tissue it developed in, and grows into surrounding healthy tissue in women worldwide. It is associated with significant illness and death.
- Trial name
- NCT07219277
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Syantra Inc.