Clinical trials: Scleral Contact Lenses
Scleral Lens Wearers
Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular Refractive Errors Compared to Habitually Worn Scleral Lenses
This study will be done with subjects who already habitually wear scleral contact lenses. The study lens is made with a material that is already widely available and has a new design.
- Trial name
- NCT02643095
- Testing
- scleral contact lens
- Volunteers
- 22 people
- Sponsor
- Jennifer Fogt
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Keratoconus, Healthy Controls
Corneal Thickness Changes With Scleral Contact Lenses
The purpose of this study is to investigate changes in the corneal thickness of scleral contact lens wearers in a keratoconic (KC) population and compare to age-matched controls.
- Trial name
- NCT03249233
- Testing
- ZenLens™, Zen™ RC
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Keratoconus
Changes in the Tear Film With Scleral Contact Lens Wear for Keratoconic Eyes
The purpose of this study is to investigate changes in the level of inflammatory mediators in the tear film of scleral contact lens wearers in a keratoconic population.
- Trial name
- NCT02806921
- Testing
- ZenLens
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Keratoconus, Presbyopia
Proof-of-Concept for a Novel Optical Aperture Contact Lens in Presbyopia and Keratoconus
The purpose of this clinical study is to evaluate the effectiveness of the NOA lens, a custom-made scleral contact lens developed by Azalea Vision BV, in improving visual quality for individuals with keratoconus and presbyopia.
- Conditions
- Keratoconus, Presbyopia, Scleral Contact Lenses, Pinhole
- Trial name
- NOA (NCT07559188)
- Testing
- NOA lens type 1, NOA lens type 2
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Azalea Vision
Dry Eye, Dry Eye Syndromes
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Tangible Hydra-PEG is a novel coating technology designed to improve lens wettability, deposit resistance, and tear film breakup time.
- Trial name
- NCT03417505
- Testing
- Scleral lenses treated with Tangible Hydra-PEG, Untreated scleral lenses
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Tangible Science
Irregular; Contour of Cornea, Keratoconus
Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
The most common causes for irregular cornea (IC) in hospital contact lens practice are Keratoconus (KC) and related cornea thinning disorders.
- Conditions
- Irregular; Contour of Cornea, Keratoconus, Pellucid Marginal Corneal Degeneration, Injury of Cornea
- Trial name
- NCT02444923
- Testing
- Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™), Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London South Bank University
Scleral Contact Lenses
Effect of Ocular Hygiene on Scleral Lens Wear
This is a study to evaluate the performance of Lid Scrubs when added to the daily regimen of scleral lens wear. Lid Scrubs contain surfactants and chemically developed Ringer's solution with microbial attributes.
- Trial name
- NCT03544385
- Testing
- Ringers Solution
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Houston
Irregular; Contour of Cornea
Scleral Contact Lens Insertion Solution Study
The purpose of this study is to determine the clinical ocular compatibility (feasibility of safety and efficacy) of a patented solution (US Patent 2,259,437, Stone) which contains multiple essential ions and has a pH and tonicity…
- Trial name
- NCT03612284
- Testing
- contact lens insertion solution
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jennifer Fogt
Contact Lens Complication, Debris in Post Lens Tear Reservoir
Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging
Evaluation of saline solutions used with scleral rigid gas permeable contact lens wearers experiencing debris in the post lens tear reservoir
- Trial name
- NCT03525704
- Testing
- Saline Solution Enriched, Saline Rinse Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Keratoconus
Impact of Scleral Contact Lens Wear on Corneal Nerves in Keratoconus
The purpose of this study is to investigate changes in corneal innervation during scleral contact lens wear in a keratoconic population.
- Trial name
- NCT03091101
- Testing
- Scleral lens wearing keratoconics
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Low Vision
Performance of Rigid Gas Permeable (RGP) Scleral Contact Lenses With a Passive Artificial Iris
Data from 15 healthy subjects will be recorded in two testing sessions spread on two days, using three lens designs (A, B and C).
- Trial name
- RGPIRIS_PA (NCT04040790)
- Testing
- Scleral contact lens without a passive artificial iris, Scleral contact lens with a passive artificial iris with low contrast (<1:5), Scleral contact lens with a passive artificial iris with high contrast (>1:5)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Ghent
Keratoconus, Irregular Astigmatism
Effect of Corneal and Scleral RGP Lenses on Ocular Health and Visual Quality in Keratoconus
This study aims to compare the ocular health and visual quality of corneal rigid gas permeable lenses (CRGPL) and scleral rigid gas permeable lenses (SRGPL) for patients with keratoconus in a crossover clinical trial.
- Trial name
- NCT06921967
- Testing
- Rose K2, Onefit MED
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Contact Lens Adaptation
Maximizing the Initial Experience of a Neophyte Scleral Lens Wearer
The goal of this proposal is to conduct a randomized controlled study aimed at learning the best method for applying scleral lenses and factors associated with successfully completing scleral lens application and removal training.
- Trial name
- NCT04583579
- Testing
- DMV inserter (DMV® MagicTouch™) with an open end, DMV inserter (DMV® MagicTouch™) with a closed end, Three fingers (Patient's Hand)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Alabama at Birmingham
High Myopia
A Study on the Efficacy and Safety of Multi-focal Scleral Contact Lens
The rigid scleral contact lens with optical multi-focal design adopted in this study can focus the light in part of the optical area on the front of the retina to form myopic defocus, in order to delay the axial changes in…
- Trial name
- NCT05533450
- Testing
- Multi-focal rigid scleral contact lens, Rigid gas permeable contact lens
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center