Clinical trials: Sciatic Nerve
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pain
A Novel Concept for Continuous Peripheral Nerve Block - Sciatic Nerve
To investigate the function of a novel catheter for continuous peripheral nerve blocks in the popliteal nerve: Two key issues are investigated 1) Successful primary placement and function of the catheter for continuous peripheral…
- Trial name
- NCT02456597
- Testing
- lidocainhydrochlorid, Isotonic Saline
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kai Henrik Wiborg Lange
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Piriformis Syndrome
Muscle Energy Technique and Stretching Exercise in Working Pregnant Women With Piriformis Syndrome
Piriformis syndrome is a neuro muscular disorder which occur due to the compression and irritation of the sciatic nerve by the piriformis muscle causing pain, tingling, and numbness in the buttocks and along the sciatic nerve.
- Trial name
- NCT05915858
- Testing
- muscle energy technique, stretching exercise
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hallux Valgus, Surgery
Continuous Versus Automated Bolus Infusion in Sciatic Nerve Catheters
This study is developed to determine if the local anaesthetic dose can be reduced by the use of intermittent bolus technique compared to continuous infusion when the nerve catheter is placed underneath the paraneurium by…
- Trial name
- NCT02293330
- Testing
- continuous infusion of levobupivacaine, Intermittent bolus infusion of levobupivacaine
- Where
- Belgium
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Piriformis Muscle Syndrome, Anthropometry
Pelvic and Hip Morphometry in Piriformis Syndrome
In this case-control study, 23 patients diagnosed as PS by diagnostic injection with ultrasound guidance were selected as the study group.
- Trial name
- NCT04600024
- Testing
- Ultrasound guided diagnostic injection
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Piriformis Syndrome
Soft Tissue Techniques in Piriformis Syndrome
The purpose of the study is to compare the effects of active release technique and post isometric relaxation in patients with piriformis syndrome on pain, hip internal rotation range of motion and functional disability.
- Trial name
- NCT04842656
- Testing
- Post isometric relaxation, Active release technique alongwith conventional treatment
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Relatively Healthy Volunteers
Optimizing Local Anesthetic Concentration for Continuous Popliteal-Sciatic Nerve Blocks
A continuous peripheral nerve block-also termed "perineural local anesthetic infusion"-involves the insertion of a tiny tube (a "catheter") through the skin and adjacent to a peripheral nerve, followed by local anesthetic…
- Trial name
- NCT01898689
- Testing
- Ropivacaine 0.1%, Ropivacaine 0.4%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Piriformis Syndrome
Effects of Neural Mobilization and Stretching in Piriformis Syndrome
This study compares the effects of piriformis stretching and neural mobilization of the sciatic nerve in individuals with piriformis syndrome, a condition that is frequently characterized by hip and buttock pain and discomfort…
- Trial name
- NCT06808659
- Testing
- Neural Mobilization, Stretching
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bahria University
Knee Injuries
Femoral/Sciatic Block for Knee Surgery
Knee arthroplasty has a high potential for postoperative pain. This study compares analgesia and postoperative bleeding from intrathecal morphine with the continuous femoral and a single-shot sciatic nerve blockades.
- Trial name
- NCT02882152
- Testing
- femoral nerve blockade, morphine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Total Knee Arthroplasty
Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic…
- Trial name
- NCT02223364
- Testing
- Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postoperative Pain
Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA
The aim of this study was to observe the effects of posterior femoral cutaneous nerve block combined with sciatic and saphenous nerve block compared with sciatic and saphenous nerve block alone on postoperative posterior side of…
- Trial name
- NCT06522620
- Testing
- Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block, Simple Sciatic and Saphenous Nerve Blocks
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Piriformis Syndrome
Effects of Soft Tissue Mobilization Technique and Piriformis Muscle Stretching Among Patients Having Piriformis Syndrome
It is a randomized control trail in which soft tissue mobilization and piriformis stretching will be compared and study duration will be of five months
- Trial name
- NCT05680402
- Testing
- Soft Tissue mobilization, Piriformis Syndrome (Piriformis muscle stretching)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Healthy
The Application of Neuromodulation in Sciatic Nerve
The objective of this study will be to analyze the muscle activity of the short head (SHBF) and long head of the biceps femoris (LHBF) after the application of ultrasound-guided percutaneous neuromodulation (NMP) in the tibial or…
- Trial name
- NCT05549700
- Testing
- Neuromodulation
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Seville
Healthy, Nerve Block
Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region
This is a national, single-center, dose-escalation Phase I study to investigate the safety, pharmacokinetics, and efficacy of a combination containing Ropivacaine, Clonidine, and Betamethasone (Ropiclobet) in healty volunteers.
- Trial name
- RopiCloBet (NCT06781632)
- Testing
- ropivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- PHARMAFINA
Sciatica Pain, Sciatica Acute
SNAG and SNME in Non-Specific Sciatic Pain
This study is designed as a crossover trial. All participants who meet the inclusion criteria and voluntarily agree to participate will be evaluated using the assessment methods detailed below.
- Conditions
- Sciatica Pain, Sciatica Acute, Mulligan Mobilization
- Trial name
- CASE-SNAG (NCT07161323)
- Testing
- Sustained Natural Apophyseal Glide (SNAG), Sciatic Nerve Mobilization Exercises (SNME)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istinye University
Popliteal Sciatic Nerve Block
Comparing Classical Approach and Crosswise Approach to Popliteal Sciatic Nerve Block
Sensory and motor innervation below the knee is provided mainly by the popliteal-sciatic nerve except for a variable area of the medial leg supplied by the saphenous nerve.
- Trial name
- NCT07134608
- Testing
- Popliteal Plexus Block with 20 ml
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Sciatic Nerve
Sciatic Nerve Stiffness Using Two-Sequences of Lower Limb Neurodynamic Testing: A Shear Wave Elastography Study
The purposes of the study are: 1. To measure differences in Sciatic nerve (SN) stiffness using shear-wave elastography (SWE) during two movement sequences of the lower limb neurodynamic test (LLNT) in low back pain with sciatica.
- Trial name
- NCT07136441
- Testing
- Lower Limb Neurodynamic Test (LLNT) with Shear Wave Elastography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University