Clinical trials: Schistocytes
Drepanocytosis
Study of a Deformability Parameter of Red Blood Cell
Sickle-cell disease is one of the most common severe monogenic disorders in the world, it results in the synthesis of abnormal hemoglobin (HbS) instead of hemoglobin A.
- Trial name
- FITRED (NCT05850156)
- Testing
- basal blood collection, blood collection M6, blood collection M12
- Volunteers
- 130 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Sickle Cell Disease, Infant, Newborn, Disease
DREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry
Three methods are actually used in newborn screening for sickle cell disease (SCD) in France: isoelectric focusing, high performance liquid chromatography and capillary electrophoresis.
- Conditions
- Sickle Cell Disease, Infant, Newborn, Disease, Drepanocytosis
- Trial name
- DREPAMASSE (NCT03985501)
- Testing
- SCD newborn screening with the MS/MS method from Zentech
- Where
- 3 sites in France
- Volunteers
- 1,431 people
- Sponsor
- Hospices Civils de Lyon
Sickle Cell Disease, Drepanocytosis
Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.
Sickle cell disease (SCD) is an inherited blood disorder. Symptoms include acute and chronic complications. Due to progress in SCD care, patients with SCD are living longer than before and we focus more attention in chronic…
- Trial name
- Drépa-COG (NCT04244240)
- Testing
- BEARNI Tool
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Hospices Civils de Lyon
Red Blood Cells, Schistocytes
ERYthrocyte Morphology Using Flow Imaging on ImageSTREAM Cytometer
Erythrocyte morphology analysis is a key step in the diagnosis flowchart of anemia. It is performed on a peripheral blood smear after May Grümwald Giemsa staining.
- Conditions
- Red Blood Cells, Schistocytes, Artificial Intelligence
- Trial name
- ERYSTREAM (NCT05282888)
- Testing
- blood sample
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pre-Eclampsia, Severe, HELLP Syndrome
Promising Bimarker Prediction of Outcome of HELLP Syndrome.
HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia.
- Conditions
- Pre-Eclampsia, Severe, HELLP Syndrome, Microangiopathy
- Trial name
- NCT03246542
- Testing
- shistocytes percentage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AYMAN ABDELKADER MOHAMED ABDELKADER
Cardiogenic Shock, Malignant Arrhythmias
The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martinique
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing VV, VA or VAV ECMO implantation in the French West Indies and Guiana.
- Conditions
- Cardiogenic Shock, Malignant Arrhythmias, Ischemic or Valvular Heart Failure, Drepanocytosis and Thoracic Syndrome
- Trial name
- NCT07351435
- Volunteers
- 1,200 people
- Sponsor
- University of Genova
Drepanocytosis, Chronic Neurological Deficiency
Transfusion Exchanges and Cognition in Sickle Cell Disease
DREPA-COG is an observational study evaluating the effect of exchange transfusions on cognitive function in adults with severe sickle cell disease (SS or Sβ0).
- Trial name
- DREPA-COG (NCT07168447)
- Where
- 6 sites in France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier St Anne
Leukemia, Myeloid, Acute, Leukemia, B-cell
Precision Exercise in Children With Malignant Hemopathies
In the early years of life and during adolescence, physical activity is crucial for good development of motor skills. It is even more so for those children and young people who are forced to undergo anti-cancer therapies and…
- Conditions
- Leukemia, Myeloid, Acute, Leukemia, B-cell, Leukemia, T Cell, Lymphoma, Hodgkin
- Trial name
- SportTherapy (NCT04090268)
- Testing
- Sport Therapy
- Where
- Italy
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
SNAKEBITE, THROMBOTIC MICROANGIOPATHY
Incidence of Snakebite Associated Thrombotic Microangiopathy & Role of Peripheral Blood Smear as a Predictor of Clinical Outcome
The aim of this study is to find the overall incidence of thrombotic microangiopathy in snakebite victims. As we know snakebite is a common in tropical regions.
- Conditions
- SNAKEBITE, THROMBOTIC MICROANGIOPATHY, SCHISTOCYTES
- Trial name
- NCT04845022
- Where
- India
- Volunteers
- 81 people
- Sponsor
- Jubilee Mission Medical College and Research Institute