Clinical trials: Scars
Scar
Fractional Photothermolysis for the Treatment of Burn Scars
The aim of our study is to determine the effect of fractional photothermolysis laser in the treatment of burn scars.
- Trial name
- NCT01005992
- Testing
- Fractional laser treatment, Standard scar management
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Clinica las Condes, Chile
Adhesions, Hand Fractures
Lipofilling in Operative Hand Fracture Treatment
Background: Hand fractures are a common clinical problem worldwide and account for a substantial economic burden and workload for experienced hand surgeons.
- Conditions
- Adhesions, Hand Fractures, Tenolysis
- Trial name
- NCT07815444
- Testing
- Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Ileostomy - Stoma, Inflammatory Bowel Diseases
Stoma Closure and Reinforcement Trial ll
Hernia formation at sites of ostomy closure is a common complication. The investigator believes that using evidence based hernia repair techniques as a preventive measure during closure of ostomies will reduce the incidence of…
- Trial name
- SCAR-ll (NCT04916067)
- Testing
- Mesh Implantation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Scars, Keloids
Silicone vs Pirfenidone in the Treatment of Hypertrophic Scars and Keloids
Justification: Keloid scars are a major medical and cosmetic problem, especially in darker skin types that predominate in Mexico. It is estimated that hypertrophic scars affecting from 1.5 to 4.5% of the general population.
- Conditions
- Scars, Keloids, Hypertrophic Scar
- Trial name
- NCT06909812
- Testing
- pirfenidone 8% gel, silicon gel
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
Burn, Hypertrophic Scar
Intron A for the Treatment of Hypertrophic Scar
This study assesses the intervention with antifibrotic agents, specifically interferon (IFN) to reduce the magnitude and duration of hypertrophic scar.
- Trial name
- NCT00686478
- Testing
- interferon alpha 2b
- Where
- Canada
- Sponsor
- University of Alberta
Acne Vulgaris
Treatment of Acne Vulgaris Using NAFL in Combination With Isotretinoin and Pricking Blood Therapy
BACKGROUND Isotretinoin remains one of the first line medications for moderate-to-severe acne vulgaris (AV) but its side effect is a major concern for Asian patients.
- Trial name
- NCT04156815
- Testing
- 1,565nm NAFL, Oral isotretinoin, Pricking blood therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- xjpfW
Adhesion
Efficacy and Dose Ranging Study of Seroguard
This trial was a multi-center, double-blind, randomized, parallel group, placebo-controlled, phase II study in adult hospitalized female patients with the confirmed diagnosis of pelvic adhesive disease in Study centres in Russia.
- Trial name
- NCT03660787
- Testing
- Seroguard
- Where
- 14 sites in Russia
- Volunteers
- 114 people
- Sponsor
- Pharmasyntez
Myocardial Infarction
Characterization of Myocardial Infarction Scar Using Magnetic Resonance Imaging
The goal of this monocentric observationnal study is to describe the characteristics of the myocardial infarction scar in terms of transmurality in residual LVEF>35% patients.
- Trial name
- MI-SCAR-MRI (NCT05967026)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Acne Scars - Mixed Atrophic and Hypertrophic
Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring
To evaluate the efficacy of a tripeptide/hexapeptide topical (Alastin Regenerating Skin Nectar with TriHex Technology®) in wound healing and scar reduction following Erbium:YAG hybrid resurfacing laser for acne scarring compared…
- Trial name
- NCT04606134
- Testing
- Hybrid fractional laser, Alastin Regenerating Skin Nectar with TriHex Technology, Cetaphil face cream
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Cesarean Section Complications, Scar Niche
Uterine Scar Resection During Repeat Cesarean Delivery to Prevent Uterine Niche Formation
The purpose of the study is to evaluate whether resection of the previous cesarean scar at repeat cesarean delivery reduces uterine niche formation and related morbidity without increasing operative risks.
- Conditions
- Cesarean Section Complications, Scar Niche, Scarred Uterus
- Trial name
- NCT07228858
- Testing
- Repeated cesarean section with previous uterine cesarean section scar resection, Repeated cesarean section without uterine scar resection, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Benha University
Meningioma
3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features
This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma…
- Trial name
- NCT06955208
- Testing
- Magnetic Resonance Elastography, Intraoperative Assessment and Recording
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Scar
Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of early postoperative skin surface reduction in improving scar formation after facial surgery.
- Trial name
- NCT03842644
- Testing
- Tension reduction device
- Where
- China
- Volunteers
- 55 people
- Sponsor
- XiaoXi Lin
Ovarian Cancer, Epithelial Ovarian Cancer
A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)
The purpose of this study is to determine which patients with ovarian, fallopian tube, and primary peritoneal cancer will best respond to treatment with rucaparib.
- Conditions
- Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- ARIEL2 (NCT01891344)
- Testing
- Oral rucaparib
- Where
- 75 sites in United States, Australia and 4 more
- Volunteers
- 491 people
- Sponsor
- pharmaand GmbH
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D
Cesarean Section; Infection, Scar
Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision
Our primary aim is to determine the most beneficial suture in order to reduce complications due to skin incision in common surgeries such as cesarean section, and our secondary aim is to evaluate the suture material used in terms…
- Trial name
- NCT06119113
- Testing
- Evaluation of the wound infection at the 10th day post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 6th month post-op check-up among all groups
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ayşenur Çalış Özbayram
Surgical Wounds, Mohs Surgery
The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery.
- Trial name
- NCT07583862
- Testing
- Topical Timolol, Normal Saline
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Geisinger Clinic
Adhesion
PMCF Study for COSEAL® in Gynecologic Surgery
The study is a single-arm, retrospective, chart review with a patient questionnaire intended to supplement the patient chart, when necessary.
- Trial name
- NCT05996809
- Testing
- Coseal
- Where
- 2 sites in United States, Italy
- Volunteers
- 200 people
- Sponsor
- Baxter Healthcare Corporation
Skin Regrafting; Donor Site of Skin Grafting; Vancouver Scar Scale
Management of Skin Graft Donor Site Wound in Aged Patient
The complication of donor site in skin grafting often acts as a causing factor for extended treatment period. The elderly individuals tend to be afflicted by impaired wound healing.
- Trial name
- NCT05371171
- Testing
- skin graft, no skin graft
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Taipei Medical University WanFang Hospital
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