Clinical trials: Scabies
Scabies
Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)
The ETSKABI study is a prospective, open-label, multicenter, initially single-armed and in case of treatment failure subsequently three-armed randomized clinical trial.
- Trial name
- ETSKABI (NCT04814511)
- Testing
- InfectoScab 5 % Creme, Permethrin 10 % Creme, Driponin 3 mg Tabletten
- Where
- 8 sites in Germany
- Volunteers
- 183 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Scabies
A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies
To determine and compare the safety and efficacy of permethrin foam 4% and permethrin foam 5% with that of vehicle in subjects with scabies.
- Trial name
- NCT02094716
- Testing
- Permethrin Foam 4%, Permethrin Foam 5%, Vehicle Foam
- Where
- 9 sites in United States, Dominican Republic and 2 more
- Volunteers
- 130 people
- Sponsor
- Mylan Inc.
Scabies
Efficacy and Side Effects of Blacksoap® as Adjuvant Therapy of Scabies
Background: Scabies is a skin disease due to Sarcoptes scabiei. The transmission risk is high among communities living together, such as dormitories, boarding schools, nursing homes, and so on.
- Trial name
- NCT05025696
- Testing
- Blacksoap(R)
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Indonesia
Scabies
HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation
This is a clinical trial to compare two formulations of the drug ivermectin: the standard 3mg tablet formulation versus a newly developed infant formula preparation.
- Trial name
- HEALTH (NCT06918665)
- Testing
- ivermectin infant formula preparation, Standard ivermectin 3mg tablet
- Where
- Australia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Scabies
Efficacy and Safety Study of Moxidectin in Adults With Scabies
Moxidectin is not approved to treat scabies in humans. The effective dose of moxidectin to treat scabies is not known. This study aims to assess the efficacy of a single administration of 8 mg, 16 mg, or 32 mg moxidectin per oral…
- Trial name
- NCT05875441
- Testing
- Moxidectin Oral Product
- Where
- 9 sites in United States, Dominican Republic and 2 more
- Volunteers
- 200 people
- Sponsor
- Medicines Development for Global Health
Scabies
Comparison of Permethrin-Based Treatment Strategies Against Scabies in Infants and Young Children
To compare the efficacy of different permethrin-based therapies for scabies infestations in infants and young children.
- Trial name
- NCT07247630
- Testing
- Permethrin 5%
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Streptococcus Group A
Streptococcal Infections in Fiji - Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji
Group A streptococcus (GAS) is a bacteria that causes many different sicknesses in children and adults. This study will look at the number of cases of pyoderma (bacterial skin infection) and scabies (skin mites that cause…
- Trial name
- NCT00436891
- Where
- Fiji
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Scabies
Comparison of the Efficacy and Safety of Ivermectin to Permethrin
Comparison of the efficacy and safety of a single administration of ivermectin to a single administration of permethrin for the treatment of scabies
- Trial name
- NCT00262418
- Testing
- Administration of ivermectin or permethrin
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University Ghent
Scabies, Yaws
Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
This is an open-label prospective community intervention trial to assess the impact of community mass treatment with azithromycin for yaws and ivermectin for scabies, on non-yaws bacterial skin infections.
- Conditions
- Scabies, Yaws, Impetigo
- Trial name
- AIM-Skin (NCT02775617)
- Testing
- Ivermectin, Azithromycin, Permethrin
- Where
- Solomon Islands
- Volunteers
- 1,291 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Scabies
A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies
Scabies is an infestation of the skin by the human itch mite (Sarcoptes scabiei). Diagnosis of scabies is made based on clinical symptoms, such as nocturnal itching, and appearance and distribution of the rash.
- Trial name
- NCT02572986
- Testing
- Permethrin
- Where
- 13 sites in United States, El Salvador and 1 more
- Volunteers
- 250 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Streptococcus Group A
Prevalence of RHD, Pyoderma and Scabies in Children in Fiji
The purpose of this study is to estimate the number of cases of rheumatic heart disease, pyoderma, and scabies in school age children in Fiji.
- Trial name
- NCT00284843
- Where
- Fiji
- Volunteers
- 5,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Scabies
Evaluating Pediatric Ivermectin in Children Under 15 kg (EPIC-15)
The EPIC-15 trial will evaluate the safety, pharmacokinetics, acceptability, and efficacy of pediatric ivermectin (CHILD-IVITAB) in scabies infected children weighing 5 to less than 15 kg.
- Trial name
- EPIC-15 (NCT06404333)
- Testing
- CHILD-IVITAB
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- University of Oxford
Scabies, Impetigo
Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern Territory
The purpose of this study is to determine whether a coordinated regional approach to healthy skin programs in six remote Aboriginal communities can demonstrate, not only a reduction in the burden of scabies and streptococcal skin…
- Conditions
- Scabies, Impetigo, Pyoderma, Streptococcal Infections
- Trial name
- EAHSP (NCT00884728)
- Where
- Australia
- Volunteers
- 2,329 people
- Sponsor
- Menzies School of Health Research
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Lymphatic Filariases, Scabies
Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
Lymphatic Filariasis (LF), scabies and soil transmitted helminths (STH) are common neglected tropical diseases affecting the people of Fiji.
- Conditions
- Lymphatic Filariases, Scabies, Impetigo, Soil Transmitted Helminths
- Trial name
- FIT (NCT03177993)
- Testing
- 3 drug dose - IDA, 3 drug dose - IDA with second dose of ivermectin, 2 drug dose - DA
- Where
- Fiji
- Volunteers
- 4,773 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Lymphatic Filariasis, Scabies
Better Options for Lymphatic Filariasis Treatment
The goal of this clinical trial is to learn if mass drug administration with moxidectin in combination with diethylcarbamazine, and albendazole (MoxDA) can treat lymphatic filariasis, scabies and strongyloidiasis in children and…
- Conditions
- Lymphatic Filariasis, Scabies, Strongyloidiasis
- Trial name
- BOLT (NCT07159373)
- Testing
- MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole
- Where
- Fiji
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Scabies
Veron Scabies Education and Eradication Program
The purpose of this project is to develop a community scabies eradication and education program for the highly endemic areas surrounding the Veron community on the eastern tip of the Dominican Republic.
- Trial name
- VSEEP (NCT00604084)
- Testing
- Ivermectin, Permethrin 5% lotion
- Where
- Dominican Republic
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Trachoma, Yaws
Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )
This is a cluster randomised trial evaluating the safety of co-administering Azithromycin alongside the new IDA (Ivermectin, Diethylcarbamazine, Albendazole) combination treatment for LF.
- Conditions
- Trachoma, Yaws, Lymphatic Filariases, Scabies
- Trial name
- NCT03676140
- Testing
- Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1
- Where
- Papua New Guinea
- Volunteers
- 20,000 people
- Sponsor
- Lihir Medical Centre
Scabies
Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies
Study to Evaluate the Therapeutic Equivalence of Permethrin Cream 5%in the Treatment of Scabies.
- Trial name
- NCT03178942
- Testing
- Permethrin Cream, 5%, Elimite™ Cream (permethrin) 5%
- Where
- 15 sites in United States, El Salvador and 1 more
- Volunteers
- 254 people
- Sponsor
- Encube Ethicals Pvt. Ltd.
Scabies, Head Lice
Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands
This is a pilot study evaluating if treatment for scabies also treats headlice in the same community
- Trial name
- NCT03236168
- Testing
- Ivermectin, Permethrin 5%
- Where
- Solomon Islands
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine