Clinical trials: Sarcopenic Obesity
Sarcopenic Obesity
Dissecting the Molecular and Cellular Pathophysiology of Sarcopenic Obesity in the Elderly
Ageing is characterised by a change in body composition with a parallel decrease in muscle mass and an increase and central redistribution of fat.
- Trial name
- NCT06320158
- Testing
- clinical evaluation of sarcopenic obesity
- Where
- Italy
- Volunteers
- 1,108 people
- Sponsor
- IRCCS San Raffaele
Diabetes, Obesity & Overweight
Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine Diseases
Prospective, observational, single-center, study evaluating the prevalence of sarcopenia / sarcopenic obesity in individuals with metabolic and / or endocrine diseases, as well as the potential role of myokines as biomarkers or…
- Conditions
- Diabetes, Obesity & Overweight, Cushing Syndrome, Metabolic Diseases
- Trial name
- SARC-ENDO (NCT07703683)
- Testing
- GLP-1 Receptor Agonists
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Sarcopenic Obesity
Low Calorie Diet or VLCKD Combined With Physical Training for Preserving Muscle Mass During Weight Loss in Sarcopenic Obesity
The prevalence of sarcopenic obesity (SO) is increasing worldwide, posing important challenges to public health and national health care system, especially during the COVID pandemic.
- Trial name
- NCT05287659
- Testing
- meal replacements or supplementation with leucine
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Sarcopenia, Body Composition
CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease
Supervised exercise therapy (SET) is the recommended first treatment for patients with leg artery disease (peripheral arterial disease, PAD) causing pain when walking.
- Conditions
- Sarcopenia, Body Composition, Sarcopenic Obesity, Peripheral Arterial Disease
- Trial name
- COMPOSE-PAD (NCT07433309)
- Testing
- SET physiotherapy, CT scan
- Volunteers
- 128 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Retroperitoneal Sarcoma, Body Composition
Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma
This is a retrospective, observational study in consecutive patients operated on for primary RPS in the Institute of Oncology Ljubljana (Slovenia) between September 1999 and June 2020.
- Conditions
- Retroperitoneal Sarcoma, Body Composition, Malnutrition, Sarcopenia
- Trial name
- NCT05631379
- Testing
- Measurement of body composition with computed tomography (CT), GLIM malnutrition criteria, EWGSOP2 sarcopenia criteria
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- Institute of Oncology Ljubljana
Sarcopenic Obesity
Validation of an Algorithm for the Diagnosis of Sarcopenic Obesity
The proposed research project aims to investigate sarcopenic obesity (SO), a condition characterized by the combination of high body fat and low skeletal muscle mass, with a focus on muscle function.
- Trial name
- NCT06815978
- Testing
- DXA, ultrasonography, indirect calorimetry
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Elisa Giannetta
Obesity and Overweight
Sarcopenic Obesity: Estimation of Prevalence and Identification of Clinical and Biological Determinants in a Cohort of Adult Obese Patients and Longitudinal Follow-up
Context: Obesity, defined as excessive body fat, can lead to disability and loss of autonomy. If there is concomitant quantitative and qualitative muscle loss, sarcopenic obesity (SO) is suspected in this context.
- Trial name
- OBESAR-2 (NCT06880432)
- Testing
- Collection of fluid samples
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sarcopenic Obesity
Effects of the EatWelLog App on Diet Management for Older Adults With Sarcopenic Obesity
Sarcopenic obesity, characterised by concurrent reduced muscle mass and excess body fat, affects 11% of older adults worldwide, rising to 23% in those over 75.
- Trial name
- NCT06360432
- Testing
- Dietary modification program, Exercise training, The EatWellLog App
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Crohn's Disease, Malnutrition
Assessment of Nutritional Status of Patients With Crohn's Disease
Good nutritional status of patients with Crohn's disease (CD) is associated with better outcome of the disease and better health-related quality of life.
- Conditions
- Crohn's Disease, Malnutrition, Overweight and Obesity, Sarcopenia
- Trial name
- NCT03871634
- Where
- Greece
- Volunteers
- 250 people
- Sponsor
- Harokopio University
Obesity, Sarcopenic Obesity
Sarcopenic Obesity as a Risk of Premature Aging
Recently, numerous signaling proteins derived from adipose tissue and/or skeletal muscle have been described and are involved in the pathogenesis of obesity and the pathophysiology of aging.
- Conditions
- Obesity, Sarcopenic Obesity, Aging
- Trial name
- SARCOBEAGING (NCT05443711)
- Testing
- No intervention, observational study
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospital de Leon
Sarcopenia, Sarcopenic Obesity
Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults
Syndromes such as sarcopenia, sarcopenic obesity and osteosarcopenic obesity are commonly seen in older adults. They result from the impairment of muscle, bone and adipose tissue.
- Conditions
- Sarcopenia, Sarcopenic Obesity, Osteopenia, Osteoporosis
- Trial name
- NCT04122638
- Where
- Turkey (Türkiye)
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Goztepe Training and Research Hospital
Sarcopenic Obesity, Bariatric Surgery Candidate
Effect of Protein Supplementation and a Structured Exercise Program on Muscle in Women After Bariatric Surgery.
Obesity is considered a chronic disease that increases the risk of developing diseases that reduce life expectancy. The treatment of obesity is complex.
- Conditions
- Sarcopenic Obesity, Bariatric Surgery Candidate, Nutritional Deficiency, Protein Intolerance
- Trial name
- SarcoFit (NCT04771377)
- Testing
- Protein Supplementation
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Clinic of Barcelona
Sarcopenia, Obesity
Investigating the Link Between Advanced Glycation End Products (AGEs) and Muscle Wasting in Sarcobesity
The study aims to explore whether a high level of AGEs (Advanced Glycation end products) derived from the diet may mediate diet-related muscle loss in Western-type diet, influencing the onset and progression of sarcopenia…
- Trial name
- Westernage (NCT06438900)
- Where
- Italy
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Sarcopenia, Sarcopenic Obesity
Effects of a Multi-intervention Programme for the Elderly
1. To develop a multiactivity training programme. 2. To explore the effect of this programme on sarcopenia, sarcopenic obesity, cognitive impairment and Parkinson's disease. 3.
- Conditions
- Sarcopenia, Sarcopenic Obesity, Dementia
- Trial name
- NCT05720416
- Testing
- protein supplementation, muscle strength training, usual care
- Where
- Taiwan
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
Sarcopenia, Obesity
The Effectiveness of Lifestyle Intervention on Body Composition, Physical Performances and Quality of Life Among Elderly People in Long-term Care Facilities
Purpose: To understand the change in body composition, physical functions and quality of life of elderly residents with sarcopenic obesity in LTC facilities after the implementation of exercise intervention.
- Trial name
- NCT02912338
- Testing
- Resistant Training, Control Group
- Volunteers
- 123 people
- Sponsor
- Central Taiwan University of Science and Technology
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Peritoneal Dialysis Complication, Sarcopenic Obesity
The Effect Of Medical Nutritional Therapy On Patients With Sarcopenic Obesity Receiving Peritoneal Dialysis Treatment
In this study, it was aimed to evaluate the effectiveness of medical nutrition therapy to be applied to patients with sarcopenic obesity receiving peritoneal dialysis treatment by measuring anthropometric measurements and blood…
- Trial name
- NCT05797181
- Testing
- medical nutrition therapy in kidney diseases
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Atlas University
Obesity, Sarcopenia
Evaluation of Physical Performance in Old Adults With Sarcopenic Obesity
The primary objectives of the present study are to estimate the sarcopenic proportion in a cohort of obese older subjects who have been hospitalized.
- Trial name
- PREFISAR (NCT06299241)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Auxologico Italiano
Sarcopenia in Elderly, Sarcopenic Obesity
Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort
Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study Introduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle…
- Conditions
- Sarcopenia in Elderly, Sarcopenic Obesity, Frailty, Femoral Fractures
- Trial name
- NCT06705166
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Obesity, Sarcopenic Obesity
Efficacy of Protein Supplemented Very Low Calorie Meals on Weight Loss
This randomized clinical trial will evaluate the efficacy and safety of protein supplemented very low calorie meals on weight loss and weight loss maintenance among people with obesity.
- Trial name
- NCT04597788
- Testing
- Protein supplemented very low calorie diet program, Conventional low calorie diet program
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital