Clinical trials: Sarcopenia
Rheumatic Diseases
Treatment of Rheumatologic Patients With Sarcopenia
Sarcopenia is defined as a pathological condition related to muscle strength and muscle mass reduction. It is caused by ageing (primary sarcopenia) and diseases associated with systemic inflammation (secondary sarcopenia).
- Trial name
- REU-SA (NCT07135388)
- Testing
- Food for special medical purposes
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Bari
Activities of Daily Living, Functional Fitness
Vitality Acupunch Exercise Program for Sarcopenia Older Adults
This project was aimed to test the effects of a six-month VA program on the activities of daily living (ADL) and functional fitness of institutional older adults with sarcopenia.
- Trial name
- VA (NCT04504786)
- Testing
- Vitality acupunch (VA) exercise program, Control
- Where
- Taiwan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Age-Related Loss of Skeletal Muscle Mass, Aging
Agility Training for Older Adults to Improve Fall Risk Factors
In this randomized controlled trial the effect of 4 months of multi-component (strength, balance, cognition, endurance) exercise training intervention on measures of neuromuscular performance, cognition, and endurance as well as…
- Conditions
- Age-Related Loss of Skeletal Muscle Mass, Aging, Sarcopenia, Cognitive Decline
- Trial name
- AgilE (NCT05727254)
- Testing
- Agility training, Exercise recommendations, Exercise diary
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Oliver Faude
Urinary Bladder Neoplasm
The Importance of Muscle Function in Patients With Disseminated Bladder Cancer
This study investigates if reduced muscle mass and muscle function predispose to poor completion of oncological treatment in patients with bladder cancer (including cancer of the renal pelvis, ureter and urethra) and if muscle…
- Trial name
- NCT04144270
- Testing
- Evaluation of muscle mass and muscle function
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Splenic Abscess, Sarcopenia
Sarcopaenia is a Useful Risk Stratification Tool for Surgeons to Prognosticate Splenic Abscess Patients
Sarcopaenia is associated with poor prognoses of in-hospital mortality in splenic abscess patients. Investigators recommend its use by surgeons in the ED to rapidly risk stratify and identify patients requiring urgent and…
- Trial name
- NCT03967041
- Testing
- radiological defined sarcopenia
- Where
- Taiwan
- Volunteers
- 99 people
- Sponsor
- Chang Gung Memorial Hospital
Prader Labhart Willi Syndrome, Body Weight Changes
Prader-Willi Syndrome Body Composition
Adults aged over 18 years, with the diagnosis of Prader-willi syndrome will be recruited through the hospital's outpatient clinic for either as intervention group receiving therapeutic elastic band training, or as control group…
- Conditions
- Prader Labhart Willi Syndrome, Body Weight Changes, Sarcopenia
- Trial name
- NCT04597645
- Testing
- Therapeutic elastic band resistance training
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Sarcopenia, Chronic Lower Back Pain
Prevalence and Factors Associated With Sarcopenia in Pre-retirement Aged Adults With Chronic Non-specific Lower Back Pain
To study the prevalence of sarcopenia in a pre-retirement group with chronic lower back pain and factors associated between sarcopenia and chronic lower back pain in the pre-retirement group.
- Trial name
- NCT05894213
- Where
- Thailand
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Sarcopenia
Multidisciplinary Combined Exercise and Nutrition Intervention for Sarcopenia (2)
This is an empirical study, which aims to examine the effect of a 12-week combined exercise-nutrition intervention in older adults with sarcopenia and to provide data for clinical and policy decision-making of sarcopenia.
- Trial name
- MENTORS (NCT07028294)
- Testing
- Combined exercise and nutrition intervention
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Sarcopenia, Pseudoexfoliation Syndrome
Pseudoexfoliation Syndrome, Sarcopenia and Chronic Pain
Aim: Pseudoexfoliation syndrome (PEX) is a systemic disease of connective tissue, it can also contribute to sarcopenia and chronic musculoskeletal pain with common pathways. 1.
- Trial name
- NCT06121154
- Testing
- SARC-F questionnaire, Gait speed, The chair rise test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Sarcopenia
Diagnostic Evaluation of Sarcopenia in Elderly Patients
Sarcopenia is a generalized progressive skeletal muscle disorder that represents a related physiological vulnerability that is associated with or increases the likelihood of adverse outcomes, including falls, fractures, physical…
- Trial name
- NCT04451005
- Testing
- 0
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stroke, Acute
Sarcopenia in the Acute Stroke
Regardless of the cause of immobilization, within days or weeks there is rapidly a decrease in strength and muscle mass, which can lead to sarcopenia.
- Trial name
- SARCOSTROKE (NCT06603701)
- Testing
- Bioimpedancemetry, Dynamometry
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Non-sarcopenic Subjects, Possible Sarcopenia
Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia
The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure…
- Conditions
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- Trial name
- EMTC-Sarc (NCT07658599)
- Testing
- oral muscle strength training
- Where
- Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Hepatic Encephalopathy
Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy
This is a global study to compare the effects of AXA1665, an orally active mixture of amino acids, compared to placebo, on cognitive and physical function, as well as the safety and tolerability of AXA1665.
- Trial name
- EMMPOWER (NCT04816916)
- Testing
- AXA1665
- Where
- 40 sites in United States, Canada and 5 more
- Volunteers
- 12 people
- Sponsor
- Axcella Health, Inc
Sarcopenia, Diagnosis
Evaluating SARC-F, SARC-CalF, and Calf Circumference as Diagnostic Tools for Sarcopenia in Thai Older Adults: Results From a Nationwide Study
As the elderly population grows, musculoskeletal disorders, including sarcopenia, have become a critical area of study due to their association with falls and fractures.
- Trial name
- NCT06558617
- Testing
- SARC-F Questionnaire, Calf Circumference Measurement, SARC-CalF Questionnaire
- Where
- Thailand
- Volunteers
- 2,543 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Cardiac Ageing, Physical Activity
The Cardio-Sarcopenia Study
The use of surrogate markers such as body mass index (BMI) as a target outcome of physical activity may not be appropriate in older adults who are at risk of muscle sarcopenia.
- Conditions
- Cardiac Ageing, Physical Activity, Older Adults, Sarcopenia
- Trial name
- NCT05203406
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Inflammatory Bowel Diseases
Screening of Nutritional Status and Sarcopenia Among Patients With IBD
1. Screening of malnutrition in patients with IBD and its relation to severity of the disease. 2. Determination of severity of malnutrition in IBD patients. 3. Assessment of Sarcopenia in patients with IBD.
- Trial name
- NCT05877209
- Volunteers
- 100 people
- Sponsor
- Assiut University
Inactivity, Physical, Treatment Adherence and Compliance
VR vs. Conventional Cycling Exercise for Geriatric Inpatient Physical Activation
The aim of this study is to investigate whether virtual reality assisted stationary cycling exercise results in more physical activity than conventional unsupervised stationary cycling exercise.
- Conditions
- Inactivity, Physical, Treatment Adherence and Compliance, Hospital Acquired Condition, Sarcopenia
- Trial name
- NCT05123638
- Testing
- Virtual reality cycling exercise, Unsupervised stationary cycling exercise
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Breast Neoplasms, Body Composition
Longitudinal Body Composition Assessment in Breast Cancer Patients
This observational cohort study aims to track longitudinal changes in body composition, including skeletal muscle mass and fat distribution, in patients diagnosed with breast cancer.
- Conditions
- Breast Neoplasms, Body Composition, Sarcopenia, Fat Redistribution
- Trial name
- NCT07472803
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Aging, Undernutrition
Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products
This study aims to assess the digestibility and efficacy of the study groups previously developed innovative plant-based protein and fibre products.
- Conditions
- Aging, Undernutrition, Appetite Loss, Age-Related Sarcopenia
- Trial name
- NCT05420142
- Testing
- Net peripheral AA appearance following ingestion of 3 selected PPF products compared to whey
- Where
- 2 sites in Ireland, Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Sarcopenia, Malnutrition
Impact of Preoperative Sarcopenia on Morbidity and Mortality in Patients Operated on From Digestive Cancers
Sarcopenia (loss of muscle mass and function) can be observed at any age and results of multiple factors (age, activity, inflammatory factors, nutritional status...).
- Conditions
- Sarcopenia, Malnutrition, Pancreatic Cancer, Liver Cancer
- Trial name
- A15-10 (NCT02811666)
- Testing
- Assessment of sarcopenia by CT-Scan, hand gauge
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims