Non-sarcopenic SubjectsEMTC-SarcNCT07658599
Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia
A study testing oral muscle strength training in people with Non-sarcopenic Subjects and Possible Sarcopenia, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
Trial summary
The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure in middle-aged and elderly sarcopenia subjects when given edible chewing training colloidal… Read more about this study
- Who is it for?
- Ages 45 years and olderHealthy volunteers can take part
- Conditions the study is for
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- What is being tested?
- oral muscle strength training
- Type of treatment
- Pill or oral medicine, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 68 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Mar 2024to 25 Apr 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 45 years old (inclusive) or older
- The general public or the institution has stayed for more than 3 months (inclusive)
- Those who accept the experimental design and intervention, and are willing to sign the consent form
- The source of the diet is that you can eat by mouth independently
- Those who meet the diagnosis definition of sarcopenia by the Asian Sarcopenia Consensus Association
- No history of chewing and swallowing
Who cannot join
- Those who may have allergic or uncomfortable reactions to edible chewing colloids (honey flavor)
- Feeders
- Other dietitians who cannot complete this researcher
- Those who cause discomfort when chewing (such as temporomandibular joint pain, oral ulcers, severe tooth decay, etc.)
- Those who report choking and coughing when chewing
Trial locations and contacts
1 site in 1 country.
About this study
The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure in middle-aged and elderly sarcopenia subjects when given edible chewing training colloidal intervention.This trial method will recruit 120 subjects for oral strength training twice a day for 8 weeks, and compare the difference in chewing level between the subjects using the oral strength training intervention and the oral strength training intervention before and after the test. The differences between dental occlusal force and tongue pressure after training were also explored. The experiment mainly evaluated the scales related to dental occlusal force, tongue pressure, and quality of life, because the quality of oral muscles is highly correlated with the diet and lifestyle of the elderly, and also affects the physical health and mobility of the elderly. Although the loss of muscle mass due to aging may be unavoidable, appropriate oral strength training intervention may delay or modify the adverse effects of sarcopenia and improve quality of life in sarcopenia subjects.
- Being tested
- oral muscle strength training
- Keywords
- sarcopenia, chewing, oral strength training, muscle strength
- Medical subject headings
- Sarcopenia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
oral muscle strength trainingBehavioural
Also called NON
Oral muscle strength tests are conducted the day before the intervention and during the eighth week after the intervention.
| Study group | Role | What they receive |
|---|---|---|
| NON | Other | NON Receives: Behavioral: oral muscle strength training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.
- The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women
- 6-meter walking speed less than 1.0 second/meter
- 5-time chair stand test greater than or equal to 12 seconds
- Short physical performance battery, SPPB greater than or equal to 9 points
Measured: From Intervention to Experiment Completion (eight weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jun 2026
- Study start1 Mar 2024
- Primary completion25 Apr 2024
- Study completion25 Apr 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Non-sarcopenic SubjectsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 68 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chang Gung University of Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07658599
- Sponsor's protocol ID
- 202301544A3C601
- Other IDs
- ZRRPF3N0061
- Acronym
- EMTC-Sarc
- Status last verified
- Jun 2026
- First submitted
- 10 Jun 2026
- Last updated
- 22 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia
- ClinicalTrials.gov ID
- NCT07658599
- Acronym / sponsor ID
- EMTC-Sarc / 202301544A3C601
- Keywords
- sarcopenia, chewing, oral strength training, muscle strength
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 68 participants (actual)
- Lead sponsor
- Chang Gung University of Science and TechnologyUniversity, hospital or other
- Study start
- 1 Mar 2024 (actual)
- Primary completion
- 25 Apr 2024 (actual)
- Study completion
- 25 Apr 2024 (actual)
- First posted
- 22 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure in middle-aged and elderly sarcopenia subjects when given edible chewing training colloidal intervention.This trial method will recruit 120 subjects for oral strength training twice a day for 8 weeks, and compare the difference in chewing level between the subjects using the oral strength training intervention and the oral strength training intervention before and after the test. The differences between dental occlusal force and tongue pressure after training were also explored. The experiment mainly evaluated the scales related to dental occlusal force, tongue pressure, and quality of life, because the quality of oral muscles is highly correlated with the diet and lifestyle of the elderly, and also affects the physical health and mobility of the elderly. Although the loss of muscle mass due to aging may be unavoidable, appropriate oral strength training intervention may delay or modify the adverse effects of sarcopenia and improve quality of life in sarcopenia subjects.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| NON | Other | Behavioral: oral muscle strength trainingNON |
Who may qualify
- Ages
- 45 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- 45 years old (inclusive) or older
- The general public or the institution has stayed for more than 3 months (inclusive)
- Those who accept the experimental design and intervention, and are willing to sign the consent form
- The source of the diet is that you can eat by mouth independently
- Those who meet the diagnosis definition of sarcopenia by the Asian Sarcopenia Consensus Association
Key exclusion criteria (5 listed)
- Those who may have allergic or uncomfortable reactions to edible chewing colloids (honey flavor)
- Feeders
- Other dietitians who cannot complete this researcher
- Those who cause discomfort when chewing (such as temporomandibular joint pain, oral ulcers, severe tooth decay, etc.)
- Those who report choking and coughing when chewing
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| oral muscle strength trainingAlso: NONOral muscle strength tests are conducted the day before the intervention and during the eighth week after the intervention. | Behavioural | NON |
Primary outcome
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.
Time frame: From Intervention to Experiment Completion (eight weeks)
* The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jun 2026.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing oral muscle strength training in people with Non-sarcopenic Subjects and Possible Sarcopenia, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established. (time frame: From Intervention to Experiment Completion (eight weeks)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jun 2026.