Clinical trials: Sarcopenia
Sarcopenia, Chronic Kidney Diseases
Sarcopenia, Fall and Osteoporosis in Chronic Kidney Disease
This study is a cross-sectional study that wishes to investigate whether there is an increased incidence of sarcopenia in patients with chronic kidney disease compared to the Danish background population.
- Conditions
- Sarcopenia, Chronic Kidney Diseases, Osteoporosis
- Trial name
- NCT04515342
- Testing
- DXA, Muscle strength and function assessment, Blood samples
- Where
- 2 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Herlev Hospital
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Neoplasm Malignant Female
Supervised Exercise During Neoadjuvant Chemotherapy for Breast Cancer
The goal of this clinical trial is to learn whether supervised exercise is practical and safe for women receiving chemotherapy before surgery for breast cancer.
- Trial name
- NCT07764341
- Testing
- Supervised exercise
- Where
- Bahrain
- Volunteers
- 80 people
- Sponsor
- King Hamad University Hospital, Bahrain
Sarcopenia, Muscle Loss
Biomarkers of Sarcopenia and Frailty in Geriatric Patients
During the last decades there has been an increase in the relative proportion and life expectancy of elderly people. Hence, the number of elderly with diseases and disabilities related to aging will increase and consequently…
- Conditions
- Sarcopenia, Muscle Loss, Fall Patients
- Trial name
- BioFrail (NCT05795556)
- Testing
- Assessing sarcopenia and potential biomarkers of sarcopenia in fall patients
- Where
- Denmark
- Volunteers
- 508 people
- Sponsor
- Herlev and Gentofte Hospital
Sarcopenia, Physical Exercise
Efficacy of the Consumption of a Spinach Extract on Muscle Function in Subjects Over 50 Years of Age
Controlled, randomized, single-center, double-blind clinical trial, with two parallel branches depending on the product consumed, to measure the efficacy of a supplement extracted from spinach on muscle strength in subjects over…
- Trial name
- SPISAR (NCT04612127)
- Testing
- Dietary supplement consumption and physical exercise
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Sarcopenia, Peripheral Arterial Disease
Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia
To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.
- Conditions
- Sarcopenia, Peripheral Arterial Disease, Chronic Limb Threatening Ischemia
- Trial name
- SAC (NCT07037979)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Fudan University
Sarcopenia
Nutritional Supplementation in the Elderly With Weight Loss
Many elderly experience weight loss and weakness with normal aging. Although there is extensive literature regarding nutritional advice for the elderly, there are few well- designed studies evaluating the effect of oral nutrition…
- Trial name
- Elderly (NCT04350762)
- Testing
- Protein shake + Fish Oil
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Osteoporosis, Postmenopausal
Vascular Function, Sarcopenia and Pain in Postmenopausal Osteoporosis
This study aims to follow a cohort of osteoporotic patients treated with anti-osteoporotic drugs and to evaluate the impact of these treatments on the osteoporosis-cardiovascular-sarcopenia triad and on pain.
- Trial name
- VASCO (NCT05228262)
- Testing
- Cohort follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gastrointestinal Stromal Tumours
Sarcopenia in Patients With Gastrointestinal Stromal Tumours
The treatment of advanced gastrointestinal stromal tumours (GIST) has shifted since the arrival of targeted therapies. Imatinib is an active multikinase inhibitor that mainly targets C-kit tyrosine-kinase receptors and the…
- Trial name
- SARCO-GIST (NCT02877368)
- Testing
- Computed tomography
- Where
- France
- Volunteers
- 31 people
- Sponsor
- CHU de Reims
Breast Cancer Survivorship, Sarcopenia
Nutrition, Exercise, and Breast Cancer Survivorship
The purpose of the study is to examine the effects of resistance training on the reasons (mechanisms) underlying the development of fatigue, muscle weakness and wasting (sarcopenia), and impaired physical functioning (poor…
- Trial name
- NCT01151488
- Testing
- Resistance Training
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Sarcopenia
Ankle Assistance and Resistance in Older Adults
The goal of this research protocol is to improve mobility in older individuals through advances in wearable assistive devices by focusing on two specific aims.
- Trial name
- NCT06284525
- Testing
- Ankle resistance and biofeedback
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Older Adults Without Any Specific Clinical Condition
Essential Amino Acid Supplementation Enhances Post-prandial Amino Acid Availability Following a Standard-protein Breakfast in Older Adults
Healthy older adults and those who have acute and chronic conditions suffer from reduced protein intake and are at risk of developing both chronic and acute sarcopenia.
- Trial name
- NCT07754760
- Testing
- Essential amino acid supplement
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Sarcopenia, Chronic Lung Disease
Feasibility of Proteomics in Chronic Lung Disease With Sarcopenia
Sarcopenia, the loss of muscle mass and strength with ageing, is a prevalent condition in older adults, particularly those with chronic lung diseases like COPD and interstitial lung disease.
- Trial name
- NCT06312774
- Testing
- This is observational study
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College, London
Sarcopenia
Fish Protein Supplementation and Sarcopenia Outcomes in Carehomes
The proposed study aims to investigate the effect of consuming 12.5g (twice daily) Blue Whiting Protein Hydrolysates (BWPH) daily for 6 weeks on whole body lean mass tissue and measures of muscle strength and functionality in…
- Trial name
- SARCO_CARE (NCT05637450)
- Testing
- Blue Whiting Protein Hydrolysate
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Colorectal Cancer Survivors
Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia
PURPOSE: To investigate the effects of low-load resistance training combined with blood flow restriction on muscle strength, functional performance, and cancer-related fatigue in colorectal cancer survivors with probable…
- Trial name
- NCT07874035
- Testing
- Low load blood flow restriction resistance training, Low load resistance training without Blood Flow Restriction
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Ahmed Adel Ahmed Elsayed Ali Radwan
Frailty, Sarcopenia
Selenium, Sarcopenia, and Frailty in Hemodialysis
Chronic kidney disease (CKD) is a significant public health issue with an increasing prevalence worldwide. In patients undergoing hemodialysis (HD) in particular, various factors-such as chronic inflammation, oxidative stress…
- Conditions
- Frailty, Sarcopenia, Selenium
- Trial name
- NCT07896876
- Testing
- FRAIL scale, sarc-f, time up go test
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Cirrhosis of the Liver, Ascites
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
The goal of this observational study is to learn how liver cirrhosis affects the diaphragm, the main muscle used for breathing, in adults.
- Conditions
- Cirrhosis of the Liver, Ascites, Pleural Effusion Disorder, Hepatocellular Carcinoma (HCC)
- Trial name
- NCT07667608
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cognitive Impairment, Insulin-like Growth Factor 1
IGF-1, Sarcopenia and Mortality: a Cohort Study in Patient With Cognitive Impairment
Insulin-like growth factor 1 (IGF)-1 is an important neuromyotrophic hormone. Disregulation of this hormone has been reported to influence the genesis of cognitive impairment and dementia in the elderly patients.
- Trial name
- ISAAC (NCT02139410)
- Testing
- IGF-1 serum value
- Where
- 2 sites in Italy
- Volunteers
- 589 people
- Sponsor
- University of Roma La Sapienza
Sarcopenia
L1 M1 of LDCT for Low Muscle Mass Measurement
The first lumbar spine muscle index (L1 MI) on computed tomography (CT) obtained by measuring muscle surface at the first lumbar vertebrae (L1) level is an indicator of total skeletal mass in specific populations.
- Trial name
- NCT04547478
- Testing
- low dose chest CT(LDCT)
- Where
- Taiwan
- Volunteers
- 3,304 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Gastro-Esophageal Cancer
Cancer-associated Cachexia in Patients With Incurable Gastroesophageal Cancer
Patients with incurable gastroesophageal cancer are at high risk of cancer cachexia with an estimated prevalence of 60-80%. Cancer cachexia is defined as ongoing loss of skeletal muscle mass with or without loss of fat mass and…
- Trial name
- NCT06137508
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet