Clinical trials: Salt; Excess
Hypertension, Salt; Excess
Impact of Self-monitoring of Salt Intake by Salt Meter in Hypertensive Patients
Hypertension is one of the most common chronic medical conditions. The concerned sequelae are the cardiovascular complications, especially acute myocardial infarction and stroke.
- Trial name
- SMAL-SALT (NCT04286802)
- Testing
- Salt-meter, Education
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Sodium Excess, Hypertension
Effects of a Six-Day Whole-Diet Intervention on Taste Perception and Dietary Behaviour in Young Adults
This study aims to investigate the effects of a specific diet modification on the pleasantness, desire, and saltiness intensities of selected foods and an ad libitum breakfast buffet through a randomized controlled trial with…
- Conditions
- Sodium Excess, Hypertension, Salty Taste
- Trial name
- NCT07726394
- Testing
- Experimental: Increased Salty Food Intake, Experimental: Decrease Salty Food Intake, Active Comparator: Maintain Usual Diet
- Where
- Malaysia
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Sunway University
Hypertension, Salt; Excess
Intervention for Monitoring of Salt Intake in Hypertensive Patients
Sodium is an essential nutrient for humans, but excessive sodium consumption is causally associated with high blood pressure and increase risk of cardiovascular diseases.
- Trial name
- NCT05397054
- Testing
- Education, Reformulation, Environmental change
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Mahidol University
Dialysis, Excess Interdialytic Weight Gain
Haemodialysis fMRI Salt Appetite Study
1. Assessing how the rapid removal of salt and water by haemodialysis alters regional brain activity (by measurement of the brain blood oxygen level-dependent (BOLD) signal using functional MRI) during tasting of soup of…
- Trial name
- HeMSA (NCT04011254)
- Testing
- haemodialysis
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Sodium Excess
Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics
High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who…
- Trial name
- NCT04233957
- Testing
- High Sodium
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Metabolic Ketoacidosis, Ketoacidemia
0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis
Severe diabetic ketoacidosis (DKA) is a potentially serious complication of diabetes mellitus. The treatment regimen is based on insulin and rehydration. The choice of rehydration solution is a question that remains open.
- Conditions
- Metabolic Ketoacidosis, Ketoacidemia, Acetonemia, Acetonuria
- Trial name
- NCT05808972
- Testing
- Sodium chloride 0.9% (SC), Ringer lactate (RL)
- Where
- Tunisia
- Volunteers
- 92 people
- Sponsor
- Tunis University
Salt; Excess, Pregnancy Related
Dietary Salt During Pregnancy and Maternal Vascular Function
The main goal of this study is to investigate the association of dietary salt intake during pregnancy with systemic micro- and macrovascular reactivity and uteroplacental vascular function of the mother, and to examine the…
- Trial name
- NCT05048225
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
High Blood Pressure, Salt; Excess
Salt-Sensitivity and Immunity Cell Activation
Salt-sensitive hypertension affects nearly 50% of the hypertensive and 25% of the normotensive population, and strong evidence indicates that reducing salt intake decreases blood pressure and cardiovascular events.
- Conditions
- High Blood Pressure, Salt; Excess, Inflammation
- Trial name
- NCT03753204
- Testing
- Furosemide 40 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Obesity, Hypertension
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans
Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms…
- Conditions
- Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
- Trial name
- NCT04021355
- Testing
- Oral sodium supplementation
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hyperaldosteronism; Primary, Hypertension
Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment.
This study looks at how hypertensive patients, with high levels of aldosterone (hyperaldosteronism) differ from hypertensive patients without hyperaldosteronism with regards to markers of salt appetite.
- Conditions
- Hyperaldosteronism; Primary, Hypertension, Salt; Excess, Appetite Disorders
- Trial name
- AldoSalt (NCT04556279)
- Testing
- adrenalectomy, Aldosterone Antagonist
- Where
- United Kingdom
- Sponsor
- Imperial College London
Salt; Excess, Hypertension
Ketone Ester And Salt (KEAS) in Older Adults
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans.
- Conditions
- Salt; Excess, Hypertension, Aging, Inflammation
- Trial name
- KEAS-O (NCT06868719)
- Testing
- No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hypertension,Essential, Salt; Excess
Genetic of Response to Acute Saline Load Test in Hypertension (Naload)
NHP referred to our outpatient clinic will be enrolled (150 newly recruited) in acute saline test for phenotype characterisation of PNat relationship(7).
- Conditions
- Hypertension,Essential, Salt; Excess, Genetic Hypertension, Genetic Predisposition to Disease
- Trial name
- Naload (NCT04625569)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Ospedale San Raffaele
Salt; Excess, Blood Pressure Disorders
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.
- Trial name
- PEPC3 (NCT04026776)
- Testing
- Allopurinol, Dietary Intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hypertension, Sodium Excess
Effects of Salt on Serum Osmolarity and Hemodynamics Parameters
Diets containing excessive salt (>12 g/day) have negative effects on kidney and cardiovascular system. Considering this known fact, the investigators aimed to study if the amount of the water taken with excessive salt had any…
- Conditions
- Hypertension, Sodium Excess, Oxidative Stress, Inflammation
- Trial name
- NCT03314727
- Testing
- High salt (NaCl) intake
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koç University
Salt; Excess
Dietary Salt and Microvascular Function
It is well accepted that high-salt (HS) intake is an essential risk factor in development and progression of hypertension. Results of some recent studies suggest that some of the deleterious effects of a HS diet are independent…
- Trial name
- NCT02727426
- Testing
- Low Salt (LS) diet, High Salt (HS) diet
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Salt; Excess, Hypertension
Study With an Innovative Equipment to Monitor and Control SALT During Cooking
In this study, the researchers will evaluate the efficacy of an intervention using the SALT CONTROL H instrument (an innovative equipment to monitor and control salt) in workers at the University of Porto to reduce dietary salt…
- Trial name
- iMC_SALT (NCT03974477)
- Testing
- SALT CONTROL H equipment to control and monitor salt during cooking process
- Where
- Portugal
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Salt Hypertension From Excess Dietary Salt, Lens Opacities
Salt Sensitivity Hypertension and Lens Opacities
Salt-sensitive hypertension (SSH) accounts for about the half of all Hypertension (HT) cases .In SSH, Na+/K+-ATPase activity is impaired.
- Trial name
- NCT03385070
- Testing
- Lens examination
- Where
- Turkey (Türkiye)
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Salt; Excess, Hypertension
Ketone Ester and Salt (KEAS) in Young Adults
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans.
- Trial name
- KEAS (NCT05545501)
- Testing
- No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obesity, Cardiovascular Risk Factor
Visualizing Vascular Mechanisms of Salt Sensitivity
This study aims to assess the salt sensitive blood pressure response to dietary salt load compared with radiological markers of salt handling.
- Conditions
- Obesity, Cardiovascular Risk Factor, Salt; Excess
- Trial name
- NCT03696433
- Testing
- Low-salt diet, High-salt diet
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Blood Pressure, Salt; Excess
Sodium Glucose Cotransporter-2 Inhibitors and Salt-sensitivity in Type 2 Diabetes
The goal of this interventional study is to test whether sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce the effects of high dietary sodium intake in patients with type 2 diabetes.
- Conditions
- Blood Pressure, Salt; Excess, Diabete Type 2
- Trial name
- SALT (NCT06007157)
- Testing
- Hypersodic/Hyposodic diet
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana