Clinical trials: Safety Study
Early Onset Sepsis, Preterm Neonates
Optimizing PreTerm Infant Ampicillin Dosing
The goal of this clinical trial is to learn if preterm infants who are prescribed antibiotics shortly after birth can safely receive a shorter course of antibiotics (24 to 36 hours instead of 48 hours).
- Conditions
- Early Onset Sepsis, Preterm Neonates, NICU, Ampicillin
- Trial name
- OPTI-Amp (NCT07610486)
- Testing
- Ampicillin prescribed by provider per standard of care for evaluation of early onset sepsis
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
CAR-T Long Term Follow Up (LTFU) Study
Per Health Authorities guidelines for gene therapy medicinal products that utilize integrating vectors (e.g. lentiviral vectors), long term safety and efficacy follow up of treated patients is required.
- Trial name
- PAVO (NCT02445222)
- Testing
- Previously treated CAR-T patients
- Where
- 120 sites in United States, Australia and 21 more
- Volunteers
- 1,105 people
- Sponsor
- Novartis Pharmaceuticals
Safety, Efficacy
Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy
This study aims to evaluate and compare the safety, efficacy, and clinical outcomes of papillary and non-papillary renal access during percutaneous nephrolithotomy (PCNL), and to determine whether non-papillary puncture can be…
- Conditions
- Safety, Efficacy, Papillary, NonPapillary
- Trial name
- NCT07855354
- Testing
- Papillary access puncture, Non-papillary access puncture
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Patient Safety, Patient Safety Education
Patient Safety Competency-Building Program for Healthcare Professionals in Pediatric Cardiac Critical Care in Ethiopia
This study aims to develop and evaluate a patient safety competency-building program for healthcare professionals involved in pediatric cardiac critical care in Ethiopia.
- Trial name
- NCT07844369
- Testing
- Patient Safety Competency-Building Program
- Where
- Ethiopia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Woong-Han Kim
Patient Safety
Evaluating a Fingerprint System to Improve Patient Identification in Cardiac Surgery
The purpose of this prospective observational pilot study is to evaluate the usability, workflow integration, and operational feasibility of a fingerprint-based patient identification system (the Heuristik system) within…
- Trial name
- NCT07846644
- Testing
- Heuristik Fingerprint Identification System
- Volunteers
- 65 people
- Sponsor
- Heuristik Technologies SL
Patient Safety, Peripheral Intravenous Catheter-Related İnfiltration
Standardized Patient and In Situ Simulation for IV Infiltration Recognition
Peripheral intravenous catheters (PIVCs) are widely used invasive devices in hospital settings and are associated with a broad range of complications, among which infiltration is one of the most common and clinically significant.
- Trial name
- NCT07514247
- Testing
- Intervention: Standardized Patient Simulation, Intervention: In Situ Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selçuk Görücü
To Evaluate the Efficacy and Safety of Selected TCM Elbow Manipulation in Treating, Lateral Epicondylitis
Efficacy and Safety of Selected Traditional Chinese Medicine Elbow Manipulation Versus Mill's Manipulation as Control for Lateral Epicondylitis
Background: Lateral epicondylitis (LE), also referred to as lateral elbow tendinopathy and tennis elbow, is commonly seen clinically as an orthopedic disease.
- Trial name
- NCT07843771
- Testing
- Selected Traditional Chinese Medicine manipulation, Mill's Manipulation
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Health Care Providers, Patient Safety
Acceptance and Perceived Benefits of Digitalization by Medical Assistants
The aim of this project is to improve the integration of digital processes, including e-prescriptions, within medical and dental practices for healthcare professionals.
- Conditions
- Health Care Providers, Patient Safety, eHealth
- Trial name
- ANDI-MFA (NCT06269250)
- Testing
- Policy Change
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Jacobs University Bremen gGmbH
Feasibility and Safety of a Low-field MRI, Acute Brain Injury
Low-Field Bedside Brain Magnetic Resonance Imaging in Pediatric Extracorporeal Membrane Oxygenation
The primary object of the study is to further characterize safety and feasibility of low-field bedside MRI in pediatric and neonatal ECMO patients.
- Conditions
- Feasibility and Safety of a Low-field MRI, Acute Brain Injury, Extracorporeal Membrane Oxygenation Complication
- Trial name
- NCT06074406
- Testing
- Hyperfine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Mercy Hospital Kansas City
Sleep, Fatigue
Sleep, Mindfulness, and Shift-Level Safety Performance in Perianesthesia Nurses
Perianesthesia (preoperative and postanesthesia care unit, PACU) nurses work rotating, often extended shifts that can disrupt sleep and increase fatigue, both of which are recognized threats to patient safety in high-acuity…
- Conditions
- Sleep, Fatigue, Patient Safety
- Trial name
- NCT07832721
- Testing
- Sleep, Mindfulness, and Shift-Level Safety Observation Toolkit
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Missed Nursing Care, Patient Safety
Perioperative Nursing Workload, Missed Care, and Near-Miss Events
This prospective, single-center observational study examines the relationship between perioperative nursing workload and safety-critical perioperative nursing care in the operating rooms of Agri Training and Research Hospital.
- Conditions
- Missed Nursing Care, Patient Safety, Workload
- Trial name
- NCT07834580
- Testing
- Structured Direct Observation and Workload Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Pediatric Safety
Pediatric Acceptability Evaluation of a Cosmetic Product
The goal of this clinical trial is to evaluate the dermatological safety and acceptability of a cosmetic product in healthy pediatric participants.
- Trial name
- NCT07839104
- Testing
- moisturizing cream
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Safety Study
Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting.
The Abreu BTT 700 Temperature Management System (TMS) is a device that gently raises the body temperature of the participant to a fever-range level in a controlled setting. There will be one study treatment session.
- Trial name
- BTT (NCT07564440)
- Testing
- Hyperthermia
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marc Abreu
Randomised Clinical Trial, Double Blind
Phase I Study of VLPDEN-02 Dengue Vaccine in Healthy Adults
This is a Phase 1, randomized, double-blind, placebo-controlled, dose escalation study. Forty-two flavivirus-naïve adults will be enrolled and will receive 3 administrations of VLPDEN-02 or control at days 0, 28, and 56.
- Conditions
- Randomised Clinical Trial, Double Blind, Dengue, Challenge Test
- Trial name
- NCT07831473
- Testing
- VLPDEN-02 1.0 µg (0.25 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 10 µg (2.5 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 100 µg (25 µg of each VLP) + ALFQ adjuvant
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- VLP Therapeutics
Safety
Evaluation of Allergenicity by HRIPT and Phototest
This clinical study will evaluate the dermatological safety and allergenic potential of a cosmetic product. The study will use the Human Repeat Insult Patch Test (HRIPT) and phototest procedures to assess whether the product may…
- Trial name
- HRIPT + FOTO (NCT07797192)
- Testing
- Blancy Pro
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Safety and Tolerability in Healthy Volunteers
Safety and Tolerability Evaluation of BP-LT
This study evaluates the safety and tolerability of the food ingredient BP-LT when added to a daily diet. BP-LT is a stable protein ingredient being functional in the gastrointestinal tract and without systemic absorption.
- Trial name
- NCT07819695
- Testing
- BP-LT
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Patient Safety Education and Nursing Students' Attitudes Toward Medical Errors
Effects of Two Teaching Methods on Nursing Students' Attitudes Toward Medical Errors
The aim of this study is to compare the effects of patient safety education delivered through the Pecha Kucha method, scenario-based teaching, and traditional teaching on nursing students' attitudes toward medical errors.
- Trial name
- NCT07822438
- Testing
- Pecha Kucha-Based Patient Safety Education, Scenario-Based Patient Safety Education, Traditional Lecture-Based Patient Safety Education
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Patient Safety, Medical Errors
Specialist Review of Harm Ratings for Clinical Responses Acronym: NOHARM
The purpose of this study is to determine how closely potential-harm ratings assigned using the NOHARM rubric agree with independent ratings from specialty-matched physicians.
- Trial name
- NCT07823062
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stanford University
Safety and Tolerability in Healthy Volunteers
Safety and User Experience of BP-CBB
This study is the first-in human study for the food ingredient BP-CBB and aims aims to build on the excellent safety and tolerability observed in the extensive food safety assessment performed for BP-CBB, as well as the consumer…
- Trial name
- NCT07628608
- Testing
- BP-CBB
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Evaluate Web-based Child Safety Intervention Website for Parents
Evaluation of an Online Educational Child Injury Prevention Intervention
The goal of this evaluation is to learn what effect the Safe Kids Washington website, a self-guided web-based intervention program, has on: Parent knowledge of injury prevention strategies Parent attitudes, self-efficacy and…
- Trial name
- NCT07804355
- Testing
- Safe Kids Washington, Active Control condition
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Oregon